1_1_36S_FusoPortal_Gene_395

Protein

1_1_36S_FusoPortal_Gene_395

Length

1,322 amino acids

Protein family membership

DNA-directed RNA polymerase, subunit beta-prime (IPR012754)

Homologous superfamilies

None predicted.

Domains and repeats

Domain
4 - 331
RNA polymerase Rpb1, domain 1 (IPR007080)
333 - 474
RNA polymerase, alpha subunit (IPR000722)
478 - 618
RNA polymerase Rpb1, domain 3 (IPR007066)
650 - 715
RNA polymerase Rpb1, domain 4 (IPR007083)
725 - 1,249
RNA polymerase Rpb1, domain 5 (IPR007081)

1 200 400 600 800 1000 1200 1322

Detailed signature matches

IPR012754

DNA-directed RNA polymerase, subunit beta-prime
1. MF_01322 (RNApol_ba...)
  
  3 - 1,313
  
  HAMAP
  MF_01322 (RNApol_bact_RpoC)
2. TIGR02386
  
  8 - 1,303
  
  TIGRFAMs
  TIGR02386 (TIGR02386)
IPR007080

RNA polymerase Rpb1, domain 1
1. PF04997 (RNA_pol_Rp...)
  
  4 - 331
  
  Pfam
  PF04997 (RNA_pol_Rpb1_1)
IPR000722

RNA polymerase, alpha subunit
1. PF00623 (RNA_pol_Rp...)
  
  333 - 474
  
  Pfam
  PF00623 (RNA_pol_Rpb1_2)
IPR007066

RNA polymerase Rpb1, domain 3
1. PF04983 (RNA_pol_Rp...)
  
  478 - 618
  
  Pfam
  PF04983 (RNA_pol_Rpb1_3)
IPR007083

RNA polymerase Rpb1, domain 4
1. PF05000 (RNA_pol_Rp...)
  
  650 - 715
  
  Pfam
  PF05000 (RNA_pol_Rpb1_4)
IPR007081

RNA polymerase Rpb1, domain 5
1. PF04998 (RNA_pol_Rp...)
  
  725 - 1,249
  
  Pfam
  PF04998 (RNA_pol_Rpb1_5)

no IPR

Unintegrated signatures

Coil

176 - 210

COILS
Coil (Coil)

376 - 396

COILS
Coil (Coil)
G3DSA:2.40.40.20

335 - 477

GENE3D
G3DSA:2.40.40.20 (G3DSA:2.40.40.20)
G3DSA:2.40.50...

989 - 1,058

GENE3D
G3DSA:2.40.50.100 (G3DSA:2.40.50.100)

962 - 988

GENE3D
G3DSA:2.40.50.100 (G3DSA:2.40.50.100)

1,061 - 1,150

GENE3D
G3DSA:2.40.50.100 (G3DSA:2.40.50.100)

863 - 961

GENE3D
G3DSA:2.40.50.100 (G3DSA:2.40.50.100)
PTHR19376 (DNA-DIRE...)

6 - 1,304

PANTHER
PTHR19376 (DNA-DIRECTED RNA POLYMERASE)
SSF64484 (beta and ...)

1,067 - 1,302

SUPERFAMILY
SSF64484 (beta and beta-prime subunits of DNA dependent RNA-polymerase)

5 - 901

SUPERFAMILY
SSF64484 (beta and beta-prime subunits of DNA dependent RNA-polymerase)
cd01609 (RNAP_beta'_N)

5 - 772

CDD
cd01609 (RNAP_beta'_N)
cd02655 (RNAP_beta'_C)

864 - 1,299

CDD
cd02655 (RNAP_beta'_C)

Residue annotation

beta and beta' int...

5N

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

6F

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

7E

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

8K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

9I

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

10K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

11I

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

12K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

14A

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

18K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

21E

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

22W

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

23S

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

24Y

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

36R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

38L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

55K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

66R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

85K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

86V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

88R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

89E

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

90R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

91M

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

102H

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

104W

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

228L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

232P

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

234I

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

237D

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

238L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

240P

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

242V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

245D

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

246G

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

296I

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

316L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

319M

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

320L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

326R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

327F

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

328R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

329Q

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

330N

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

331L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

332L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

333G

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

334K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

335R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

336V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

337D

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

338Y

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

339S

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

340A

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

341R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

342S

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

343V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

344I

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

345V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

346V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

348P

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

360K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

361M

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

364E

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

365L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

368P

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

369F

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

371M

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

372R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

387K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

413N

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

417T

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

420R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

421L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

423I

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

424Q

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

434K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

435A

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

440P

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

449D

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

450F

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

451D

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

454Q

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

458H

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

459L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

460M

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

461L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

462S

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

463P

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

464E

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

465A

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

468E

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

472L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

473M

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

478N

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

492S

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

493Q

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

494D

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

497M

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

501Y

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

537V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

603Y

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

604H

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

606S

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

607T

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

608L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

609A

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

610G

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

611I

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

612S

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

613V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

614G

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

615V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

616E

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

617D

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

678F

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

684M

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

690R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

695Q

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

698Q

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

699L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

703R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

708D

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

709T

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

716T

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

722F

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

723R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

724E

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

725G

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

726L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

727T

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

728V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

729L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

731F

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

732F

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

735S

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

736H

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

738A

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

739R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

740K

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

742L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

743A

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

744D

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

746A

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

747L

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

757R

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)

