1_1_36S_FusoPortal_Gene_499

Protein

1_1_36S_FusoPortal_Gene_499

Length

394 amino acids

Protein family membership

Peptidase M42 (IPR008007)

Peptidase M20/DapE, YgeY (IPR017706)

Peptidase M20 (IPR002933)

Homologous superfamilies

Homologous superfamily
174 - 283
Bacterial exopeptidase dimerisation domain (IPR036264)

1 50 100 150 200 250 300 350 394

Domains and repeats

Domain
171 - 278
Peptidase M20, dimerisation domain (IPR011650)

1 50 100 150 200 250 300 350 394

Detailed signature matches

IPR036264

Bacterial exopeptidase dimerisation domain
1. SSF55031 (Bacterial...)
  
  174 - 283
  
  SUPERFAMILY
  SSF55031 (Bacterial exopeptidase dimerisation domain)
IPR008007

Peptidase M42
1. PIRSF001123 (PepA_GA)
  
  91 - 212
  
  PIRSF
  PIRSF001123 (PepA_GA)
  
  7 - 79
  
  PIRSF
  PIRSF001123 (PepA_GA)
  
  309 - 359
  
  PIRSF
  PIRSF001123 (PepA_GA)
IPR017706

Peptidase M20/DapE, YgeY
1. cd05649 (M20_ArgE_D...)
  
  11 - 391
  
  CDD
  cd05649 (M20_ArgE_DapE_like4)
IPR002933

Peptidase M20
1. PF01546 (Peptidase_M20)
  
  69 - 389
  
  Pfam
  PF01546 (Peptidase_M20)
IPR011650

Peptidase M20, dimerisation domain
1. PF07687 (M20_dimer)
  
  171 - 278
  
  Pfam
  PF07687 (M20_dimer)
IPR001261

ArgE/DapE/ACY1/CPG2/YscS, conserved site
1. PS00758 (ARGE_DAPE_...)
  
  67 - 76
  
  PROSITE patterns
  PS00758 (ARGE_DAPE_CPG2_1)

no IPR

Unintegrated signatures

G3DSA:3.40.63...

2 - 276

GENE3D
G3DSA:3.40.630.10 (G3DSA:3.40.630.10)
PTHR43808 (FAMILY N...)

4 - 391

PANTHER
PTHR43808 (FAMILY NOT NAMED)
SSF53187 (Zn-depend...)

5 - 174

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

309 - 392

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

Residue annotation

putative metal bin...

72H

putative metal binding site
72H, 104D, 139E, 140E, 163E, 366H
CDD
cd05649 (M20_ArgE_DapE_like4)

104D

putative metal binding site
72H, 104D, 139E, 140E, 163E, 366H
CDD
cd05649 (M20_ArgE_DapE_like4)

139E

putative metal binding site
72H, 104D, 139E, 140E, 163E, 366H
CDD
cd05649 (M20_ArgE_DapE_like4)

140E

putative metal binding site
72H, 104D, 139E, 140E, 163E, 366H
CDD
cd05649 (M20_ArgE_DapE_like4)

163E

putative metal binding site
72H, 104D, 139E, 140E, 163E, 366H
CDD
cd05649 (M20_ArgE_DapE_like4)

366H

putative metal binding site
72H, 104D, 139E, 140E, 163E, 366H
CDD
cd05649 (M20_ArgE_DapE_like4)
putative dimer int...

178E

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

189H

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

190S

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

191A

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

192N

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

198N

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

200V

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

201Y

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

204M

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

205K

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

207I

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

208E

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

211K

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

225I

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

227E

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

228L

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

229T

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

230D

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

231I

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

232K

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

233S

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

234L

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

242V

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

243P

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

251D

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

253R

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

338N

putative dimer interface
178E, 189H, 190S, 191A, 192N, 198N, 200V, 201Y, 204M, 205K, 207I, 208E, 211K, 225I, 227E, 228L, 229T, 230D, 231I, 232K, 233S, 234L, 242V, 243P, 251D, 253R, 338N
CDD
cd05649 (M20_ArgE_DapE_like4)

GO term prediction

Biological Process

GO:0006508 proteolysis
GO:0008152 metabolic process

Molecular Function

GO:0008237 metallopeptidase activity
GO:0016787 hydrolase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_499

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component