23726_FusoPortal_Gene_861

Protein

23726_FusoPortal_Gene_861

Length

769 amino acids

Protein family membership

P-type ATPase (IPR001757)
- P-type ATPase, subfamily IB (IPR027256)

Homologous superfamilies

Homologous superfamily
17 - 86
Heavy metal-associated domain superfamily (IPR036163)
215 - 253
P-type ATPase, transmembrane domain superfamily (IPR023298)
350 - 452
P-type ATPase, transmembrane domain superfamily (IPR023298)
473 - 582
P-type ATPase, cytoplasmic domain N (IPR023299)
705 - 753
P-type ATPase, transmembrane domain superfamily (IPR023298)
Homologous superfamily
253 - 349
P-type ATPase, A domain superfamily (IPR008250)
456 - 476
HAD-like superfamily (IPR036412)
515 - 763
HAD-like superfamily (IPR036412)
Homologous superfamily
583 - 719
HAD superfamily (IPR023214)

1 100 200 300 400 500 600 700 769

Domains and repeats

Domain
21 - 87
Heavy metal-associated domain, HMA (IPR006121)

1 100 200 300 400 500 600 700 769

Detailed signature matches

IPR036163

Heavy metal-associated domain superfamily
1. SSF55008 (HMA, heav...)
  
  17 - 86
  
  SUPERFAMILY
  SSF55008 (HMA, heavy metal-associated domain)
IPR023298

P-type ATPase, transmembrane domain superfamily
1. SSF81665 (Calcium A...)
  
  215 - 253
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
  
  350 - 452
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
  
  705 - 753
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
IPR008250

P-type ATPase, A domain superfamily
1. SSF81653 (Calcium A...)
  
  253 - 349
  
  SUPERFAMILY
  SSF81653 (Calcium ATPase, transduction domain A)
IPR036412

HAD-like superfamily
1. SSF56784 (HAD-like)
  
  515 - 763
  
  SUPERFAMILY
  SSF56784 (HAD-like)
  
  456 - 476
  
  SUPERFAMILY
  SSF56784 (HAD-like)
IPR023299

P-type ATPase, cytoplasmic domain N
1. G3DSA:3.40.11...
  
  473 - 582
  
  GENE3D
  G3DSA:3.40.1110.10 (G3DSA:3.40.1110.10)
IPR023214

HAD superfamily
1. G3DSA:3.40.50...
  
  583 - 719
  
  GENE3D
  G3DSA:3.40.50.1000 (G3DSA:3.40.50.1000)
IPR001757

P-type ATPase
1. TIGR01494
  
  221 - 736
  
  TIGRFAMs
  TIGR01494 (TIGR01494)
IPR027256

P-type ATPase, subfamily IB
1. TIGR01525
  
  180 - 765
  
  TIGRFAMs
  TIGR01525 (TIGR01525)
IPR006121

Heavy metal-associated domain, HMA
1. PS50846 (HMA_2)
  
  21 - 87
  
  PROSITE profiles
  PS50846 (HMA_2)
2. PF00403 (HMA)
  
  24 - 84
  
  Pfam
  PF00403 (HMA)
3. cd00371 (HMA)
  
  23 - 86
  
  CDD
  cd00371 (HMA)
IPR018303

P-type ATPase, phosphorylation site
1. PS00154 (ATPASE_E1_E2)
  
  460 - 466
  
  PROSITE patterns
  PS00154 (ATPASE_E1_E2)

no IPR

Unintegrated signatures

G3DSA:1.20.11...

208 - 472

GENE3D
G3DSA:1.20.1110.10 (G3DSA:1.20.1110.10)
G3DSA:3.30.70...

18 - 97

GENE3D
G3DSA:3.30.70.100 (G3DSA:3.30.70.100)
PF00122 (E1-E2_ATPase)

251 - 436

Pfam
PF00122 (E1-E2_ATPase)
PF00702 (Hydrolase)

454 - 670

Pfam
PF00702 (Hydrolase)
PR00119 (CATATPASE)

458 - 472

PRINTS
PR00119 (CATATPASE)

603 - 613

PRINTS
PR00119 (CATATPASE)

656 - 675

PRINTS
PR00119 (CATATPASE)

679 - 691

PRINTS
PR00119 (CATATPASE)

299 - 313

PRINTS
PR00119 (CATATPASE)
PR00943 (CUATPASE)

165 - 184

PRINTS
PR00943 (CUATPASE)

219 - 238

PRINTS
PR00943 (CUATPASE)

633 - 650

PRINTS
PR00943 (CUATPASE)

145 - 163

PRINTS
PR00943 (CUATPASE)

65 - 85

PRINTS
PR00943 (CUATPASE)

690 - 704

PRINTS
PR00943 (CUATPASE)

36 - 50

PRINTS
PR00943 (CUATPASE)

372 - 386

PRINTS
PR00943 (CUATPASE)

441 - 456

PRINTS
PR00943 (CUATPASE)
PTHR43520 (FAMILY N...)

