1_1_36S_FusoPortal_Gene_457

Protein

1_1_36S_FusoPortal_Gene_457

Length

229 amino acids

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)

Homologous superfamilies

Homologous superfamily
3 - 209
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 229

Domains and repeats

None predicted.

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  3 - 209
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR002347

Short-chain dehydrogenase/reductase SDR
1. PR00081 (GDHRDH)
  
  113 - 129
  
  PRINTS
  PR00081 (GDHRDH)
  
  187 - 207
  
  PRINTS
  PR00081 (GDHRDH)
  
  2 - 19
  
  PRINTS
  PR00081 (GDHRDH)
  
  160 - 177
  
  PRINTS
  PR00081 (GDHRDH)
  
  139 - 158
  
  PRINTS
  PR00081 (GDHRDH)
2. PF00106 (adh_short)
  
  3 - 178
  
  Pfam
  PF00106 (adh_short)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

1 - 217

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PTHR42879 (FAMILY N...)

3 - 212

PANTHER
PTHR42879 (FAMILY NOT NAMED)
cd05233 (SDR_c)

3 - 218

CDD
cd05233 (SDR_c)

Residue annotation

NAD(P) binding sit...

7G

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

9T

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

10S

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

11G

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

12I

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

31G

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

32R

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

33D

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

49C

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

50D

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

51L

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

75V

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

76A

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

77G

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

98V

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

124L

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

125S

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

126S

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

139Y

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

143K

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

169P

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

170D

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

171M

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

172T

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

174T

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)

175D

NAD(P) binding site
7G, 9T, 10S, 11G, 12I, 31G, 32R, 33D, 49C, 50D, 51L, 75V, 76A, 77G, 98V, 124L, 125S, 126S, 139Y, 143K, 169P, 170D, 171M, 172T, 174T, 175D
CDD
cd05233 (SDR_c)
active site cd05233

99N

active site
99N, 126S, 139Y, 143K
CDD
cd05233 (SDR_c)

126S

active site
99N, 126S, 139Y, 143K
CDD
cd05233 (SDR_c)

139Y

active site
99N, 126S, 139Y, 143K
CDD
cd05233 (SDR_c)

143K

active site
99N, 126S, 139Y, 143K
CDD
cd05233 (SDR_c)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_457

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component