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Entry type
Status
Per-residue features
Colour by
1_1_36S_FusoPortal_Gene_1541
Length
338 amino acids
Protein family membership
- Phosphoribosylformylglycinamidine cyclo-ligase (IPR004733)
Homologous superfamilies
-
Homologous superfamily3 - 165
- PurM-like, N-terminal domain superfamily (IPR036921)
166 - 335- PurM-like, C-terminal domain superfamily (IPR036676)
1
50
100
150
200
250
300
338
Domains and repeats
-
Domain56 - 159
- PurM-like, N-terminal domain (IPR016188)
171 - 333- PurM-like, C-terminal domain (IPR010918)
1
50
100
150
200
250
300
338
Detailed signature matches
Residue annotation
-
dimerization inter...41Fdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)42Gdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)43Adimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)44Mdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)45Ydimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)54Vdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)55Ldimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)56Vdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)57Sdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)59Tdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)61Gdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)67Edimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)89Ddimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)93Hdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)99Fdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)102Ddimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)105Adimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)136Edimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)140Mdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)142Gdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)149Ydimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)150Ddimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)154Fdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM)254Rdimerization interface
41F, 42G, 43A, 44M, 45Y, 54V, 55L, 56V, 57S, 59T, 61G, 67E, 89D, 93H, 99F, 102D, 105A, 136E, 140M, 142G, 149Y, 150D, 154F, 254R
CDD
cd02196 (PurM) -
putative ATP bindi...
GO term prediction
Biological Process
GO:0006189 'de novo' IMP biosynthetic process
Molecular Function
GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity
Cellular Component
GO:0005737 cytoplasm