17 - 769

PANTHER
PTHR43520 (FAMILY NOT NAMED)
PTHR43520:SF8 (ATP7...)

17 - 769

PANTHER
PTHR43520:SF8 (ATP7, ISOFORM B)
SFLDF00027 (p-type_...)

439 - 708

SFLD
SFLDF00027 (p-type_atpase)
SFLDG00002 (C1.7:_P...)

439 - 708

SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
TIGR01511

161 - 766

TIGRFAMs
TIGR01511 (TIGR01511)
cd02094 (P-type_ATP...)

113 - 767

CDD
cd02094 (P-type_ATPase_Cu-like)

Residue annotation

metal-binding site...

29I

metal-binding site
29I, 30S, 31C, 34C
CDD
cd00371 (HMA)

30S

metal-binding site
29I, 30S, 31C, 34C
CDD
cd00371 (HMA)

31C

metal-binding site
29I, 30S, 31C, 34C
CDD
cd00371 (HMA)

34C

metal-binding site
29I, 30S, 31C, 34C
CDD
cd00371 (HMA)
HM-ATPase signatur...

416C

HM-ATPase signature motif
416C, 417P, 418C
CDD
cd02094 (P-type_ATPase_Cu-like)

417P

HM-ATPase signature motif
416C, 417P, 418C
CDD
cd02094 (P-type_ATPase_Cu-like)

418C

HM-ATPase signature motif
416C, 417P, 418C
CDD
cd02094 (P-type_ATPase_Cu-like)
putative Cu bindin...

416C

putative Cu binding site
416C, 418C, 722Y
CDD
cd02094 (P-type_ATPase_Cu-like)

418C

putative Cu binding site
416C, 418C, 722Y
CDD
cd02094 (P-type_ATPase_Cu-like)

722Y

putative Cu binding site
416C, 418C, 722Y
CDD
cd02094 (P-type_ATPase_Cu-like)
phosphorylation si...

460D

phosphorylation site
460D
CDD
cd02094 (P-type_ATPase_Cu-like)
P-type ATPase sign...

460D

P-type ATPase signature motif
460D, 461K, 462T, 463G, 464T, 465L, 466T
CDD
cd02094 (P-type_ATPase_Cu-like)

461K

P-type ATPase signature motif
460D, 461K, 462T, 463G, 464T, 465L, 466T
CDD
cd02094 (P-type_ATPase_Cu-like)

462T

P-type ATPase signature motif
460D, 461K, 462T, 463G, 464T, 465L, 466T
CDD
cd02094 (P-type_ATPase_Cu-like)

463G

P-type ATPase signature motif
460D, 461K, 462T, 463G, 464T, 465L, 466T
CDD
cd02094 (P-type_ATPase_Cu-like)

464T

P-type ATPase signature motif
460D, 461K, 462T, 463G, 464T, 465L, 466T
CDD
cd02094 (P-type_ATPase_Cu-like)

465L

P-type ATPase signature motif
460D, 461K, 462T, 463G, 464T, 465L, 466T
CDD
cd02094 (P-type_ATPase_Cu-like)

466T

P-type ATPase signature motif
460D, 461K, 462T, 463G, 464T, 465L, 466T
CDD
cd02094 (P-type_ATPase_Cu-like)
putative ATP bindi...

460D

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

461K

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

462T

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

525I

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

541L

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

542G

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

543N

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

571I

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

611T

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

612G

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

613D

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

633E

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

636P

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

639K

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

658D

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)

661N

putative ATP binding site
460D, 461K, 462T, 525I, 541L, 542G, 543N, 571I, 611T, 612G, 613D, 633E, 636P, 639K, 658D, 661N
CDD
cd02094 (P-type_ATPase_Cu-like)
SFLDF00027

460D

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDF00027 (p-type_atpase)

461K

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDF00027 (p-type_atpase)

462T

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDF00027 (p-type_atpase)

463G

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDF00027 (p-type_atpase)

464T

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDF00027 (p-type_atpase)

611T

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDF00027 (p-type_atpase)

639K

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDF00027 (p-type_atpase)

658D

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDF00027 (p-type_atpase)

662D

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDF00027 (p-type_atpase)
SFLDG00002

460D

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

461K

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

462T

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

463G

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

464T

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

611T

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

639K

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

658D

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

662D

SFLD_Res01
460D, 461K, 462T, 463G, 464T, 611T, 639K, 658D, 662D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
putative Cu bindin...

723N

putative Cu binding site
723N, 751M, 755S
CDD
cd02094 (P-type_ATPase_Cu-like)

751M

putative Cu binding site
723N, 751M, 755S
CDD
cd02094 (P-type_ATPase_Cu-like)

755S

putative Cu binding site
723N, 751M, 755S
CDD
cd02094 (P-type_ATPase_Cu-like)

GO term prediction

Biological Process

GO:0006812 cation transport
GO:0030001 metal ion transport

Molecular Function

GO:0000166 nucleotide binding
GO:0019829 cation-transporting ATPase activity
GO:0046872 metal ion binding

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features

23726_FusoPortal_Gene_861

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component