23726_FusoPortal_Gene_986

Protein

23726_FusoPortal_Gene_986

Length

477 amino acids

Protein family membership

Fumarate lyase family (IPR000362)
- Adenylosuccinate lyase (IPR004769)

Homologous superfamilies

Homologous superfamily
5 - 102
Fumarase/histidase, N-terminal (IPR024083)
Homologous superfamily
9 - 455
L-Aspartase-like (IPR008948)

1 50 100 150 200 250 300 350 400 450 477

Domains and repeats

Domain
98 - 304
Fumarate lyase, N-terminal (IPR022761)
371 - 453
Adenylosuccinate lyase C-terminal (IPR019468)

1 50 100 150 200 250 300 350 400 450 477

Detailed signature matches

IPR024083

Fumarase/histidase, N-terminal
1. G3DSA:1.10.27...
  
  5 - 102
  
  GENE3D
  G3DSA:1.10.275.10 (G3DSA:1.10.275.10)
IPR008948

L-Aspartase-like
1. SSF48557 (L-asparta...)
  
  9 - 455
  
  SUPERFAMILY
  SSF48557 (L-aspartase-like)
IPR000362

Fumarate lyase family
1. PR00149 (FUMRATELYASE)
  
  144 - 162
  
  PRINTS
  PR00149 (FUMRATELYASE)
  
  238 - 265
  
  PRINTS
  PR00149 (FUMRATELYASE)
  
  281 - 297
  
  PRINTS
  PR00149 (FUMRATELYASE)
IPR004769

Adenylosuccinate lyase
1. TIGR00928
  
  11 - 453
  
  TIGRFAMs
  TIGR00928 (TIGR00928)
IPR022761

Fumarate lyase, N-terminal
1. PF00206 (Lyase_1)
  
  98 - 304
  
  Pfam
  PF00206 (Lyase_1)
IPR019468

Adenylosuccinate lyase C-terminal
1. PF10397 (ADSL_C)
  
  371 - 453
  
  Pfam
  PF10397 (ADSL_C)
IPR020557

Fumarate lyase, conserved site
1. PS00163 (FUMARATE_L...)
  
  281 - 290
  
  PROSITE patterns
  PS00163 (FUMARATE_LYASES)

no IPR

Unintegrated signatures

Coil

477 - 477

COILS
Coil (Coil)
G3DSA:1.20.20...

103 - 474

GENE3D
G3DSA:1.20.200.10 (G3DSA:1.20.200.10)
PTHR43172 (FAMILY N...)

1 - 476

PANTHER
PTHR43172 (FAMILY NOT NAMED)
cd03302 (Adenylsucc...)

10 - 445

CDD
cd03302 (Adenylsuccinate_lyase_2)

Residue annotation

tetramer interface...

24S

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

25P

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

80D

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

89G

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

98I

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

99I

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

101L

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

102G

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

150F

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

151T

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

152H

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

153F

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

154Q

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

155A

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

157Q

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

163K

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

164R

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

167L

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

170Q

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

171S

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

177E

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

178E

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

194T

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

195T

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

196G

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

197T

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

200S

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

229F

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

231V

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

232T

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

239K

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

243E

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

250N

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

257K

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

261D

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

263R

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

264L

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

266Q

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

267H

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

289R

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

290N

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

295E

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

299S

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

302K

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

303F

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

305I

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

306A

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

309Q

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

310S

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

313M

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

314V

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

318Q

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

319W

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

320F

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

321E

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

322R

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

323T

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

324L

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

328A

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

329N

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

331R

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

336Q

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

376E

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

380M

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

383V

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

389R

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

390Q

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

443I

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)

445F

tetramer interface
24S, 25P, 80D, 89G, 98I, 99I, 101L, 102G, 150F, 151T, 152H, 153F, 154Q, 155A, 157Q, 163K, 164R, 167L, 170Q, 171S, 177E, 178E, 194T, 195T, 196G, 197T, 200S, 229F, 231V, 232T, 239K, 243E, 250N, 257K, 261D, 263R, 264L, 266Q, 267H, 289R, 290N, 295E, 299S, 302K, 303F, 305I, 306A, 309Q, 310S, 313M, 314V, 318Q, 319W, 320F, 321E, 322R, 323T, 324L, 328A, 329N, 331R, 336Q, 376E, 380M, 383V, 389R, 390Q, 443I, 445F
CDD
cd03302 (Adenylsuccinate_lyase_2)
active site cd03302

79H

active site
79H, 100H, 152H, 234Q, 288K, 290N, 295E
CDD
cd03302 (Adenylsuccinate_lyase_2)

100H

active site
79H, 100H, 152H, 234Q, 288K, 290N, 295E
CDD
cd03302 (Adenylsuccinate_lyase_2)

152H

active site
79H, 100H, 152H, 234Q, 288K, 290N, 295E
CDD
cd03302 (Adenylsuccinate_lyase_2)

234Q

active site
79H, 100H, 152H, 234Q, 288K, 290N, 295E
CDD
cd03302 (Adenylsuccinate_lyase_2)

288K

active site
79H, 100H, 152H, 234Q, 288K, 290N, 295E
CDD
cd03302 (Adenylsuccinate_lyase_2)

290N

active site
79H, 100H, 152H, 234Q, 288K, 290N, 295E
CDD
cd03302 (Adenylsuccinate_lyase_2)

295E

active site
79H, 100H, 152H, 234Q, 288K, 290N, 295E
CDD
cd03302 (Adenylsuccinate_lyase_2)

GO term prediction

Biological Process

GO:0009152 purine ribonucleotide biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

23726_FusoPortal_Gene_986

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component