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Protein

23726_FusoPortal_Gene_1578

Length

340 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
1 - 338
Pyridoxal phosphate-dependent transferase (IPR015424)
Homologous superfamily
1 - 245
Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (IPR015421)
246 - 340
Pyridoxal phosphate-dependent transferase, subdomain 2 (IPR015422)

1 50 100 150 200 250 300 340

Domains and repeats

Domain
11 - 291
Aromatic amino acid beta-eliminating lyase/threonine aldolase (IPR001597)

1 50 100 150 200 250 300 340

Detailed signature matches

IPR015421

Pyridoxal phosphate-dependent transferase, major region, subdomain 1

G3DSA:3.40.64...

1 - 245

GENE3D
G3DSA:3.40.640.10 (G3DSA:3.40.640.10)

IPR015424

Pyridoxal phosphate-dependent transferase

SSF53383 (PLP-depen...)

1 - 338

SUPERFAMILY
SSF53383 (PLP-dependent transferases)

IPR015422

Pyridoxal phosphate-dependent transferase, subdomain 2

G3DSA:3.90.11...

246 - 340

GENE3D
G3DSA:3.90.1150.10 (G3DSA:3.90.1150.10)

IPR001597

Aromatic amino acid beta-eliminating lyase/threonine aldolase

PF01212 (Beta_elim_...)

11 - 291

Pfam
PF01212 (Beta_elim_lyase)

no IPR

Unintegrated signatures

PTHR43703 (FAMILY N...)

1 - 339

PANTHER
PTHR43703 (FAMILY NOT NAMED)
cd06502 (TA_like)

4 - 340

CDD
cd06502 (TA_like)

Residue annotation

tetramer interface...

5K

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

8Y

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

9S

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

10E

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

11G

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

17L

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

20L

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

21I

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

22K

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

59V

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

62T

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

63Q

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

70S

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

88S

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

89I

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

90H

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

91E

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

92T

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

93G

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

94A

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

95I

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

101K

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

102I

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

103I

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

201T

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

202K

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

208G

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

223N

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

224F

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

227K

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

228Q

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

238L

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

239L

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)

309F

tetramer interface
5K, 8Y, 9S, 10E, 11G, 17L, 20L, 21I, 22K, 59V, 62T, 63Q, 70S, 88S, 89I, 90H, 91E, 92T, 93G, 94A, 95I, 101K, 102I, 103I, 201T, 202K, 208G, 223N, 224F, 227K, 228Q, 238L, 239L, 309F
CDD
cd06502 (TA_like)
pyridoxal 5'-phosp...

61G

pyridoxal 5'-phosphate binding site
61G, 62T, 65N, 138S, 169D, 172R, 199G, 202K
CDD
cd06502 (TA_like)

62T

pyridoxal 5'-phosphate binding site
61G, 62T, 65N, 138S, 169D, 172R, 199G, 202K
CDD
cd06502 (TA_like)

65N

pyridoxal 5'-phosphate binding site
61G, 62T, 65N, 138S, 169D, 172R, 199G, 202K
CDD
cd06502 (TA_like)

138S

pyridoxal 5'-phosphate binding site
61G, 62T, 65N, 138S, 169D, 172R, 199G, 202K
CDD
cd06502 (TA_like)

169D

pyridoxal 5'-phosphate binding site
61G, 62T, 65N, 138S, 169D, 172R, 199G, 202K
CDD
cd06502 (TA_like)

172R

pyridoxal 5'-phosphate binding site
61G, 62T, 65N, 138S, 169D, 172R, 199G, 202K
CDD
cd06502 (TA_like)

199G

pyridoxal 5'-phosphate binding site
61G, 62T, 65N, 138S, 169D, 172R, 199G, 202K
CDD
cd06502 (TA_like)

202K

pyridoxal 5'-phosphate binding site
61G, 62T, 65N, 138S, 169D, 172R, 199G, 202K
CDD
cd06502 (TA_like)
catalytic residue ...

202K

catalytic residue
202K
CDD
cd06502 (TA_like)

GO term prediction

Biological Process

GO:0006520 cellular amino acid metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0016829 lyase activity

Cellular Component