# hmmscan :: search sequence(s) against a profile database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query sequence file: AA/23726_FusoPortal_Gene_360.faa # target HMM database: Pfam-A.hmm # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: 23726_FusoPortal_Gene_360 [L=188] Description: # 395310 # 395873 # -1 # ID=1_360;partial=00;start_type=ATG;rbs_motif=None;rbs_spacer=None;gc_cont=0.234 Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-21 75.1 1.6 3.1e-21 75.1 1.6 1.6 2 PDDEXK_9 PD-(D/E)XK nuclease superfamily 7.4e-06 25.5 5.2 1.1e-05 24.9 5.1 1.5 1 AAA-ATPase_like Predicted AAA-ATPase ------ inclusion threshold ------ 0.039 13.6 0.6 0.065 12.8 0.6 1.3 1 DUF1673 Protein of unknown function (DUF1673) 0.14 11.5 0.2 0.23 10.8 0.1 1.3 1 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domai 0.31 11.2 6.6 0.2 11.8 1.7 2.5 2 PYRIN PAAD/DAPIN/Pyrin domain Domain annotation for each model (and alignments): >> PDDEXK_9 PD-(D/E)XK nuclease superfamily # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.1 0.0 1 3.4e+03 79 79 .. 61 61 .. 26 84 .. 0.62 2 ! 75.1 1.6 9.4e-25 3.1e-21 2 98 .. 90 187 .. 89 187 .. 0.97 Alignments for each domain: == domain 1 score: -2.1 bits; conditional E-value: 1 PDDEXK_9 79 e 79 + 23726_FusoPortal_Gene_360 61 K 61 2 PP == domain 2 score: 75.1 bits; conditional E-value: 9.4e-25 PDDEXK_9 2 nEkyyksvfyalla.lslgyevksEdetnkGriDlllkpkektkkkiyifEfKylkekesekekaeealeQikekgyaekyked 84 nE++y+ +++++ l+ y++ks+ +++ Gr+D+l++ ++++k ++i+EfK++++ e+ +e ++eal+Qi++k+y+ ++k++ 23726_FusoPortal_Gene_360 90 NEAFYHDLIMGMGLyLEGEYITKSNIKSGLGRYDFLIE-PKNKSKRAFIMEFKSTDSVEKLEEISKEALKQIEDKKYDISLKQN 172 8***********999***********************.77788**************************************** PP PDDEXK_9 85 g.kkikkigivfdgk 98 g k+i++igi+f gk 23726_FusoPortal_Gene_360 173 GiKEITHIGIAFYGK 187 ************986 PP >> AAA-ATPase_like Predicted AAA-ATPase # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 5.1 3.3e-09 1.1e-05 96 176 .. 17 97 .. 4 173 .. 0.81 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 3.3e-09 AAA-ATPase_like 96 eeleeslke.klkelekefgkkkeekslakrlkelieraaektgkkvvvLiDEYDkpilealeeeelaeelreflrefykvl 176 + l ++l+e ++ +k ++++ + ++l+++lk l + ++ek++kkvvvLiDEY++ + e+l ++ +++++++ +fy+ l 23726_FusoPortal_Gene_360 17 QYLLKELNEnDYSKFKKVLSEEANLSNLGTTLKFLTKILYEKYNKKVVVLIDEYEENLQEILLTS-VNNDTKKGNEAFYHDL 97 4444444441455666666777779999******************************9999988.8889998888888765 PP >> DUF1673 Protein of unknown function (DUF1673) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.6 1.9e-05 0.065 165 223 .. 9 73 .. 4 80 .. 0.72 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 1.9e-05 DUF1673 165 llillsyvesiagelqlge.....vvssfisgllllllwliylqviywekkNkkti.vrkrygkk 223 l+ + s+++ el ++ v+s + l l ++l +l+ i +ek+Nkk++ + ++y+++ 23726_FusoPortal_Gene_360 9 LSDFFSEYQYLLKELNENDyskfkKVLSEEANLSNLGTTLKFLTKILYEKYNKKVVvLIDEYEEN 73 55555556666666655556666666666677677889******************999999854 PP >> RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.1 6.9e-05 0.23 36 68 .. 130 163 .. 64 164 .. 0.78 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 6.9e-05 xxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx RF RNA_pol_L 36 ntdkdklifevetdgsl.kPeealkeAlkiLkek 68 n+ k +i+e +++ s+ k ee+ keAlk +++k 23726_FusoPortal_Gene_360 130 NKSKRAFIMEFKSTDSVeKLEEISKEALKQIEDK 163 588999********99978***********9987 PP >> PYRIN PAAD/DAPIN/Pyrin domain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 1.7 5.9e-05 0.2 5 30 .. 19 39 .. 16 73 .. 0.65 2 ? 1.1 0.2 0.13 4.4e+02 4 17 .. 147 160 .. 146 165 .. 0.85 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 5.9e-05 PYRIN 5 yLeeLseeefkkFKslLkeeeglksi 30 +L+eL+e++ +kFK+ L ee 23726_FusoPortal_Gene_360 19 LLKELNENDYSKFKKVLSEE-----A 39 4****************663.....2 PP == domain 2 score: 1.1 bits; conditional E-value: 0.13 PYRIN 4 lyLeeLseeefkkF 17 ++Lee+s+e +k++ 23726_FusoPortal_Gene_360 147 EKLEEISKEALKQI 160 579******99986 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (188 residues searched) Target model(s): 16712 (2907032 nodes) Passed MSV filter: 1322 (0.0791048); expected 334.2 (0.02) Passed bias filter: 516 (0.030876); expected 334.2 (0.02) Passed Vit filter: 46 (0.00275251); expected 16.7 (0.001) Passed Fwd filter: 5 (0.000299186); expected 0.2 (1e-05) Initial search space (Z): 16712 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.24u 0.23s 00:00:00.47 Elapsed: 00:00:00.30 # Mc/sec: 1821.74 // [ok]