23726_FusoPortal_Gene_766

Protein

23726_FusoPortal_Gene_766

Length

328 amino acids

Protein family membership

3-oxoacyl-[acyl-carrier-protein] synthase 3 (IPR004655)

Homologous superfamilies

Homologous superfamily
2 - 327
Thiolase-like (IPR016039)

1 50 100 150 200 250 300 328

Domains and repeats

Domain
107 - 185
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III (IPR013751)
237 - 326
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal (IPR013747)

1 50 100 150 200 250 300 328

Detailed signature matches

IPR016039

Thiolase-like
1. SSF53901 (Thiolase-...)
  
  4 - 326
  
  SUPERFAMILY
  SSF53901 (Thiolase-like)
2. G3DSA:3.40.47.10
  
  2 - 171
  
  GENE3D
  G3DSA:3.40.47.10 (G3DSA:3.40.47.10)
  
  172 - 327
  
  GENE3D
  G3DSA:3.40.47.10 (G3DSA:3.40.47.10)
IPR004655

3-oxoacyl-[acyl-carrier-protein] synthase 3
1. TIGR00747
  
  4 - 326
  
  TIGRFAMs
  TIGR00747 (TIGR00747)
2. MF_01815 (FabH)
  
  2 - 326
  
  HAMAP
  MF_01815 (FabH)
IPR013751

3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
1. PF08545 (ACP_syn_III)
  
  107 - 185
  
  Pfam
  PF08545 (ACP_syn_III)
IPR013747

3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal
1. PF08541 (ACP_syn_III_C)
  
  237 - 326
  
  Pfam
  PF08541 (ACP_syn_III_C)

no IPR

Unintegrated signatures

PTHR43091 (FAMILY N...)

3 - 326

PANTHER
PTHR43091 (FAMILY NOT NAMED)
cd00830 (KAS_III)

3 - 324

CDD
cd00830 (KAS_III)

Residue annotation

dimer interface cd...

82T

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

84A

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

93C

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

96Q

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

104I

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

105P

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

106C

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

107F

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

108D

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

109L

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

110N

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

118Y

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

121E

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

122V

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

125S

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

126L

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

145R

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

181I

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

182G

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

183A

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

184E

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

185G

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

186E

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

192K

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

193V

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)

316G

dimer interface
82T, 84A, 93C, 96Q, 104I, 105P, 106C, 107F, 108D, 109L, 110N, 118Y, 121E, 122V, 125S, 126L, 145R, 181I, 182G, 183A, 184E, 185G, 186E, 192K, 193V, 316G
CDD
cd00830 (KAS_III)
active site cd00830

113C

active site
113C, 253H, 283N
CDD
cd00830 (KAS_III)

253H

active site
113C, 253H, 283N
CDD
cd00830 (KAS_III)

283N

active site
113C, 253H, 283N
CDD
cd00830 (KAS_III)
CoA binding pocket...

256N

CoA binding pocket
256N
CDD
cd00830 (KAS_III)

GO term prediction

Biological Process

GO:0006633 fatty acid biosynthetic process
GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

23726_FusoPortal_Gene_766

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component