23726_FusoPortal_Gene_1584

Protein

23726_FusoPortal_Gene_1584

Length

245 amino acids

Protein family membership

Acylneuraminate cytidylyltransferase (IPR003329)
- 3-deoxy-D-manno-octulosonate cytidylyltransferase (IPR004528)

Homologous superfamilies

Homologous superfamily
1 - 243
Nucleotide-diphospho-sugar transferases (IPR029044)

1 50 100 150 200 245

Domains and repeats

None predicted.

Detailed signature matches

IPR029044

Nucleotide-diphospho-sugar transferases
1. G3DSA:3.90.55...
  
  1 - 243
  
  GENE3D
  G3DSA:3.90.550.10 (G3DSA:3.90.550.10)
2. SSF53448 (Nucleotid...)
  
  1 - 242
  
  SUPERFAMILY
  SSF53448 (Nucleotide-diphospho-sugar transferases)
IPR003329

Acylneuraminate cytidylyltransferase
1. PF02348 (CTP_transf_3)
  
  5 - 213
  
  Pfam
  PF02348 (CTP_transf_3)
IPR004528

3-deoxy-D-manno-octulosonate cytidylyltransferase
1. TIGR00466
  
  1 - 232
  
  TIGRFAMs
  TIGR00466 (TIGR00466)
2. MF_00057 (KdsB)
  
  1 - 239
  
  HAMAP
  MF_00057 (KdsB)
3. cd02517 (CMP-KDO-Sy...)
  
  2 - 237
  
  CDD
  cd02517 (CMP-KDO-Synthetase)

no IPR

Unintegrated signatures

PTHR42866 (FAMILY N...)

2 - 241

PANTHER
PTHR42866 (FAMILY NOT NAMED)
PTHR42866:SF2 (3-DE...)

2 - 241

PANTHER
PTHR42866:SF2 (3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL)

Residue annotation

Ligand binding sit...

8P

Ligand binding site
8P, 9A, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

9A

Ligand binding site
8P, 9A, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

10R

Ligand binding site
8P, 9A, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

48A

Ligand binding site
8P, 9A, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

75G

Ligand binding site
8P, 9A, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

96Q

Ligand binding site
8P, 9A, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

98D

Ligand binding site
8P, 9A, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)
oligomer interface...

121K

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

138P

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

144V

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

145C

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

146D

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

152I

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

153Y

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

155S

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

156R

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

157S

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

158V

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

159I

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

160P

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

161Y

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

169S

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

194P

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

195L

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

198I

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

199E

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

200S

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

207L

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

208E

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

209N

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

210G

oligomer interface
121K, 138P, 144V, 145C, 146D, 152I, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169S, 194P, 195L, 198I, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0008690 3-deoxy-manno-octulosonate cytidylyltransferase activity

Cellular Component

GO:0005737 cytoplasm

Filter view on

Entry type

Status

Per-residue features

23726_FusoPortal_Gene_1584

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component