23726_FusoPortal_Gene_1389

Protein

23726_FusoPortal_Gene_1389

Length

1,245 amino acids

Protein family membership

Phosphoribosylformylglycinamidine synthase, FGAM (IPR010141)

Homologous superfamilies

Homologous superfamily
192 - 446
PurM-like, N-terminal domain superfamily (IPR036921)
617 - 815
PurM-like, N-terminal domain superfamily (IPR036921)
Homologous superfamily
435 - 608
PurM-like, C-terminal domain superfamily (IPR036676)
816 - 956
PurM-like, C-terminal domain superfamily (IPR036676)
979 - 1,245
Class I glutamine amidotransferase-like (IPR029062)

1 200 400 600 800 1000 1245

Domains and repeats

Domain
441 - 592
PurM-like, C-terminal domain (IPR010918)

1 200 400 600 800 1000 1245

Detailed signature matches

IPR036921

PurM-like, N-terminal domain superfamily
1. SSF55326 (PurM N-te...)
  
  297 - 446
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
  
  192 - 228
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
  
  629 - 815
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
2. G3DSA:3.30.13...
  
  617 - 811
  
  GENE3D
  G3DSA:3.30.1330.10 (G3DSA:3.30.1330.10)
  
  202 - 434
  
  GENE3D
  G3DSA:3.30.1330.10 (G3DSA:3.30.1330.10)
IPR036676

PurM-like, C-terminal domain superfamily
1. SSF56042 (PurM C-te...)
  
  441 - 607
  
  SUPERFAMILY
  SSF56042 (PurM C-terminal domain-like)
  
  816 - 956
  
  SUPERFAMILY
  SSF56042 (PurM C-terminal domain-like)
2. G3DSA:3.90.65...
  
  824 - 951
  
  GENE3D
  G3DSA:3.90.650.10 (G3DSA:3.90.650.10)
  
  435 - 608
  
  GENE3D
  G3DSA:3.90.650.10 (G3DSA:3.90.650.10)
IPR029062

Class I glutamine amidotransferase-like
1. G3DSA:3.40.50...
  
  981 - 1,245
  
  GENE3D
  G3DSA:3.40.50.880 (G3DSA:3.40.50.880)
2. SSF52317 (Class I g...)
  
  979 - 1,244
  
  SUPERFAMILY
  SSF52317 (Class I glutamine amidotransferase-like)
IPR010141

Phosphoribosylformylglycinamidine synthase, FGAM
1. TIGR01857
  
  5 - 1,244
  
  TIGRFAMs
  TIGR01857 (TIGR01857)
IPR010918

PurM-like, C-terminal domain
1. PF02769 (AIRS_C)
  
  441 - 592
  
  Pfam
  PF02769 (AIRS_C)

no IPR

Unintegrated signatures

PF13507 (GATase_5)

982 - 1,244

Pfam
PF13507 (GATase_5)
PTHR10099 (PHOSPHOR...)

2 - 1,244

PANTHER
PTHR10099 (PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE)
PTHR10099:SF1 (PHOS...)

2 - 1,244

PANTHER
PTHR10099:SF1 (PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE)
cd01740 (GATase1_FG...)

985 - 1,241

CDD
cd01740 (GATase1_FGAR_AT)
cd02203 (PurL_repeat1)

211 - 600

CDD
cd02203 (PurL_repeat1)
cd02204 (PurL_repeat2)

683 - 909

CDD
cd02204 (PurL_repeat2)

Residue annotation

dimerization inter...

318L

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

319L

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

320M

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

321F

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

323N

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

348D

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

358Q

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

361R

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

364G

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

408S

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

419R

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

420M

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)

424A

dimerization interface
318L, 319L, 320M, 321F, 323N, 348D, 358Q, 361R, 364G, 408S, 419R, 420M, 424A
CDD
cd02203 (PurL_repeat1)
ATP binding site c...

344G

ATP binding site
344G, 348D, 406L, 407V, 408S
CDD
cd02203 (PurL_repeat1)

348D

ATP binding site
344G, 348D, 406L, 407V, 408S
CDD
cd02203 (PurL_repeat1)

406L

ATP binding site
344G, 348D, 406L, 407V, 408S
CDD
cd02203 (PurL_repeat1)

407V

ATP binding site
344G, 348D, 406L, 407V, 408S
CDD
cd02203 (PurL_repeat1)

408S

ATP binding site
344G, 348D, 406L, 407V, 408S
CDD
cd02203 (PurL_repeat1)
dimerization inter...

699A

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

700S

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

701A

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

702I

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

704W

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

729K

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

742L

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

745Q

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

748F

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

783K

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

797P

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

798T

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)

802F

dimerization interface
699A, 700S, 701A, 702I, 704W, 729K, 742L, 745Q, 748F, 783K, 797P, 798T, 802F
CDD
cd02204 (PurL_repeat2)
ATP binding site c...

725E

ATP binding site
725E, 729K, 781G, 782G, 783K
CDD
cd02204 (PurL_repeat2)

729K

ATP binding site
725E, 729K, 781G, 782G, 783K
CDD
cd02204 (PurL_repeat2)

781G

ATP binding site
725E, 729K, 781G, 782G, 783K
CDD
cd02204 (PurL_repeat2)

782G

ATP binding site
725E, 729K, 781G, 782G, 783K
CDD
cd02204 (PurL_repeat2)

783K

ATP binding site
725E, 729K, 781G, 782G, 783K
CDD
cd02204 (PurL_repeat2)
putative active si...

1,045G

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,046F

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,050D

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,086C

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,090Q

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,152S

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,153H

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,214M

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,216H

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,217S

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,218E

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)

1,219R

putative active site
1,045G, 1,046F, 1,050D, 1,086C, 1,090Q, 1,152S, 1,153H, 1,214M, 1,216H, 1,217S, 1,218E, 1,219R
CDD
cd01740 (GATase1_FGAR_AT)
catalytic triad cd...

1,086C

catalytic triad
1,086C, 1,216H, 1,218E
CDD
cd01740 (GATase1_FGAR_AT)

1,216H

catalytic triad
1,086C, 1,216H, 1,218E
CDD
cd01740 (GATase1_FGAR_AT)

1,218E

catalytic triad
1,086C, 1,216H, 1,218E
CDD
cd01740 (GATase1_FGAR_AT)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

23726_FusoPortal_Gene_1389

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component