1_1_36S_FusoPortal_Gene_1103

Protein

1_1_36S_FusoPortal_Gene_1103

Length

262 amino acids

Protein family membership

Crotonase superfamily (IPR001753)

Homologous superfamilies

Homologous superfamily
7 - 260
ClpP/crotonase-like domain superfamily (IPR029045)
Homologous superfamily
220 - 262
Crontonase, C-terminal (IPR014748)

1 50 100 150 200 262

Domains and repeats

None predicted.

Detailed signature matches

IPR029045

ClpP/crotonase-like domain superfamily
1. SSF52096 (ClpP/crot...)
  
  7 - 260
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
IPR014748

Crontonase, C-terminal
1. G3DSA:1.10.12.10
  
  220 - 262
  
  GENE3D
  G3DSA:1.10.12.10 (G3DSA:1.10.12.10)
IPR001753

Crotonase superfamily
1. PF00378 (ECH_1)
  
  14 - 261
  
  Pfam
  PF00378 (ECH_1)
IPR018376

Enoyl-CoA hydratase/isomerase, conserved site
1. PS00166 (ENOYL_COA_...)
  
  103 - 123
  
  PROSITE patterns
  PS00166 (ENOYL_COA_HYDRATASE)

no IPR

Unintegrated signatures

G3DSA:3.90.22...

8 - 219

GENE3D
G3DSA:3.90.226.10 (G3DSA:3.90.226.10)
PTHR11941 (ENOYL-CO...)

15 - 257

PANTHER
PTHR11941 (ENOYL-COA HYDRATASE-RELATED)
PTHR11941:SF54 (ENO...)

15 - 257

PANTHER
PTHR11941:SF54 (ENOYL-COA HYDRATASE, MITOCHONDRIAL)
cd06558 (crotonase-...)

9 - 201

CDD
cd06558 (crotonase-like)

Residue annotation

substrate binding ...

28M

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

30A

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

62K

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

66A

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

67G

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

68A

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

69D

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

70I

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

109Y

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

111L

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

112G

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

113G

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

135P

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

136E

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)

139L

substrate binding site
28M, 30A, 62K, 66A, 67G, 68A, 69D, 70I, 109Y, 111L, 112G, 113G, 135P, 136E, 139L
CDD
cd06558 (crotonase-like)
oxyanion hole (OAH...

68A

oxyanion hole (OAH) forming residues
68A, 113G
CDD
cd06558 (crotonase-like)

113G

oxyanion hole (OAH) forming residues
68A, 113G
CDD
cd06558 (crotonase-like)
trimer interface c...

93N

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

101P

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

122D

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

123L

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

124R

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

125I

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

137V

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

138N

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

139L

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

140G

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

146G

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

148T

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

149Q

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

150R

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

152S

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

153R

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

158G

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

159R

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

161K

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

162E

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

164I

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

165Y

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

168R

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

179G

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

182N

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

197M

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

200T

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

201I

trimer interface
93N, 101P, 122D, 123L, 124R, 125I, 137V, 138N, 139L, 140G, 146G, 148T, 149Q, 150R, 152S, 153R, 158G, 159R, 161K, 162E, 164I, 165Y, 168R, 179G, 182N, 197M, 200T, 201I
CDD
cd06558 (crotonase-like)

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_1103

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component