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Entry type
Status
Per-residue features
Colour by
1_1_36S_FusoPortal_Gene_427
Length
322 amino acids
Protein family membership
- tRNA-dihydrouridine synthase (IPR001269)
- tRNA-dihydrouridine synthase, TIM-barrel, NifR3 (IPR004652)
Homologous superfamilies
-
Homologous superfamily
1
50
100
150
200
250
322
Domains and repeats
-
Domain3 - 230
- DUS-like, FMN-binding domain (IPR035587)
1
50
100
150
200
250
322
Detailed signature matches
-
-
1 - 232
-
-
-
242 - 321
-
-
-
PTHR11082 (TRNA-DIH...)2 - 311
-
PIRSF006621 (Dus)1 - 319
-
PF01207 (Dus)6 - 309
-
-
-
PTHR11082:SF25 (TRN...)2 - 311
-
3 - 311
-
Residue annotation
-
FMN binding site c...7AFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)8PFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)9IFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)33MFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)60QFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)87NFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)131KFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)160HFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)191NFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)193DFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)215AFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN)216RFMN binding site
7A, 8P, 9I, 33M, 60Q, 87N, 131K, 160H, 191N, 193D, 215A, 216R
CDD
cd02801 (DUS_like_FMN) -
active site cd0280160Qactive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)90Cactive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)91Pactive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)131Kactive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)133Ractive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)159Vactive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)160Hactive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)162Ractive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)163Tactive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)192Gactive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)193Dactive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN)216Ractive site
60Q, 90C, 91P, 131K, 133R, 159V, 160H, 162R, 163T, 192G, 193D, 216R
CDD
cd02801 (DUS_like_FMN) -
catalytic residues...
-
substrate binding ...91P131K159V163T192G193D
GO term prediction
Biological Process
GO:0008033 tRNA processing
GO:0055114 oxidation-reduction process
Molecular Function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0017150 tRNA dihydrouridine synthase activity
GO:0050660 flavin adenine dinucleotide binding
Cellular Component
None predicted.