23726_FusoPortal_Gene_2007

Protein

23726_FusoPortal_Gene_2007

Length

1,133 amino acids

Protein family membership

DNA polymerase III, alpha subunit (IPR004805)

Homologous superfamilies

Homologous superfamily
5 - 248
Polymerase/histidinol phosphatase-like (IPR016195)

1 200 400 600 800 1000 1133

Domains and repeats

Domain
7 - 171
PHP domain (IPR004013)
292 - 717
Bacterial DNA polymerase III, alpha subunit (IPR011708)
791 - 878
DNA polymerase, helix-hairpin-helix motif (IPR029460)

1 200 400 600 800 1000 1133

Detailed signature matches

IPR016195

Polymerase/histidinol phosphatase-like
1. SSF89550 (PHP domai...)
  
  5 - 248
  
  SUPERFAMILY
  SSF89550 (PHP domain-like)
IPR004805

DNA polymerase III, alpha subunit
1. TIGR00594
  
  5 - 999
  
  TIGRFAMs
  TIGR00594 (TIGR00594)
2. PTHR32294 (FAMILY N...)
  
  1 - 1,130
  
  PANTHER
  PTHR32294 (FAMILY NOT NAMED)
IPR004013

PHP domain
1. PF02811 (PHP)
  
  7 - 171
  
  Pfam
  PF02811 (PHP)
IPR011708

Bacterial DNA polymerase III, alpha subunit
1. PF07733 (DNA_pol3_a...)
  
  292 - 717
  
  Pfam
  PF07733 (DNA_pol3_alpha)
IPR029460

DNA polymerase, helix-hairpin-helix motif
1. PF14579 (HHH_6)
  
  791 - 878
  
  Pfam
  PF14579 (HHH_6)

no IPR

Unintegrated signatures

G3DSA:1.10.15...

795 - 875

GENE3D
G3DSA:1.10.150.280 (G3DSA:1.10.150.280)
G3DSA:2.40.50...

950 - 1,051

GENE3D
G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
G3DSA:3.20.20...

4 - 258

GENE3D
G3DSA:3.20.20.140 (G3DSA:3.20.20.140)
PTHR32294:SF0 (DNA ...)

1 - 1,130

PANTHER
PTHR32294:SF0 (DNA POLYMERASE III SUBUNIT ALPHA)
cd04485 (DnaE_OBF)

975 - 1,057

CDD
cd04485 (DnaE_OBF)

Residue annotation

generic binding su...

977I

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

978I

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

979N

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

993M

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

994F

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

995N

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

996L

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

998C

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,004S

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,005C

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,006I

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,008F

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,023K

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,030K

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,031I

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,032Q

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,043K

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,044L

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)

1,045L

generic binding surface I
977I, 978I, 979N, 993M, 994F, 995N, 996L, 998C, 1,004S, 1,005C, 1,006I, 1,008F, 1,023K, 1,030K, 1,031I, 1,032Q, 1,043K, 1,044L, 1,045L
CDD
cd04485 (DnaE_OBF)
generic binding su...

1,024T

generic binding surface II
1,024T, 1,026Y, 1,028E, 1,050V
CDD
cd04485 (DnaE_OBF)

1,026Y

generic binding surface II
1,024T, 1,026Y, 1,028E, 1,050V
CDD
cd04485 (DnaE_OBF)

1,028E

generic binding surface II
1,024T, 1,026Y, 1,028E, 1,050V
CDD
cd04485 (DnaE_OBF)

1,050V

generic binding surface II
1,024T, 1,026Y, 1,028E, 1,050V
CDD
cd04485 (DnaE_OBF)

GO term prediction

Biological Process

GO:0006260 DNA replication

Molecular Function

GO:0003824 catalytic activity
GO:0008408 3'-5' exonuclease activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

23726_FusoPortal_Gene_2007

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component