1_1_36S_FusoPortal_Gene_2077

Protein

1_1_36S_FusoPortal_Gene_2077

Length

352 amino acids

Protein family membership

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic (IPR017846)

Homologous superfamilies

Homologous superfamily
5 - 71
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal (IPR023195)
Homologous superfamily
6 - 338
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily (IPR036087)

1 50 100 150 200 250 300 352

Domains and repeats

Domain
12 - 341
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like (IPR003200)

1 50 100 150 200 250 300 352

Detailed signature matches

IPR023195

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal
1. G3DSA:1.10.16...
  
  5 - 71
  
  GENE3D
  G3DSA:1.10.1610.10 (G3DSA:1.10.1610.10)
IPR036087

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily
1. SSF52733 (Nicotinat...)
  
  6 - 338
  
  SUPERFAMILY
  SSF52733 (Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT))
IPR017846

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic
1. TIGR03160
  
  17 - 344
  
  TIGRFAMs
  TIGR03160 (TIGR03160)
IPR003200

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like
1. cd02439 (DMB-PRT_CobT)
  
  31 - 341
  
  CDD
  cd02439 (DMB-PRT_CobT)
2. PF02277 (DBI_PRT)
  
  12 - 341
  
  Pfam
  PF02277 (DBI_PRT)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

72 - 330

GENE3D
G3DSA:3.40.50.10210 (G3DSA:3.40.50.10210)
PTHR43463 (FAMILY N...)

4 - 343

PANTHER
PTHR43463 (FAMILY NOT NAMED)
PTHR43463:SF1 (NICO...)

4 - 343

PANTHER
PTHR43463:SF1 (NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE)

Residue annotation

putative dimer int...

31K

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

32P

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

33E

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

34G

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

35S

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

36L

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

37G

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

38V

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

39L

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

78S

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

83Y

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

86L

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

87V

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

95M

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

96A

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

97T

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

100I

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

101F

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

103K

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

293E

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

307S

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

309F

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

310L

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

311Q

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

312M

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

313K

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

314M

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

316L

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

324L

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

327P

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

331C

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

334A

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

335M

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

339L

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)

340R

putative dimer interface
31K, 32P, 33E, 34G, 35S, 36L, 37G, 38V, 39L, 78S, 83Y, 86L, 87V, 95M, 96A, 97T, 100I, 101F, 103K, 293E, 307S, 309F, 310L, 311Q, 312M, 313K, 314M, 316L, 324L, 327P, 331C, 334A, 335M, 339L, 340R
CDD
cd02439 (DMB-PRT_CobT)
active site pocket...

32P

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

33E

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

77S

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

83Y

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

87V

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

175E

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

176M

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

177G

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

178I

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

179G

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

180N

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

181T

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

265G

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

266F

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

267I

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

292S

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

316L

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

317G

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

318E

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)

341T

active site pocket
32P, 33E, 77S, 83Y, 87V, 175E, 176M, 177G, 178I, 179G, 180N, 181T, 265G, 266F, 267I, 292S, 316L, 317G, 318E, 341T
CDD
cd02439 (DMB-PRT_CobT)
putative cataytic ...

318E

putative cataytic base
318E
CDD
cd02439 (DMB-PRT_CobT)

GO term prediction

Biological Process

GO:0009163 nucleoside biosynthetic process
GO:0009236 cobalamin biosynthetic process

Molecular Function

GO:0008939 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_2077

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component