1_1_36S_FusoPortal_Gene_1904

Protein

1_1_36S_FusoPortal_Gene_1904

Length

331 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
103 - 301
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 250 300 331

Domains and repeats

Domain
7 - 330
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (IPR006139)
Domain
112 - 299
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (IPR006140)

1 50 100 150 200 250 300 331

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  103 - 301
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR006139

D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
1. PF00389 (2-Hacid_dh)
  
  7 - 330
  
  Pfam
  PF00389 (2-Hacid_dh)
IPR006140

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
1. PF02826 (2-Hacid_dh_C)
  
  112 - 299
  
  Pfam
  PF02826 (2-Hacid_dh_C)
IPR029752

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1
1. PS00065 (D_2_HYDROX...)
  
  149 - 176
  
  PROSITE patterns
  PS00065 (D_2_HYDROXYACID_DH_1)
IPR029753

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site
1. PS00671 (D_2_HYDROX...)
  
  224 - 240
  
  PROSITE patterns
  PS00671 (D_2_HYDROXYACID_DH_3)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

117 - 302

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)

1 - 116

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PTHR43026 (FAMILY N...)

1 - 331

PANTHER
PTHR43026 (FAMILY NOT NAMED)
PTHR43026:SF2 (SUBF...)

1 - 331

PANTHER
PTHR43026:SF2 (SUBFAMILY NOT NAMED)
SSF52283 (Formate/g...)

2 - 138

SUPERFAMILY
SSF52283 (Formate/glycerate dehydrogenase catalytic domain-like)
cd12184 (HGDH_like)

1 - 330

CDD
cd12184 (HGDH_like)

Residue annotation

putative homodimer...

52R

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

102S

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

104N

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

105A

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

108E

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

109L

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

112S

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

115M

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

116S

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

119R

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

124T

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

125G

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

128T

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

140F

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

141S

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

143E

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

144V

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

145R

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

146N

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

164L

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

167G

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

168L

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

267L

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

268F

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

294I

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

296P

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

297H

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

298V

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

299G

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

300S

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

301Y

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

302T

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

303D

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

304E

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)

306A

putative homodimer interface
52R, 102S, 104N, 105A, 108E, 109L, 112S, 115M, 116S, 119R, 124T, 125G, 128T, 140F, 141S, 143E, 144V, 145R, 146N, 164L, 167G, 168L, 267L, 268F, 294I, 296P, 297H, 298V, 299G, 300S, 301Y, 302T, 303D, 304E, 306A
CDD
cd12184 (HGDH_like)
putative ligand bi...

77T

putative ligand binding site
77T, 78V, 79G, 101Y, 235R, 297H, 300S
CDD
cd12184 (HGDH_like)

78V

putative ligand binding site
77T, 78V, 79G, 101Y, 235R, 297H, 300S
CDD
cd12184 (HGDH_like)

79G

putative ligand binding site
77T, 78V, 79G, 101Y, 235R, 297H, 300S
CDD
cd12184 (HGDH_like)

101Y

putative ligand binding site
77T, 78V, 79G, 101Y, 235R, 297H, 300S
CDD
cd12184 (HGDH_like)

235R

putative ligand binding site
77T, 78V, 79G, 101Y, 235R, 297H, 300S
CDD
cd12184 (HGDH_like)

297H

putative ligand binding site
77T, 78V, 79G, 101Y, 235R, 297H, 300S
CDD
cd12184 (HGDH_like)

300S

putative ligand binding site
77T, 78V, 79G, 101Y, 235R, 297H, 300S
CDD
cd12184 (HGDH_like)
putative NAD bindi...

101Y

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

106I

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

153G

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

155G

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

156R

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

157I

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

158G

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

175Y

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

176D

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

177L

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

205H

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

206A

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

207P

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

208Y

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

212N

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

215V

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

233T

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

234G

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

235R

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

259D

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

260T

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

297H

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

299G

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)

300S

putative NAD binding site
101Y, 106I, 153G, 155G, 156R, 157I, 158G, 175Y, 176D, 177L, 205H, 206A, 207P, 208Y, 212N, 215V, 233T, 234G, 235R, 259D, 260T, 297H, 299G, 300S
CDD
cd12184 (HGDH_like)
catalytic site cd1...

235R

catalytic site
235R, 264E, 297H
CDD
cd12184 (HGDH_like)

264E

catalytic site
235R, 264E, 297H
CDD
cd12184 (HGDH_like)

297H

catalytic site
235R, 264E, 297H
CDD
cd12184 (HGDH_like)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_1904

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component