1_1_36S_FusoPortal_Gene_748

Protein

1_1_36S_FusoPortal_Gene_748

Length

148 amino acids

Protein family membership

D-aminoacyl-tRNA deacylase DTD (IPR003732)

Homologous superfamilies

Homologous superfamily
1 - 145
D-Tyr tRNAtyr deacylase-like domain superfamily (IPR023509)

1 20 40 60 80 100 120 148

Domains and repeats

None predicted.

Detailed signature matches

IPR023509

D-Tyr tRNAtyr deacylase-like domain superfamily
1. SSF69500 (DTD-like)
  
  1 - 144
  
  SUPERFAMILY
  SSF69500 (DTD-like)
2. G3DSA:3.50.80.10
  
  1 - 145
  
  GENE3D
  G3DSA:3.50.80.10 (G3DSA:3.50.80.10)
IPR003732

D-aminoacyl-tRNA deacylase DTD
1. MF_00518 (Deacylase...)
  
  1 - 145
  
  HAMAP
  MF_00518 (Deacylase_Dtd)
2. TIGR00256
  
  1 - 145
  
  TIGRFAMs
  TIGR00256 (TIGR00256)
3. cd00563 (Dtyr_deacy...)
  
  1 - 145
  
  CDD
  cd00563 (Dtyr_deacylase)
4. PTHR10472 (D-TYROSY...)
  
  1 - 146
  
  PANTHER
  PTHR10472 (D-TYROSYL-TRNA TYR DEACYLASE)
5. PF02580 (Tyr_Deacylase)
  
  2 - 144
  
  Pfam
  PF02580 (Tyr_Deacylase)

no IPR

Unintegrated signatures

PTHR10472:SF5 (D-TY...)

1 - 146

PANTHER
PTHR10472:SF5 (D-TYROSYL-TRNA TYR DEACYLASE 1)

Residue annotation

putative active si...

7R

putative active site
7R, 77S, 78Q, 79F, 80T, 81L, 93F, 141F
CDD
cd00563 (Dtyr_deacylase)

77S

putative active site
7R, 77S, 78Q, 79F, 80T, 81L, 93F, 141F
CDD
cd00563 (Dtyr_deacylase)

78Q

putative active site
7R, 77S, 78Q, 79F, 80T, 81L, 93F, 141F
CDD
cd00563 (Dtyr_deacylase)

79F

putative active site
7R, 77S, 78Q, 79F, 80T, 81L, 93F, 141F
CDD
cd00563 (Dtyr_deacylase)

80T

putative active site
7R, 77S, 78Q, 79F, 80T, 81L, 93F, 141F
CDD
cd00563 (Dtyr_deacylase)

81L

putative active site
7R, 77S, 78Q, 79F, 80T, 81L, 93F, 141F
CDD
cd00563 (Dtyr_deacylase)

93F

putative active site
7R, 77S, 78Q, 79F, 80T, 81L, 93F, 141F
CDD
cd00563 (Dtyr_deacylase)

141F

putative active site
7R, 77S, 78Q, 79F, 80T, 81L, 93F, 141F
CDD
cd00563 (Dtyr_deacylase)
dimerization inter...

44W

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

47N

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

48K

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

49I

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

51D

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

52L

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

53R

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

54V

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

77S

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

78Q

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

80T

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

81L

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

83G

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

84N

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

85C

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

87K

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

88G

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

89R

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

90R

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

91P

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

93F

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

127A

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

128D

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

129M

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

130K

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

131V

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

132E

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

133L

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

134L

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

135N

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

136D

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

137G

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

138P

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

139V

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

140T

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

141F

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

142I

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

143I

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)

144E

dimerization interface
44W, 47N, 48K, 49I, 51D, 52L, 53R, 54V, 77S, 78Q, 80T, 81L, 83G, 84N, 85C, 87K, 88G, 89R, 90R, 91P, 93F, 127A, 128D, 129M, 130K, 131V, 132E, 133L, 134L, 135N, 136D, 137G, 138P, 139V, 140T, 141F, 142I, 143I, 144E
CDD
cd00563 (Dtyr_deacylase)
putative tRNAtyr b...

48K

putative tRNAtyr binding site
48K, 53R, 87K, 90R
CDD
cd00563 (Dtyr_deacylase)

53R

putative tRNAtyr binding site
48K, 53R, 87K, 90R
CDD
cd00563 (Dtyr_deacylase)

87K

putative tRNAtyr binding site
48K, 53R, 87K, 90R
CDD
cd00563 (Dtyr_deacylase)

90R

putative tRNAtyr binding site
48K, 53R, 87K, 90R
CDD
cd00563 (Dtyr_deacylase)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0002161 aminoacyl-tRNA editing activity
GO:0051499 D-aminoacyl-tRNA deacylase activity

Cellular Component

GO:0005737 cytoplasm

Filter view on

Entry type

Status

Per-residue features

1_1_36S_FusoPortal_Gene_748

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component