1_1_36S_FusoPortal_Gene_1589

Protein

1_1_36S_FusoPortal_Gene_1589

Length

454 amino acids

Protein family membership

Fumarate lyase family (IPR000362)

Homologous superfamilies

Homologous superfamily
13 - 442
L-Aspartase-like (IPR008948)
Homologous superfamily
13 - 106
Fumarase/histidase, N-terminal (IPR024083)

1 50 100 150 200 250 300 350 400 454

Domains and repeats

Domain
20 - 299
Fumarate lyase, N-terminal (IPR022761)

1 50 100 150 200 250 300 350 400 454

Detailed signature matches

IPR024083

Fumarase/histidase, N-terminal
1. G3DSA:1.10.27...
  
  13 - 106
  
  GENE3D
  G3DSA:1.10.275.10 (G3DSA:1.10.275.10)
IPR008948

L-Aspartase-like
1. SSF48557 (L-asparta...)
  
  13 - 442
  
  SUPERFAMILY
  SSF48557 (L-aspartase-like)
IPR000362

Fumarate lyase family
1. PR00149 (FUMRATELYASE)
  
  147 - 165
  
  PRINTS
  PR00149 (FUMRATELYASE)
  
  232 - 259
  
  PRINTS
  PR00149 (FUMRATELYASE)
  
  276 - 292
  
  PRINTS
  PR00149 (FUMRATELYASE)
  
  102 - 120
  
  PRINTS
  PR00149 (FUMRATELYASE)
IPR022761

Fumarate lyase, N-terminal
1. PF00206 (Lyase_1)
  
  20 - 299
  
  Pfam
  PF00206 (Lyase_1)
IPR020557

Fumarate lyase, conserved site
1. PS00163 (FUMARATE_L...)
  
  276 - 285
  
  PROSITE patterns
  PS00163 (FUMARATE_LYASES)

no IPR

Unintegrated signatures

Coil

168 - 188

COILS
Coil (Coil)
G3DSA:1.10.40.30

366 - 443

GENE3D
G3DSA:1.10.40.30 (G3DSA:1.10.40.30)
G3DSA:1.20.20...

107 - 361

GENE3D
G3DSA:1.20.200.10 (G3DSA:1.20.200.10)
PR00145 (ARGSUCLYASE)

232 - 256

PRINTS
PR00145 (ARGSUCLYASE)

276 - 292

PRINTS
PR00145 (ARGSUCLYASE)

101 - 123

PRINTS
PR00145 (ARGSUCLYASE)

142 - 162

PRINTS
PR00145 (ARGSUCLYASE)
PTHR43093 (FAMILY N...)

9 - 445

PANTHER
PTHR43093 (FAMILY NOT NAMED)
cd01597 (pCLME)

12 - 443

CDD
cd01597 (pCLME)

Residue annotation

tetramer interface...

24F

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

25D

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

26E

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

29R

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

30F

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

73S

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

76Y

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

77A

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

100N

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

101Y

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

153R

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

154S

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

155H

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

157Q

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

158Y

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

160V

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

161P

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

167K

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

169A

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

174E

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

177R

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

180E

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

181R

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

184S

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

198T

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

199G

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

200S

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

203L

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

208G

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

209I

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

224S

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

225N

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

230N

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

231S

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

233D

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

234S

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

236G

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

237E

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

240S

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

243A

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

244L

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

251K

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

254G

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

255E

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

260G

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

261K

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

263D

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

284K

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

285N

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

290E

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

297Y

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

298H

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

303V

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

307L

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

312H

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

313E

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

314H

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

315E

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

316R

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

322W

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

323A

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

325W

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

327A

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

366D

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

433G

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

434I

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

438I

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)

441E

tetramer interface
24F, 25D, 26E, 29R, 30F, 73S, 76Y, 77A, 100N, 101Y, 153R, 154S, 155H, 157Q, 158Y, 160V, 161P, 167K, 169A, 174E, 177R, 180E, 181R, 184S, 198T, 199G, 200S, 203L, 208G, 209I, 224S, 225N, 230N, 231S, 233D, 234S, 236G, 237E, 240S, 243A, 244L, 251K, 254G, 255E, 260G, 261K, 263D, 284K, 285N, 290E, 297Y, 298H, 303V, 307L, 312H, 313E, 314H, 315E, 316R, 322W, 323A, 325W, 327A, 366D, 433G, 434I, 438I, 441E
CDD
cd01597 (pCLME)
active site cd01597

81N

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

82S

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

107T

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

108T

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

109Q

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

154S

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

155H

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

197A

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

282H

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

283K

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

285N

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

316R

active site
81N, 82S, 107T, 108T, 109Q, 154S, 155H, 197A, 282H, 283K, 285N, 316R
CDD
cd01597 (pCLME)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_1589

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component