23726_FusoPortal_Gene_1227

Protein

23726_FusoPortal_Gene_1227

Length

274 amino acids

Protein family membership

Glucosamine-6-phosphate isomerase (IPR004547)

Homologous superfamilies

Homologous superfamily
4 - 263
NagB/RpiA transferase-like (IPR037171)

1 50 100 150 200 274

Domains and repeats

Domain
15 - 226
Glucosamine/galactosamine-6-phosphate isomerase (IPR006148)

1 50 100 150 200 274

Detailed signature matches

IPR037171

NagB/RpiA transferase-like
1. SSF100950 (NagB/Rpi...)
  
  4 - 263
  
  SUPERFAMILY
  SSF100950 (NagB/RpiA/CoA transferase-like)
IPR004547

Glucosamine-6-phosphate isomerase
1. PTHR11280 (GLUCOSAM...)
  
  1 - 266
  
  PANTHER
  PTHR11280 (GLUCOSAMINE-6-PHOSPHATE ISOMERASE)
2. TIGR00502
  
  2 - 258
  
  TIGRFAMs
  TIGR00502 (TIGR00502)
3. cd01399 (GlcN6P_dea...)
  
  11 - 246
  
  CDD
  cd01399 (GlcN6P_deaminase)
4. MF_01241 (GlcN6P_de...)
  
  1 - 246
  
  HAMAP
  MF_01241 (GlcN6P_deamin)
IPR006148

Glucosamine/galactosamine-6-phosphate isomerase
1. PF01182 (Glucosamin...)
  
  15 - 226
  
  Pfam
  PF01182 (Glucosamine_iso)
IPR018321

Glucosamine-6-phosphate isomerase, conserved site
1. PS01161 (GLC_GALNAC...)
  
  124 - 142
  
  PROSITE patterns
  PS01161 (GLC_GALNAC_ISOMERASE)

no IPR

Unintegrated signatures

Coil

103 - 123

COILS
Coil (Coil)
G3DSA:3.40.50...

1 - 265

GENE3D
G3DSA:3.40.50.1360 (G3DSA:3.40.50.1360)
PTHR11280:SF17 (GLU...)

1 - 266

PANTHER
PTHR11280:SF17 (GLUCOSAMINE-6-PHOSPHATE ISOMERASE)

Residue annotation

active site cd01399

40T

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

41G

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

42S

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

43T

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

70M

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

71D

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

136G

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

137V

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

142H

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

144A

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

171R

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)

207K

active site
40T, 41G, 42S, 43T, 70M, 71D, 136G, 137V, 142H, 144A, 171R, 207K
CDD
cd01399 (GlcN6P_deaminase)
trimer interface c...

149G

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

151S

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

152F

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

160Q

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

215I

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

216E

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

217E

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

218G

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

219I

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

220N

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

221H

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

229Q

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

230L

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)

231H

trimer interface
149G, 151S, 152F, 160Q, 215I, 216E, 217E, 218G, 219I, 220N, 221H, 229Q, 230L, 231H
CDD
cd01399 (GlcN6P_deaminase)
allosteric site cd...

150S

allosteric site
150S, 151S, 157R, 158E, 159K, 160Q
CDD
cd01399 (GlcN6P_deaminase)

151S

allosteric site
150S, 151S, 157R, 158E, 159K, 160Q
CDD
cd01399 (GlcN6P_deaminase)

157R

allosteric site
150S, 151S, 157R, 158E, 159K, 160Q
CDD
cd01399 (GlcN6P_deaminase)

158E

allosteric site
150S, 151S, 157R, 158E, 159K, 160Q
CDD
cd01399 (GlcN6P_deaminase)

159K

allosteric site
150S, 151S, 157R, 158E, 159K, 160Q
CDD
cd01399 (GlcN6P_deaminase)

160Q

allosteric site
150S, 151S, 157R, 158E, 159K, 160Q
CDD
cd01399 (GlcN6P_deaminase)
active site lid cd...

162T

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

165T

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

166I

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

167I

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

168V

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

169N

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

170S

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

171R

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

172F

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

173F

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

174N

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

175N

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

179K

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

180V

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)

181P

active site lid
162T, 165T, 166I, 167I, 168V, 169N, 170S, 171R, 172F, 173F, 174N, 175N, 179K, 180V, 181P
CDD
cd01399 (GlcN6P_deaminase)
hexamer (dimer of ...

167I

hexamer (dimer of trimers) interface
167I, 205N, 209R, 240E, 243C, 244A, 245E, 246L
CDD
cd01399 (GlcN6P_deaminase)

205N

hexamer (dimer of trimers) interface
167I, 205N, 209R, 240E, 243C, 244A, 245E, 246L
CDD
cd01399 (GlcN6P_deaminase)

209R

hexamer (dimer of trimers) interface
167I, 205N, 209R, 240E, 243C, 244A, 245E, 246L
CDD
cd01399 (GlcN6P_deaminase)

240E

hexamer (dimer of trimers) interface
167I, 205N, 209R, 240E, 243C, 244A, 245E, 246L
CDD
cd01399 (GlcN6P_deaminase)

243C

hexamer (dimer of trimers) interface
167I, 205N, 209R, 240E, 243C, 244A, 245E, 246L
CDD
cd01399 (GlcN6P_deaminase)

244A

hexamer (dimer of trimers) interface
167I, 205N, 209R, 240E, 243C, 244A, 245E, 246L
CDD
cd01399 (GlcN6P_deaminase)

245E

hexamer (dimer of trimers) interface
167I, 205N, 209R, 240E, 243C, 244A, 245E, 246L
CDD
cd01399 (GlcN6P_deaminase)

246L

hexamer (dimer of trimers) interface
167I, 205N, 209R, 240E, 243C, 244A, 245E, 246L
CDD
cd01399 (GlcN6P_deaminase)

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0006044 N-acetylglucosamine metabolic process

Molecular Function

GO:0004342 glucosamine-6-phosphate deaminase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

23726_FusoPortal_Gene_1227

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component