23726_FusoPortal_Gene_717

Protein

23726_FusoPortal_Gene_717

Length

497 amino acids

Protein family membership

Carbohydrate kinase, FGGY (IPR000577)
- Glycerol kinase (IPR005999)

Homologous superfamilies

None predicted.

Domains and repeats

Domain
3 - 251
Carbohydrate kinase, FGGY, N-terminal (IPR018484)
261 - 449
Carbohydrate kinase, FGGY, C-terminal (IPR018485)

1 50 100 150 200 250 300 350 400 450 497

Detailed signature matches

IPR000577

Carbohydrate kinase, FGGY
1. PIRSF000538 (GlpK)
  
  1 - 497
  
  PIRSF
  PIRSF000538 (GlpK)
IPR005999

Glycerol kinase
1. TIGR01311
  
  2 - 495
  
  TIGRFAMs
  TIGR01311 (TIGR01311)
2. MF_00186 (Glycerol_kin)
  
  1 - 496
  
  HAMAP
  MF_00186 (Glycerol_kin)
IPR018484

Carbohydrate kinase, FGGY, N-terminal
1. PF00370 (FGGY_N)
  
  3 - 251
  
  Pfam
  PF00370 (FGGY_N)
IPR018485

Carbohydrate kinase, FGGY, C-terminal
1. PF02782 (FGGY_C)
  
  261 - 449
  
  Pfam
  PF02782 (FGGY_C)
IPR018483

Carbohydrate kinase, FGGY, conserved site
1. PS00445 (FGGY_KINAS...)
  
  361 - 381
  
  PROSITE patterns
  PS00445 (FGGY_KINASES_2)
2. PS00933 (FGGY_KINAS...)
  
  134 - 146
  
  PROSITE patterns
  PS00933 (FGGY_KINASES_1)

no IPR

Unintegrated signatures

G3DSA:3.30.42...

248 - 497

GENE3D
G3DSA:3.30.420.40 (G3DSA:3.30.420.40)

1 - 247

GENE3D
G3DSA:3.30.420.40 (G3DSA:3.30.420.40)
PTHR10196 (SUGAR KI...)

1 - 496

PANTHER
PTHR10196 (SUGAR KINASE)
PTHR10196:SF69 (GH1...)

1 - 496

PANTHER
PTHR10196:SF69 (GH12641P)
SSF53067 (Actin-lik...)

2 - 254

SUPERFAMILY
SSF53067 (Actin-like ATPase domain)

254 - 495

SUPERFAMILY
SSF53067 (Actin-like ATPase domain)
cd07786 (FGGY_EcGK_...)

3 - 490

CDD
cd07786 (FGGY_EcGK_like)

Residue annotation

N- and C-terminal ...

3Y

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

4I

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

6A

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

8D

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

11T

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

12T

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

15R

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

17I

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

19F

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

20D

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

23Q

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

25I

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

41G

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

73I

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

74A

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

75L

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

76G

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

77I

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

78T

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

79N

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

80Q

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

81R

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

101W

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

102Q

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

104R

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

107A

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

111D

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

124K

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

127T

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

128G

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

129L

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

130L

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

132D

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

134Y

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

135F

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

182Y

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

183T

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

186S

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

187R

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

193I

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

194K

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

196L

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

218D

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

219S

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

220S

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

221G

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

239A

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

240G

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

246Q

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

247S

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

266T

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

269F

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

278F

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

280K

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

286I

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

287T

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

288T

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

289I

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

290A

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

291I

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

292G

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

297V

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

299Y

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

302E

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

304S

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

306F

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

307V

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

313Q

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

348V

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

355W

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

357M

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

358Y

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

360R

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

436E

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

438T

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

439A

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

440L

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

442A

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

443A

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

445L

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

446A

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

447G

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

448L

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

449A

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

450V

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

452F

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)

453W

N- and C-terminal domain interface
3Y, 4I, 6A, 8D, 11T, 12T, 15R, 17I, 19F, 20D, 23Q, 25I, 41G, 73I, 74A, 75L, 76G, 77I, 78T, 79N, 80Q, 81R, 101W, 102Q, 104R, 107A, 111D, 124K, 127T, 128G, 129L, 130L, 132D, 134Y, 135F, 182Y, 183T, 186S, 187R, 193I, 194K, 196L, 218D, 219S, 220S, 221G, 239A, 240G, 246Q, 247S, 266T, 269F, 278F, 280K, 286I, 287T, 288T, 289I, 290A, 291I, 292G, 297V, 299Y, 302E, 304S, 306F, 307V, 313Q, 348V, 355W, 357M, 358Y, 360R, 436E, 438T, 439A, 440L, 442A, 443A, 445L, 446A, 447G, 448L, 449A, 450V, 452F, 453W
CDD
cd07786 (FGGY_EcGK_like)
catalytic site cd0...

8D

catalytic site
8D, 11T, 244D
CDD
cd07786 (FGGY_EcGK_like)

11T

catalytic site
8D, 11T, 244D
CDD
cd07786 (FGGY_EcGK_like)

244D

catalytic site
8D, 11T, 244D
CDD
cd07786 (FGGY_EcGK_like)
metal binding site...

8D

metal binding site
8D, 244D
CDD
cd07786 (FGGY_EcGK_like)

244D

metal binding site
8D, 244D
CDD
cd07786 (FGGY_EcGK_like)
MgATP binding site...

