Filter view on

Protein

1_1_36S_FusoPortal_Gene_958

Length

381 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
1 - 120
Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily (IPR037069)
230 - 381
Acyl-CoA dehydrogenase-like, C-terminal (IPR036250)
Homologous superfamily
2 - 244
Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily (IPR009100)

1 50 100 150 200 250 300 350 381

Domains and repeats

Domain
7 - 118
Acyl-CoA dehydrogenase/oxidase, N-terminal (IPR013786)
122 - 219
Acyl-CoA oxidase/dehydrogenase, central domain (IPR006091)
231 - 378
Acyl-CoA dehydrogenase/oxidase C-terminal (IPR009075)

1 50 100 150 200 250 300 350 381

Detailed signature matches

IPR037069

Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily

G3DSA:1.10.54...

1 - 120

GENE3D
G3DSA:1.10.540.10 (G3DSA:1.10.540.10)

IPR009100

Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily

SSF56645 (Acyl-CoA ...)

2 - 244

SUPERFAMILY
SSF56645 (Acyl-CoA dehydrogenase NM domain-like)

IPR036250

Acyl-CoA dehydrogenase-like, C-terminal

SSF47203 (Acyl-CoA ...)

230 - 381

SUPERFAMILY
SSF47203 (Acyl-CoA dehydrogenase C-terminal domain-like)

IPR013786

Acyl-CoA dehydrogenase/oxidase, N-terminal

PF02771 (Acyl-CoA_dh_N)

7 - 118

Pfam
PF02771 (Acyl-CoA_dh_N)

IPR006091

Acyl-CoA oxidase/dehydrogenase, central domain

PF02770 (Acyl-CoA_dh_M)

122 - 219

Pfam
PF02770 (Acyl-CoA_dh_M)

IPR009075

Acyl-CoA dehydrogenase/oxidase C-terminal

PF00441 (Acyl-CoA_dh_1)

231 - 378

Pfam
PF00441 (Acyl-CoA_dh_1)

IPR006089

Acyl-CoA dehydrogenase, conserved site

PS00073 (ACYL_COA_DH_2)

338 - 357

PROSITE patterns
PS00073 (ACYL_COA_DH_2)
PS00072 (ACYL_COA_DH_1)

124 - 136

PROSITE patterns
PS00072 (ACYL_COA_DH_1)

no IPR

Unintegrated signatures

G3DSA:1.20.14...

220 - 381

GENE3D
G3DSA:1.20.140.10 (G3DSA:1.20.140.10)
G3DSA:2.40.11...

121 - 219

GENE3D
G3DSA:2.40.110.10 (G3DSA:2.40.110.10)
PIRSF016578 (PIGM)

6 - 380

PIRSF
PIRSF016578 (PIGM)
PTHR43884 (FAMILY N...)

2 - 381

PANTHER
PTHR43884 (FAMILY NOT NAMED)
PTHR43884:SF12 (SHO...)

2 - 381

PANTHER
PTHR43884:SF12 (SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL)
cd01158 (SCAD_SBCAD)

8 - 381

CDD
cd01158 (SCAD_SBCAD)

Residue annotation

FAD binding site c...

123F

FAD binding site
123F, 126T, 132T, 158F, 160T, 338Q, 342G, 365E
CDD
cd01158 (SCAD_SBCAD)

126T

FAD binding site
123F, 126T, 132T, 158F, 160T, 338Q, 342G, 365E
CDD
cd01158 (SCAD_SBCAD)

132T

FAD binding site
123F, 126T, 132T, 158F, 160T, 338Q, 342G, 365E
CDD
cd01158 (SCAD_SBCAD)

158F

FAD binding site
123F, 126T, 132T, 158F, 160T, 338Q, 342G, 365E
CDD
cd01158 (SCAD_SBCAD)

160T

FAD binding site
123F, 126T, 132T, 158F, 160T, 338Q, 342G, 365E
CDD
cd01158 (SCAD_SBCAD)

338Q

FAD binding site
123F, 126T, 132T, 158F, 160T, 338Q, 342G, 365E
CDD
cd01158 (SCAD_SBCAD)

342G

FAD binding site
123F, 126T, 132T, 158F, 160T, 338Q, 342G, 365E
CDD
cd01158 (SCAD_SBCAD)

365E

FAD binding site
123F, 126T, 132T, 158F, 160T, 338Q, 342G, 365E
CDD
cd01158 (SCAD_SBCAD)
homotetramer inter...

128P

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

133D

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

158F

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

201E

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

202K

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

203K

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

204L

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

205G

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

270R

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

273F

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

282N

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

286Q

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

287L

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

289N

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

292V

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

300L

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

323L

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

334T

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

338Q

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

343Y

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

345Y

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

347R

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

348E

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

352E

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

355M

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

356R

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

359K

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

360I

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

362E

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

369E

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

372R

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)

375I

homotetramer interface
128P, 133D, 158F, 201E, 202K, 203K, 204L, 205G, 270R, 273F, 282N, 286Q, 287L, 289N, 292V, 300L, 323L, 334T, 338Q, 343Y, 345Y, 347R, 348E, 352E, 355M, 356R, 359K, 360I, 362E, 369E, 372R, 375I
CDD
cd01158 (SCAD_SBCAD)
substrate binding ...

132T

substrate binding pocket
132T, 133D, 238M, 241L, 242D, 245R, 273F, 365E
CDD
cd01158 (SCAD_SBCAD)

133D

substrate binding pocket
132T, 133D, 238M, 241L, 242D, 245R, 273F, 365E
CDD
cd01158 (SCAD_SBCAD)

238M

substrate binding pocket
132T, 133D, 238M, 241L, 242D, 245R, 273F, 365E
CDD
cd01158 (SCAD_SBCAD)

241L

substrate binding pocket
132T, 133D, 238M, 241L, 242D, 245R, 273F, 365E
CDD
cd01158 (SCAD_SBCAD)

242D

substrate binding pocket
132T, 133D, 238M, 241L, 242D, 245R, 273F, 365E
CDD
cd01158 (SCAD_SBCAD)

245R

substrate binding pocket
132T, 133D, 238M, 241L, 242D, 245R, 273F, 365E
CDD
cd01158 (SCAD_SBCAD)

273F

substrate binding pocket
132T, 133D, 238M, 241L, 242D, 245R, 273F, 365E
CDD
cd01158 (SCAD_SBCAD)

365E

substrate binding pocket
132T, 133D, 238M, 241L, 242D, 245R, 273F, 365E
CDD
cd01158 (SCAD_SBCAD)
catalytic base cd0...

365E

catalytic base
365E
CDD
cd01158 (SCAD_SBCAD)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003995 acyl-CoA dehydrogenase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding

Cellular Component