23726_FusoPortal_Gene_1470

Protein

23726_FusoPortal_Gene_1470

Length

354 amino acids

Protein family membership

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic (IPR017846)

Homologous superfamilies

Homologous superfamily
8 - 74
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal (IPR023195)
Homologous superfamily
9 - 348
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily (IPR036087)

1 50 100 150 200 250 300 354

Domains and repeats

Domain
14 - 348
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like (IPR003200)

1 50 100 150 200 250 300 354

Detailed signature matches

IPR023195

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal
1. G3DSA:1.10.16...
  
  8 - 74
  
  GENE3D
  G3DSA:1.10.1610.10 (G3DSA:1.10.1610.10)
IPR036087

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily
1. SSF52733 (Nicotinat...)
  
  9 - 348
  
  SUPERFAMILY
  SSF52733 (Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT))
IPR017846

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic
1. MF_00230 (CobT)
  
  16 - 352
  
  HAMAP
  MF_00230 (CobT)
2. TIGR03160
  
  18 - 347
  
  TIGRFAMs
  TIGR03160 (TIGR03160)
IPR003200

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like
1. cd02439 (DMB-PRT_CobT)
  
  34 - 348
  
  CDD
  cd02439 (DMB-PRT_CobT)
2. PF02277 (DBI_PRT)
  
  14 - 347
  
  Pfam
  PF02277 (DBI_PRT)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

75 - 333

GENE3D
G3DSA:3.40.50.10210 (G3DSA:3.40.50.10210)
PTHR43463 (FAMILY N...)

2 - 347

PANTHER
PTHR43463 (FAMILY NOT NAMED)
PTHR43463:SF1 (NICO...)

2 - 347

PANTHER
PTHR43463:SF1 (NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE)

Residue annotation

putative dimer int...

34K

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

35P

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

36K

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

37D

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

38S

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

39L

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

40G

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

41V

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

42L

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

81S

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

86Y

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

89I

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

90V

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

98I

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

99A

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

100C

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

103I

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

104F

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

106K

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

296E

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

310K

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

312F

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

313L

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

314N

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

315M

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

316N

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

317M

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

319L

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

327L

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

330P

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

334C

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

337E

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

338M

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

342M

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

343K

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)

348V

putative dimer interface
34K, 35P, 36K, 37D, 38S, 39L, 40G, 41V, 42L, 81S, 86Y, 89I, 90V, 98I, 99A, 100C, 103I, 104F, 106K, 296E, 310K, 312F, 313L, 314N, 315M, 316N, 317M, 319L, 327L, 330P, 334C, 337E, 338M, 342M, 343K, 348V
CDD
cd02439 (DMB-PRT_CobT)
active site pocket...

35P

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

36K

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

80S

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

86Y

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

90V

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

178E

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

179M

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

180G

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

181I

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

182A

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

183N

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

184T

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

268G

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

269F

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

270I

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

295S

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

319L

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

320G

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

321E

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)

344S

active site pocket
35P, 36K, 80S, 86Y, 90V, 178E, 179M, 180G, 181I, 182A, 183N, 184T, 268G, 269F, 270I, 295S, 319L, 320G, 321E, 344S
CDD
cd02439 (DMB-PRT_CobT)
putative cataytic ...

321E

putative cataytic base
321E
CDD
cd02439 (DMB-PRT_CobT)

GO term prediction

Biological Process

GO:0009163 nucleoside biosynthetic process
GO:0009236 cobalamin biosynthetic process

Molecular Function

GO:0008939 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

23726_FusoPortal_Gene_1470

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component