760V

beta and beta' interface
5N, 6F, 7E, 8K, 9I, 10K, 11I, 12K, 14A, 18K, 21E, 22W, 23S, 24Y, 36R, 38L, 55K, 66R, 85K, 86V, 88R, 89E, 90R, 91M, 102H, 104W, 228L, 232P, 234I, 237D, 238L, 240P, 242V, 245D, 246G, 296I, 316L, 319M, 320L, 326R, 327F, 328R, 329Q, 330N, 331L, 332L, 333G, 334K, 335R, 336V, 337D, 338Y, 339S, 340A, 341R, 342S, 343V, 344I, 345V, 346V, 348P, 360K, 361M, 364E, 365L, 368P, 369F, 371M, 372R, 387K, 413N, 417T, 420R, 421L, 423I, 424Q, 434K, 435A, 440P, 449D, 450F, 451D, 454Q, 458H, 459L, 460M, 461L, 462S, 463P, 464E, 465A, 468E, 472L, 473M, 478N, 492S, 493Q, 494D, 497M, 501Y, 537V, 603Y, 604H, 606S, 607T, 608L, 609A, 610G, 611I, 612S, 613V, 614G, 615V, 616E, 617D, 678F, 684M, 690R, 695Q, 698Q, 699L, 703R, 708D, 709T, 716T, 722F, 723R, 724E, 725G, 726L, 727T, 728V, 729L, 731F, 732F, 735S, 736H, 738A, 739R, 740K, 742L, 743A, 744D, 746A, 747L, 757R, 760V
CDD
cd01609 (RNAP_beta'_N)
beta' and sigma fa...

31E

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

32T

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

33I

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

35Y

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

54T

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

56D

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

66R

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

68R

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

84S

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

129Y

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

130F

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

240P

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

241M

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

244L

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

248R

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

249F

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

250A

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

251T

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

252S

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

253D

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

256D

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

259R

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

263N

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

264R

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

267R

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

269K

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

270K

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

271L

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

272L

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

276A

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

277P

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

278E

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

279I

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

280V

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

281V

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

282K

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

283N

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

284E

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

286R

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

287M

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

290E

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

301R

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

311R

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

314K

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

323K

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

324Q

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

386A

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

388K

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)

389L

beta' and sigma factor interface
31E, 32T, 33I, 35Y, 54T, 56D, 66R, 68R, 84S, 129Y, 130F, 240P, 241M, 244L, 248R, 249F, 250A, 251T, 252S, 253D, 256D, 259R, 263N, 264R, 267R, 269K, 270K, 271L, 272L, 276A, 277P, 278E, 279I, 280V, 281V, 282K, 283N, 284E, 286R, 287M, 290E, 301R, 311R, 314K, 323K, 324Q, 386A, 388K, 389L
CDD
cd01609 (RNAP_beta'_N)
Zn-binding cd01609

59C

Zn-binding
59C, 61C, 74C, 77C
CDD
cd01609 (RNAP_beta'_N)

61C

Zn-binding
59C, 61C, 74C, 77C
CDD
cd01609 (RNAP_beta'_N)

74C

Zn-binding
59C, 61C, 74C, 77C
CDD
cd01609 (RNAP_beta'_N)

77C

Zn-binding
59C, 61C, 74C, 77C
CDD
cd01609 (RNAP_beta'_N)
active site region...

110P

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

300R

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

323K

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

328R

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

335R

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

341R

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

414R

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

415A

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

416P

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

449D

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

451D

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

453D

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

749T

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

750A

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

753G

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)

754Y

active site region
110P, 300R, 323K, 328R, 335R, 341R, 414R, 415A, 416P, 449D, 451D, 453D, 749T, 750A, 753G, 754Y
CDD
cd01609 (RNAP_beta'_N)
catalytic site cd0...

449D

catalytic site
449D, 451D, 453D
CDD
cd01609 (RNAP_beta'_N)

451D

catalytic site
449D, 451D, 453D
CDD
cd01609 (RNAP_beta'_N)

453D

catalytic site
449D, 451D, 453D
CDD
cd01609 (RNAP_beta'_N)
Rpb1 (beta') - Rpb...

