1_1_36S_FusoPortal_Gene_1591

Protein

1_1_36S_FusoPortal_Gene_1591

Length

456 amino acids

Protein family membership

Fumarate lyase family (IPR000362)

Homologous superfamilies

Homologous superfamily
7 - 109
Fumarase/histidase, N-terminal (IPR024083)
Homologous superfamily
13 - 447
L-Aspartase-like (IPR008948)

1 50 100 150 200 250 300 350 400 456

Domains and repeats

Domain
20 - 299
Fumarate lyase, N-terminal (IPR022761)
371 - 440
Adenylosuccinate lyase C-terminal (IPR019468)

1 50 100 150 200 250 300 350 400 456

Detailed signature matches

IPR024083

Fumarase/histidase, N-terminal
1. G3DSA:1.10.27...
  
  7 - 109
  
  GENE3D
  G3DSA:1.10.275.10 (G3DSA:1.10.275.10)
IPR008948

L-Aspartase-like
1. SSF48557 (L-asparta...)
  
  13 - 447
  
  SUPERFAMILY
  SSF48557 (L-aspartase-like)
IPR000362

Fumarate lyase family
1. PR00149 (FUMRATELYASE)
  
  150 - 168
  
  PRINTS
  PR00149 (FUMRATELYASE)
  
  280 - 296
  
  PRINTS
  PR00149 (FUMRATELYASE)
  
  235 - 262
  
  PRINTS
  PR00149 (FUMRATELYASE)
  
  105 - 123
  
  PRINTS
  PR00149 (FUMRATELYASE)
IPR022761

Fumarate lyase, N-terminal
1. PF00206 (Lyase_1)
  
  20 - 299
  
  Pfam
  PF00206 (Lyase_1)
IPR019468

Adenylosuccinate lyase C-terminal
1. PF10397 (ADSL_C)
  
  371 - 440
  
  Pfam
  PF10397 (ADSL_C)
IPR020557

Fumarate lyase, conserved site
1. PS00163 (FUMARATE_L...)
  
  280 - 289
  
  PROSITE patterns
  PS00163 (FUMARATE_LYASES)

no IPR

Unintegrated signatures

Coil

350 - 370

COILS
Coil (Coil)

124 - 147

COILS
Coil (Coil)
G3DSA:1.10.40.30

381 - 442

GENE3D
G3DSA:1.10.40.30 (G3DSA:1.10.40.30)
G3DSA:1.20.20...

110 - 380

GENE3D
G3DSA:1.20.200.10 (G3DSA:1.20.200.10)
PR00145 (ARGSUCLYASE)

145 - 165

PRINTS
PR00145 (ARGSUCLYASE)

280 - 296

PRINTS
PR00145 (ARGSUCLYASE)

235 - 259

PRINTS
PR00145 (ARGSUCLYASE)
PTHR43093 (FAMILY N...)

7 - 446

PANTHER
PTHR43093 (FAMILY NOT NAMED)
cd01597 (pCLME)

14 - 439

CDD
cd01597 (pCLME)

Residue annotation

tetramer interface...

27F

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

28D

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

29D

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

32R

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

33M

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

76K

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

79I

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

80E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

103N

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

104Y

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

156R

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

157T

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

158H

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

160Q

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

161Q

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

163L

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

164P

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

170K

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

172A

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

177E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

180R

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

183E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

184R

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

187R

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

201V

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

202G

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

203T

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

206A

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

211G

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

212H

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

227P

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

228E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

233S

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

234C

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

236D

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

237R

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

239I

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

240E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

243F

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

246T

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

247S

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

254K

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

257N

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

258E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

263N

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

264K

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

266E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

288R

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

289N

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

294E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

301K

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

302L

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

307F

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

311L

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

316L

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

317E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

318H

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

319E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

320R

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

326R

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

327T

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

329W

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

331S

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

370K

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

433G

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

434E

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)

438I

tetramer interface
27F, 28D, 29D, 32R, 33M, 76K, 79I, 80E, 103N, 104Y, 156R, 157T, 158H, 160Q, 161Q, 163L, 164P, 170K, 172A, 177E, 180R, 183E, 184R, 187R, 201V, 202G, 203T, 206A, 211G, 212H, 227P, 228E, 233S, 234C, 236D, 237R, 239I, 240E, 243F, 246T, 247S, 254K, 257N, 258E, 263N, 264K, 266E, 288R, 289N, 294E, 301K, 302L, 307F, 311L, 316L, 317E, 318H, 319E, 320R, 326R, 327T, 329W, 331S, 370K, 433G, 434E, 438I
CDD
cd01597 (pCLME)
active site cd01597

84H

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

85S

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

110T

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

111T

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

112Q

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

157T

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

158H

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

200G

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

286H

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

287K

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

289N

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

320R

active site
84H, 85S, 110T, 111T, 112Q, 157T, 158H, 200G, 286H, 287K, 289N, 320R
CDD
cd01597 (pCLME)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_1591

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component