25563_FusoPortal_Gene_1480

Protein

25563_FusoPortal_Gene_1480

Length

368 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
1 - 152
NAD(P)-binding domain superfamily (IPR036291)
179 - 363
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 250 300 368

Domains and repeats

Domain
5 - 286
NAD-dependent epimerase/dehydratase (IPR001509)

1 50 100 150 200 250 300 368

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  1 - 152
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
  
  179 - 363
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR001509

NAD-dependent epimerase/dehydratase
1. PF01370 (Epimerase)
  
  5 - 286
  
  Pfam
  PF01370 (Epimerase)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

1 - 266

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
G3DSA:3.90.25.10

267 - 365

GENE3D
G3DSA:3.90.25.10 (G3DSA:3.90.25.10)
PTHR43000 (FAMILY N...)

1 - 362

PANTHER
PTHR43000 (FAMILY NOT NAMED)
PTHR43000:SF13 (SUB...)

1 - 362

PANTHER
PTHR43000:SF13 (SUBFAMILY NOT NAMED)
cd05246 (dTDP_GD_SDR_e)

2 - 360

CDD
cd05246 (dTDP_GD_SDR_e)

Residue annotation

NAD binding site c...

8G

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

10A

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

11G

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

12F

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

13I

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

34D

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

35K

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

36L

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

37T

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

39A

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

40A

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

59G

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

60D

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

61I

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

82F

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

83A

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

84A

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

86S

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

101T

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

138I

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

139S

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

140T

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

194Y

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

198K

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

221C

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

222S

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

223N

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)

224N

NAD binding site
8G, 10A, 11G, 12F, 13I, 34D, 35K, 36L, 37T, 39A, 40A, 59G, 60D, 61I, 82F, 83A, 84A, 86S, 101T, 138I, 139S, 140T, 194Y, 198K, 221C, 222S, 223N, 224N
CDD
cd05246 (dTDP_GD_SDR_e)
substrate binding ...

86S

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

87H

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

88V

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

140T

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

141D

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

142E

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

194Y

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

221C

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

222S

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

223N

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

232E

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

233K

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

234L

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

237L

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

238M

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

249P

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

250V

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

251Y

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

256N

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

258R

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

293N

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

323R

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

326H

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)

330Y

substrate binding site
86S, 87H, 88V, 140T, 141D, 142E, 194Y, 221C, 222S, 223N, 232E, 233K, 234L, 237L, 238M, 249P, 250V, 251Y, 256N, 258R, 293N, 323R, 326H, 330Y
CDD
cd05246 (dTDP_GD_SDR_e)
homodimer interfac...

90R

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

92I

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

95P

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

96R

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

99L

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

103I

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

104L

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

107Q

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

111D

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

114R

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

146S

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

185E

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

187P

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

188V

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

190P

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

191N

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

192S

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

193P

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

196V

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

199T

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

200S

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

203L

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

204L

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

207A

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

208Y

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

210E

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

211T

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

212Y

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)

327D

homodimer interface
90R, 92I, 95P, 96R, 99L, 103I, 104L, 107Q, 111D, 114R, 146S, 185E, 187P, 188V, 190P, 191N, 192S, 193P, 196V, 199T, 200S, 203L, 204L, 207A, 208Y, 210E, 211T, 212Y, 327D
CDD
cd05246 (dTDP_GD_SDR_e)
active site cd05246

102N

active site
102N, 140T, 194Y, 198K
CDD
cd05246 (dTDP_GD_SDR_e)

140T

active site
102N, 140T, 194Y, 198K
CDD
cd05246 (dTDP_GD_SDR_e)

194Y

active site
102N, 140T, 194Y, 198K
CDD
cd05246 (dTDP_GD_SDR_e)

198K

active site
102N, 140T, 194Y, 198K
CDD
cd05246 (dTDP_GD_SDR_e)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity
GO:0050662 coenzyme binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

25563_FusoPortal_Gene_1480

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component