23726_FusoPortal_Gene_1481

Protein

23726_FusoPortal_Gene_1481

Length

238 amino acids

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)

Homologous superfamilies

Homologous superfamily
1 - 212
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 238

Domains and repeats

None predicted.

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  1 - 212
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR002347

Short-chain dehydrogenase/reductase SDR
1. PR00080 (SDRFAMILY)
  
  124 - 132
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  72 - 83
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  144 - 163
  
  PRINTS
  PR00080 (SDRFAMILY)
2. PR00081 (GDHRDH)
  
  118 - 134
  
  PRINTS
  PR00081 (GDHRDH)
  
  72 - 83
  
  PRINTS
  PR00081 (GDHRDH)
  
  3 - 20
  
  PRINTS
  PR00081 (GDHRDH)
  
  165 - 182
  
  PRINTS
  PR00081 (GDHRDH)
  
  144 - 163
  
  PRINTS
  PR00081 (GDHRDH)
3. PF00106 (adh_short)
  
  2 - 183
  
  Pfam
  PF00106 (adh_short)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

1 - 223

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PTHR42879 (FAMILY N...)

2 - 229

PANTHER
PTHR42879 (FAMILY NOT NAMED)
PTHR42879:SF2 (SUBF...)

2 - 229

PANTHER
PTHR42879:SF2 (SUBFAMILY NOT NAMED)
cd05233 (SDR_c)

4 - 211

CDD
cd05233 (SDR_c)

Residue annotation

NAD(P) binding sit...

8G

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

10T

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

11S

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

12G

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

13I

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

32G

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

33R

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

34N

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

54C

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

55D

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

56L

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

80S

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

81A

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

82G

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

103V

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

129I

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

130S

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

131S

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

144Y

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

148K

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

174P

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

175D

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

176M

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

177T

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

179T

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)

180N

NAD(P) binding site
8G, 10T, 11S, 12G, 13I, 32G, 33R, 34N, 54C, 55D, 56L, 80S, 81A, 82G, 103V, 129I, 130S, 131S, 144Y, 148K, 174P, 175D, 176M, 177T, 179T, 180N
CDD
cd05233 (SDR_c)
active site cd05233

104N

active site
104N, 131S, 144Y, 148K
CDD
cd05233 (SDR_c)

131S

active site
104N, 131S, 144Y, 148K
CDD
cd05233 (SDR_c)

144Y

active site
104N, 131S, 144Y, 148K
CDD
cd05233 (SDR_c)

148K

active site
104N, 131S, 144Y, 148K
CDD
cd05233 (SDR_c)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

23726_FusoPortal_Gene_1481

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component