864K

Rpb1 (beta') - Rpb6 (omega) interaction site
864K, 867L, 868L, 870E, 1,297T
CDD
cd02655 (RNAP_beta'_C)

867L

Rpb1 (beta') - Rpb6 (omega) interaction site
864K, 867L, 868L, 870E, 1,297T
CDD
cd02655 (RNAP_beta'_C)

868L

Rpb1 (beta') - Rpb6 (omega) interaction site
864K, 867L, 868L, 870E, 1,297T
CDD
cd02655 (RNAP_beta'_C)

870E

Rpb1 (beta') - Rpb6 (omega) interaction site
864K, 867L, 868L, 870E, 1,297T
CDD
cd02655 (RNAP_beta'_C)

1,297T

Rpb1 (beta') - Rpb6 (omega) interaction site
864K, 867L, 868L, 870E, 1,297T
CDD
cd02655 (RNAP_beta'_C)
Rpb1 (beta') - Rpb...

874V

Rpb1 (beta') - Rpb2 (beta) interaction site
874V, 878Q, 1,277V, 1,283L, 1,289I, 1,292K, 1,293I, 1,297T
CDD
cd02655 (RNAP_beta'_C)

878Q

Rpb1 (beta') - Rpb2 (beta) interaction site
874V, 878Q, 1,277V, 1,283L, 1,289I, 1,292K, 1,293I, 1,297T
CDD
cd02655 (RNAP_beta'_C)

1,277V

Rpb1 (beta') - Rpb2 (beta) interaction site
874V, 878Q, 1,277V, 1,283L, 1,289I, 1,292K, 1,293I, 1,297T
CDD
cd02655 (RNAP_beta'_C)

1,283L

Rpb1 (beta') - Rpb2 (beta) interaction site
874V, 878Q, 1,277V, 1,283L, 1,289I, 1,292K, 1,293I, 1,297T
CDD
cd02655 (RNAP_beta'_C)

1,289I

Rpb1 (beta') - Rpb2 (beta) interaction site
874V, 878Q, 1,277V, 1,283L, 1,289I, 1,292K, 1,293I, 1,297T
CDD
cd02655 (RNAP_beta'_C)

1,292K

Rpb1 (beta') - Rpb2 (beta) interaction site
874V, 878Q, 1,277V, 1,283L, 1,289I, 1,292K, 1,293I, 1,297T
CDD
cd02655 (RNAP_beta'_C)

1,293I

Rpb1 (beta') - Rpb2 (beta) interaction site
874V, 878Q, 1,277V, 1,283L, 1,289I, 1,292K, 1,293I, 1,297T
CDD
cd02655 (RNAP_beta'_C)

1,297T

Rpb1 (beta') - Rpb2 (beta) interaction site
874V, 878Q, 1,277V, 1,283L, 1,289I, 1,292K, 1,293I, 1,297T
CDD
cd02655 (RNAP_beta'_C)
G-loop cd02655

889M

G-loop
889M, 890R, 891T, 892F, 893H, 894T, 895G, 896G, 897V
CDD
cd02655 (RNAP_beta'_C)

890R

G-loop
889M, 890R, 891T, 892F, 893H, 894T, 895G, 896G, 897V
CDD
cd02655 (RNAP_beta'_C)

891T

G-loop
889M, 890R, 891T, 892F, 893H, 894T, 895G, 896G, 897V
CDD
cd02655 (RNAP_beta'_C)

892F

G-loop
889M, 890R, 891T, 892F, 893H, 894T, 895G, 896G, 897V
CDD
cd02655 (RNAP_beta'_C)

893H

G-loop
889M, 890R, 891T, 892F, 893H, 894T, 895G, 896G, 897V
CDD
cd02655 (RNAP_beta'_C)

894T

G-loop
889M, 890R, 891T, 892F, 893H, 894T, 895G, 896G, 897V
CDD
cd02655 (RNAP_beta'_C)

895G

G-loop
889M, 890R, 891T, 892F, 893H, 894T, 895G, 896G, 897V
CDD
cd02655 (RNAP_beta'_C)

896G

G-loop
889M, 890R, 891T, 892F, 893H, 894T, 895G, 896G, 897V
CDD
cd02655 (RNAP_beta'_C)

897V

G-loop
889M, 890R, 891T, 892F, 893H, 894T, 895G, 896G, 897V
CDD
cd02655 (RNAP_beta'_C)
DNA binding site c...

1,082R

DNA binding site
1,082R, 1,247K, 1,262Q, 1,263E
CDD
cd02655 (RNAP_beta'_C)

1,247K

DNA binding site
1,082R, 1,247K, 1,262Q, 1,263E
CDD
cd02655 (RNAP_beta'_C)

1,262Q

DNA binding site
1,082R, 1,247K, 1,262Q, 1,263E
CDD
cd02655 (RNAP_beta'_C)

1,263E

DNA binding site
1,082R, 1,247K, 1,262Q, 1,263E
CDD
cd02655 (RNAP_beta'_C)

GO term prediction

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_395

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component