23726_FusoPortal_Gene_2

Protein

23726_FusoPortal_Gene_2

Length

391 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Homologous superfamilies

Homologous superfamily
20 - 390
MFS transporter superfamily (IPR036259)

1 50 100 150 200 250 300 350 391

Domains and repeats

Domain
1 - 389
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 391

Detailed signature matches

IPR036259

MFS transporter superfamily
1. SSF103473 (MFS gene...)
  
  20 - 390
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  26 - 342
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  1 - 389
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  21 - 329
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

199 - 391

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

3 - 195

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
PTHR23530 (FAMILY N...)

6 - 390

PANTHER
PTHR23530 (FAMILY NOT NAMED)

Residue annotation

putative substrate...

22Y

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

23D

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

24S

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

26I

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

27T

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

44W

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

47V

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

48L

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

51Q

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

55D

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

56Y

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

58T

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

59G

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

105E

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

106S

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

109S

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

110G

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

113F

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

114P

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

117V

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

137N

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

138G

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

141Q

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

142Y

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

148G

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

222Y

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

225Y

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

226S

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

229L

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

230F

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

233Q

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

247T

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

251S

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

255S

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

306G

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

309N

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

310G

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

313A

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

317M

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

318S

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

321H

putative substrate translocation pore
22Y, 23D, 24S, 26I, 27T, 44W, 47V, 48L, 51Q, 55D, 56Y, 58T, 59G, 105E, 106S, 109S, 110G, 113F, 114P, 117V, 137N, 138G, 141Q, 142Y, 148G, 222Y, 225Y, 226S, 229L, 230F, 233Q, 247T, 251S, 255S, 306G, 309N, 310G, 313A, 317M, 318S, 321H
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features

23726_FusoPortal_Gene_2

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component