25563_FusoPortal_Gene_1176

Protein

25563_FusoPortal_Gene_1176

Length

1,225 amino acids

Protein family membership

Phosphoribosylformylglycinamidine synthase, FGAM (IPR010141)

Homologous superfamilies

Homologous superfamily
191 - 411
PurM-like, N-terminal domain superfamily (IPR036921)
412 - 585
PurM-like, C-terminal domain superfamily (IPR036676)
595 - 789
PurM-like, N-terminal domain superfamily (IPR036921)
792 - 932
PurM-like, C-terminal domain superfamily (IPR036676)
960 - 1,225
Class I glutamine amidotransferase-like (IPR029062)

1 200 400 600 800 1000 1225

Domains and repeats

Domain
418 - 569
PurM-like, C-terminal domain (IPR010918)
964 - 1,225
Glutamine amidotransferase (IPR017926)

1 200 400 600 800 1000 1225

Detailed signature matches

IPR036921

PurM-like, N-terminal domain superfamily
1. SSF55326 (PurM N-te...)
  
  191 - 217
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
  
  281 - 408
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
  
  606 - 789
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
2. G3DSA:3.30.13...
  
  595 - 788
  
  GENE3D
  G3DSA:3.30.1330.10 (G3DSA:3.30.1330.10)
  
  191 - 411
  
  GENE3D
  G3DSA:3.30.1330.10 (G3DSA:3.30.1330.10)
IPR036676

PurM-like, C-terminal domain superfamily
1. SSF56042 (PurM C-te...)
  
  418 - 583
  
  SUPERFAMILY
  SSF56042 (PurM C-terminal domain-like)
  
  792 - 864
  
  SUPERFAMILY
  SSF56042 (PurM C-terminal domain-like)
2. G3DSA:3.90.65...
  
  412 - 585
  
  GENE3D
  G3DSA:3.90.650.10 (G3DSA:3.90.650.10)
  
  794 - 932
  
  GENE3D
  G3DSA:3.90.650.10 (G3DSA:3.90.650.10)
IPR029062

Class I glutamine amidotransferase-like
1. G3DSA:3.40.50...
  
  961 - 1,225
  
  GENE3D
  G3DSA:3.40.50.880 (G3DSA:3.40.50.880)
2. SSF52317 (Class I g...)
  
  960 - 1,224
  
  SUPERFAMILY
  SSF52317 (Class I glutamine amidotransferase-like)
IPR010141

Phosphoribosylformylglycinamidine synthase, FGAM
1. TIGR01857
  
  5 - 1,224
  
  TIGRFAMs
  TIGR01857 (TIGR01857)
IPR010918

PurM-like, C-terminal domain
1. PF02769 (AIRS_C)
  
  418 - 569
  
  Pfam
  PF02769 (AIRS_C)
IPR017926

Glutamine amidotransferase
1. PS51273 (GATASE_TYPE_1)
  
  964 - 1,225
  
  PROSITE profiles
  PS51273 (GATASE_TYPE_1)

no IPR

Unintegrated signatures

PF13507 (GATase_5)

962 - 1,224

Pfam
PF13507 (GATase_5)
PTHR10099 (PHOSPHOR...)

3 - 1,224

PANTHER
PTHR10099 (PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE)
PTHR10099:SF1 (PHOS...)

3 - 1,224

PANTHER
PTHR10099:SF1 (PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE)
cd01740 (GATase1_FG...)

965 - 1,221

CDD
cd01740 (GATase1_FGAR_AT)
cd02203 (PurL_repeat1)

200 - 577

CDD
cd02203 (PurL_repeat1)
cd02204 (PurL_repeat2)

660 - 897

CDD
cd02204 (PurL_repeat2)

Residue annotation

dimerization inter...

295L

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

296L

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

297M

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

298F

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

300N

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

325D

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

335Q

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

338R

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

341G

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

385S

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

396R

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

397M

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)

401A

dimerization interface
295L, 296L, 297M, 298F, 300N, 325D, 335Q, 338R, 341G, 385S, 396R, 397M, 401A
CDD
cd02203 (PurL_repeat1)
ATP binding site c...

321G

ATP binding site
321G, 325D, 383L, 384V, 385S
CDD
cd02203 (PurL_repeat1)

325D

ATP binding site
321G, 325D, 383L, 384V, 385S
CDD
cd02203 (PurL_repeat1)

383L

ATP binding site
321G, 325D, 383L, 384V, 385S
CDD
cd02203 (PurL_repeat1)

384V

ATP binding site
321G, 325D, 383L, 384V, 385S
CDD
cd02203 (PurL_repeat1)

385S

ATP binding site
321G, 325D, 383L, 384V, 385S
CDD
cd02203 (PurL_repeat1)
dimerization inter...

676A

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

677S

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

678A

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

679I

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

681W

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

706K

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

719L

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

722Q

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

725F

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

760K

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

774P

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

775T

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)

779F

dimerization interface
676A, 677S, 678A, 679I, 681W, 706K, 719L, 722Q, 725F, 760K, 774P, 775T, 779F
CDD
cd02204 (PurL_repeat2)
ATP binding site c...

702E

ATP binding site
702E, 706K, 758G, 759G, 760K
CDD
cd02204 (PurL_repeat2)

706K

ATP binding site
702E, 706K, 758G, 759G, 760K
CDD
cd02204 (PurL_repeat2)

758G

ATP binding site
702E, 706K, 758G, 759G, 760K
CDD
cd02204 (PurL_repeat2)

759G

ATP binding site
702E, 706K, 758G, 759G, 760K
CDD
cd02204 (PurL_repeat2)

760K

ATP binding site
702E, 706K, 758G, 759G, 760K
CDD
cd02204 (PurL_repeat2)
putative active si...

1,025G

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,026F

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,030D

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,066C

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,070Q

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,132S

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,133H

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,194M

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,196H

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,197S

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,198E

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)

1,199R

putative active site
1,025G, 1,026F, 1,030D, 1,066C, 1,070Q, 1,132S, 1,133H, 1,194M, 1,196H, 1,197S, 1,198E, 1,199R
CDD
cd01740 (GATase1_FGAR_AT)
catalytic triad cd...

1,066C

catalytic triad
1,066C, 1,196H, 1,198E
CDD
cd01740 (GATase1_FGAR_AT)

1,196H

catalytic triad
1,066C, 1,196H, 1,198E
CDD
cd01740 (GATase1_FGAR_AT)

1,198E

catalytic triad
1,066C, 1,196H, 1,198E
CDD
cd01740 (GATase1_FGAR_AT)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

25563_FusoPortal_Gene_1176

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component