1_1_36S_FusoPortal_Gene_1258

Protein

1_1_36S_FusoPortal_Gene_1258

Length

490 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
9 - 288
Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (IPR015421)
345 - 490
Orn/Lys/Arg decarboxylase, C-terminal domain superfamily (IPR036633)
Homologous superfamily
17 - 390
Pyridoxal phosphate-dependent transferase (IPR015424)

1 50 100 150 200 250 300 350 400 450 490

Domains and repeats

Domain
9 - 374
Orn/Lys/Arg decarboxylase, major domain (IPR000310)
396 - 477
Orn/Lys/Arg decarboxylase, C-terminal (IPR008286)

1 50 100 150 200 250 300 350 400 450 490

Detailed signature matches

IPR015421

Pyridoxal phosphate-dependent transferase, major region, subdomain 1
1. G3DSA:3.40.64...
  
  9 - 288
  
  GENE3D
  G3DSA:3.40.640.10 (G3DSA:3.40.640.10)
IPR015424

Pyridoxal phosphate-dependent transferase
1. SSF53383 (PLP-depen...)
  
  17 - 390
  
  SUPERFAMILY
  SSF53383 (PLP-dependent transferases)
IPR036633

Orn/Lys/Arg decarboxylase, C-terminal domain superfamily
1. G3DSA:3.90.10...
  
  376 - 490
  
  GENE3D
  G3DSA:3.90.100.10 (G3DSA:3.90.100.10)
2. SSF55904 (Ornithine...)
  
  345 - 488
  
  SUPERFAMILY
  SSF55904 (Ornithine decarboxylase C-terminal domain)
IPR000310

Orn/Lys/Arg decarboxylase, major domain
1. cd00615 (Orn_deC_like)
  
  10 - 304
  
  CDD
  cd00615 (Orn_deC_like)
2. PF01276 (OKR_DC_1)
  
  9 - 374
  
  Pfam
  PF01276 (OKR_DC_1)
IPR008286

Orn/Lys/Arg decarboxylase, C-terminal
1. PF03711 (OKR_DC_1_C)
  
  396 - 477
  
  Pfam
  PF03711 (OKR_DC_1_C)

no IPR

Unintegrated signatures

PTHR43277 (FAMILY N...)

1 - 489

PANTHER
PTHR43277 (FAMILY NOT NAMED)
PTHR43277:SF2 (SUBF...)

1 - 489

PANTHER
PTHR43277:SF2 (SUBFAMILY NOT NAMED)

Residue annotation

homodimer interfac...

54D

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

58F

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

66H

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

91V

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

92N

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

93G

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

95S

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

96G

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

99Q

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

103M

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

104S

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

105V

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

107N

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

108P

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

119H

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

120K

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

229H

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

230K

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

233G

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

234A

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

235L

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

236T

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

237Q

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

255E

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

256I

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

258S

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

259M

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

260L

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

262T

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

269L

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

272S

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

275C

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

287L

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)

288L

homodimer interface
54D, 58F, 66H, 91V, 92N, 93G, 95S, 96G, 99Q, 103M, 104S, 105V, 107N, 108P, 119H, 120K, 229H, 230K, 233G, 234A, 235L, 236T, 237Q, 255E, 256I, 258S, 259M, 260L, 262T, 269L, 272S, 275C, 287L, 288L
CDD
cd00615 (Orn_deC_like)
pyridoxal 5'-phosp...

93G

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

94T

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

95S

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

119H

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

121S

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

171I

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

199D

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

201A

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

202H

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

227S

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

229H

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)

230K

pyridoxal 5'-phosphate binding site
93G, 94T, 95S, 119H, 121S, 171I, 199D, 201A, 202H, 227S, 229H, 230K
CDD
cd00615 (Orn_deC_like)
catalytic residue ...

230K

catalytic residue
230K
CDD
cd00615 (Orn_deC_like)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_1258

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component