1_1_36S_FusoPortal_Gene_105

Protein

1_1_36S_FusoPortal_Gene_105

Length

274 amino acids

Protein family membership

Ketopantoate hydroxymethyltransferase (IPR003700)

Homologous superfamilies

Homologous superfamily
3 - 264
Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (IPR015813)

1 50 100 150 200 274

Domains and repeats

None predicted.

Detailed signature matches

IPR015813

Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily
1. SSF51621 (Phosphoen...)
  
  3 - 264
  
  SUPERFAMILY
  SSF51621 (Phosphoenolpyruvate/pyruvate domain)
IPR003700

Ketopantoate hydroxymethyltransferase
1. MF_00156 (PanB)
  
  3 - 264
  
  HAMAP
  MF_00156 (PanB)
2. PIRSF000388 (PanB)
  
  1 - 267
  
  PIRSF
  PIRSF000388 (PanB)
3. PTHR20881 (3-METHYL...)
  
  2 - 269
  
  PANTHER
  PTHR20881 (3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE)
4. TIGR00222
  
  1 - 265
  
  TIGRFAMs
  TIGR00222 (TIGR00222)
5. cd06557 (KPHMT-like)
  
  5 - 258
  
  CDD
  cd06557 (KPHMT-like)
6. PF02548 (Pantoate_t...)
  
  3 - 260
  
  Pfam
  PF02548 (Pantoate_transf)

no IPR

Unintegrated signatures

G3DSA:3.20.20.60

1 - 264

GENE3D
G3DSA:3.20.20.60 (G3DSA:3.20.20.60)
PTHR20881:SF0 (3-ME...)

2 - 269

PANTHER
PTHR20881:SF0 (3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE)

Residue annotation

oligomerization in...

5V

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

6L

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

25D

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

26Y

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

27S

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

28M

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

31L

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

46L

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

48M

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

49V

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

50M

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

51L

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

52G

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

53Y

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

57I

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

58R

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

63D

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

66H

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

67H

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

70A

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

73R

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

86F

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

87L

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

97V

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

101G

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

104V

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

105Q

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

110N

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

128V

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

129A

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

130A

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

131K

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

132I

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

133P

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

143Q

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

144A

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

146N

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

147A

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

148L

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

149G

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

177F

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

217H

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

220L

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

221G

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

235A

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

238G

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

239E

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

240Q

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

241V

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)

242V

oligomerization interface
5V, 6L, 25D, 26Y, 27S, 28M, 31L, 46L, 48M, 49V, 50M, 51L, 52G, 53Y, 57I, 58R, 63D, 66H, 67H, 70A, 73R, 86F, 87L, 97V, 101G, 104V, 105Q, 110N, 128V, 129A, 130A, 131K, 132I, 133P, 143Q, 144A, 146N, 147A, 148L, 149G, 177F, 217H, 220L, 221G, 235A, 238G, 239E, 240Q, 241V, 242V
CDD
cd06557 (KPHMT-like)
active site cd06557

22T

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

41L

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

43G

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

44D

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

45S

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

83D

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

113K

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

137H

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

142P

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

182E

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

213V

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)

215V

active site
22T, 41L, 43G, 44D, 45S, 83D, 113K, 137H, 142P, 182E, 213V, 215V
CDD
cd06557 (KPHMT-like)
metal binding site...

44D

metal binding site
44D, 83D, 113K
CDD
cd06557 (KPHMT-like)

83D

metal binding site
44D, 83D, 113K
CDD
cd06557 (KPHMT-like)

113K

metal binding site
44D, 83D, 113K
CDD
cd06557 (KPHMT-like)

GO term prediction

Biological Process

GO:0015940 pantothenate biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_105

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component