8D

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

10G

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

11T

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

12T

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

15R

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

264Y

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

265G

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

266T

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

309G

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

310A

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

312V

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

313Q

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

325S

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

326K

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

328T

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

409G

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

410G

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

411A

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

414N

MgATP binding site
8D, 10G, 11T, 12T, 15R, 264Y, 265G, 266T, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)
active site cd07786

8D

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

10G

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

11T

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

12T

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

15R

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

80Q

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

81R

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

82E

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

101W

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

134Y

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

244D

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

245Q

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

264Y

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

265G

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

266T

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

269F

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

309G

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

310A

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

312V

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

313Q

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

325S

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

326K

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

328T

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

409G

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

410G

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

411A

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)

414N

active site
8D, 10G, 11T, 12T, 15R, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 264Y, 265G, 266T, 269F, 309G, 310A, 312V, 313Q, 325S, 326K, 328T, 409G, 410G, 411A, 414N
CDD
cd07786 (FGGY_EcGK_like)
glycerol binding s...

11T

glycerol binding site
11T, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 269F
CDD
cd07786 (FGGY_EcGK_like)

80Q

glycerol binding site
11T, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 269F
CDD
cd07786 (FGGY_EcGK_like)

81R

glycerol binding site
11T, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 269F
CDD
cd07786 (FGGY_EcGK_like)

82E

glycerol binding site
11T, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 269F
CDD
cd07786 (FGGY_EcGK_like)

101W

glycerol binding site
11T, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 269F
CDD
cd07786 (FGGY_EcGK_like)

134Y

glycerol binding site
11T, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 269F
CDD
cd07786 (FGGY_EcGK_like)

244D

glycerol binding site
11T, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 269F
CDD
cd07786 (FGGY_EcGK_like)

245Q

glycerol binding site
11T, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 269F
CDD
cd07786 (FGGY_EcGK_like)

269F

glycerol binding site
11T, 80Q, 81R, 82E, 101W, 134Y, 244D, 245Q, 269F
CDD
cd07786 (FGGY_EcGK_like)
homotetramer inter...

31K

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

48M

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

51W

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

52S

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

56G

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

59S

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

60E

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

93K

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

171K

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

174N

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

227N

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)

228L

homotetramer interface
31K, 48M, 51W, 52S, 56G, 59S, 60E, 93K, 171K, 174N, 227N, 228L
CDD
cd07786 (FGGY_EcGK_like)
homodimer interfac...

37Y

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

40E

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

43V

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

102Q

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

307V

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

310A

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

313Q

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

314W

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

317D

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

340G

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

342Y

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

347F

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

360R

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

361G

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

362A

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

363I

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

364L

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

365G

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

366L

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

367T

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

368R

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

372K

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)

375I

homodimer interface
37Y, 40E, 43V, 102Q, 307V, 310A, 313Q, 314W, 317D, 340G, 342Y, 347F, 360R, 361G, 362A, 363I, 364L, 365G, 366L, 367T, 368R, 372K, 375I
CDD
cd07786 (FGGY_EcGK_like)
FBP binding site c...

232G

FBP binding site
232G, 233G, 235R
CDD
cd07786 (FGGY_EcGK_like)

233G

FBP binding site
232G, 233G, 235R
CDD
cd07786 (FGGY_EcGK_like)

235R

FBP binding site
232G, 233G, 235R
CDD
cd07786 (FGGY_EcGK_like)
protein IIAGlc int...

401K

protein IIAGlc interface
401K, 403N, 471P, 473M, 475K, 476E, 477E, 478R, 480K
CDD
cd07786 (FGGY_EcGK_like)

403N

protein IIAGlc interface
401K, 403N, 471P, 473M, 475K, 476E, 477E, 478R, 480K
CDD
cd07786 (FGGY_EcGK_like)

471P

protein IIAGlc interface
401K, 403N, 471P, 473M, 475K, 476E, 477E, 478R, 480K
CDD
cd07786 (FGGY_EcGK_like)

473M

protein IIAGlc interface
401K, 403N, 471P, 473M, 475K, 476E, 477E, 478R, 480K
CDD
cd07786 (FGGY_EcGK_like)

475K

protein IIAGlc interface
401K, 403N, 471P, 473M, 475K, 476E, 477E, 478R, 480K
CDD
cd07786 (FGGY_EcGK_like)

476E

protein IIAGlc interface
401K, 403N, 471P, 473M, 475K, 476E, 477E, 478R, 480K
CDD
cd07786 (FGGY_EcGK_like)

477E

protein IIAGlc interface
401K, 403N, 471P, 473M, 475K, 476E, 477E, 478R, 480K
CDD
cd07786 (FGGY_EcGK_like)

478R

protein IIAGlc interface
401K, 403N, 471P, 473M, 475K, 476E, 477E, 478R, 480K
CDD
cd07786 (FGGY_EcGK_like)

480K

protein IIAGlc interface
401K, 403N, 471P, 473M, 475K, 476E, 477E, 478R, 480K
CDD
cd07786 (FGGY_EcGK_like)

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0006072 glycerol-3-phosphate metabolic process

Molecular Function

GO:0004370 glycerol kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

23726_FusoPortal_Gene_717

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component