25563_FusoPortal_Gene_250

Protein

25563_FusoPortal_Gene_250

Length

337 amino acids

Protein family membership

Phenylalanyl-tRNA synthetase, class IIc, alpha subunit (IPR004529)
- Phenylalanine-tRNA ligase alpha chain 1, bacterial (IPR022911)

Homologous superfamilies

Homologous superfamily
15 - 100
Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm (IPR010978)

1 50 100 150 200 250 300 337

Domains and repeats

Domain
21 - 88
Phenylalanine-tRNA ligase, class II, N-terminal (IPR004188)
93 - 337
Phenylalanyl-tRNA synthetase (IPR002319)
Domain
116 - 328
Aminoacyl-tRNA synthetase, class II (IPR006195)

1 50 100 150 200 250 300 337

Detailed signature matches

IPR010978

Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm
1. SSF46589 (tRNA-bind...)
  
  15 - 100
  
  SUPERFAMILY
  SSF46589 (tRNA-binding arm)
IPR004529

Phenylalanyl-tRNA synthetase, class IIc, alpha subunit
1. TIGR00468
  
  39 - 337
  
  TIGRFAMs
  TIGR00468 (TIGR00468)
IPR022911

Phenylalanine-tRNA ligase alpha chain 1, bacterial
1. MF_00281 (Phe_tRNA_...)
  
  9 - 337
  
  HAMAP
  MF_00281 (Phe_tRNA_synth_alpha1)
2. PTHR11538:SF48 (PHE...)
  
  1 - 337
  
  PANTHER
  PTHR11538:SF48 (PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT)
IPR004188

Phenylalanine-tRNA ligase, class II, N-terminal
1. PF02912 (Phe_tRNA-s...)
  
  21 - 88
  
  Pfam
  PF02912 (Phe_tRNA-synt_N)
IPR002319

Phenylalanyl-tRNA synthetase
1. PF01409 (tRNA-synt_2d)
  
  93 - 337
  
  Pfam
  PF01409 (tRNA-synt_2d)
IPR006195

Aminoacyl-tRNA synthetase, class II
1. PS50862 (AA_TRNA_LI...)
  
  116 - 328
  
  PROSITE profiles
  PS50862 (AA_TRNA_LIGASE_II)

no IPR

Unintegrated signatures

G3DSA:3.30.93...

8 - 337

GENE3D
G3DSA:3.30.930.10 (G3DSA:3.30.930.10)
PTHR11538 (PHENYLAL...)

1 - 337

PANTHER
PTHR11538 (PHENYLALANYL-TRNA SYNTHETASE)
SSF55681 (Class II ...)

93 - 337

SUPERFAMILY
SSF55681 (Class II aaRS and biotin synthetases)
cd00496 (PheRS_alph...)

108 - 332

CDD
cd00496 (PheRS_alpha_core)

Residue annotation

dimer interface cd...

108H

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

111T

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

114M

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

115N

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

122I

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

127D

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

128V

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

130D

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

131G

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

132P

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

149S

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

154D

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

158T

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

159F

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

160Y

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

161M

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

162N

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

163P

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

178Y

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

185P

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

186F

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

187R

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

191P

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

193K

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

195Y

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

197P

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

204T

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

221F

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

222A

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

223D

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

225K

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

226G

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

245P

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

252E

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

253P

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

254S

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

256E

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

287D

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

288P

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

327F

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

329N

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

330D

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)

331I

dimer interface
108H, 111T, 114M, 115N, 122I, 127D, 128V, 130D, 131G, 132P, 149S, 154D, 158T, 159F, 160Y, 161M, 162N, 163P, 178Y, 185P, 186F, 187R, 191P, 193K, 195Y, 197P, 204T, 221F, 222A, 223D, 225K, 226G, 245P, 252E, 253P, 254S, 256E, 287D, 288P, 327F, 329N, 330D, 331I
CDD
cd00496 (PheRS_alpha_core)
motif 1 cd00496

126F

motif 1
126F, 127D, 128V, 129A, 130D, 131G, 132P
CDD
cd00496 (PheRS_alpha_core)

127D

motif 1
126F, 127D, 128V, 129A, 130D, 131G, 132P
CDD
cd00496 (PheRS_alpha_core)

128V

motif 1
126F, 127D, 128V, 129A, 130D, 131G, 132P
CDD
cd00496 (PheRS_alpha_core)

129A

motif 1
126F, 127D, 128V, 129A, 130D, 131G, 132P
CDD
cd00496 (PheRS_alpha_core)

130D

motif 1
126F, 127D, 128V, 129A, 130D, 131G, 132P
CDD
cd00496 (PheRS_alpha_core)

131G

motif 1
126F, 127D, 128V, 129A, 130D, 131G, 132P
CDD
cd00496 (PheRS_alpha_core)

132P

motif 1
126F, 127D, 128V, 129A, 130D, 131G, 132P
CDD
cd00496 (PheRS_alpha_core)
active site cd00496

154D

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

155L

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

156T

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

170Q

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

172S

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

175Q

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

196R

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

198D

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

202S

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

203H

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

204T

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

207F

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

209Q

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

211E

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

248F

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

250F

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

251T

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

279E

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

280I

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

281M

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

282G

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

283C

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

284G

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

306F

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

307G

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

308M

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

309G

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

312R

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)

323L

active site
154D, 155L, 156T, 170Q, 172S, 175Q, 196R, 198D, 202S, 203H, 204T, 207F, 209Q, 211E, 248F, 250F, 251T, 279E, 280I, 281M, 282G, 283C, 284G, 306F, 307G, 308M, 309G, 312R, 323L
CDD
cd00496 (PheRS_alpha_core)
motif 2 cd00496

195Y

motif 2
195Y, 196R, 197P, 198D
CDD
cd00496 (PheRS_alpha_core)

196R

motif 2
195Y, 196R, 197P, 198D
CDD
cd00496 (PheRS_alpha_core)

197P

motif 2
195Y, 196R, 197P, 198D
CDD
cd00496 (PheRS_alpha_core)

198D

motif 2
195Y, 196R, 197P, 198D
CDD
cd00496 (PheRS_alpha_core)
motif 3 cd00496

307G

motif 3
307G, 308M, 309G, 310I, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

308M

motif 3
307G, 308M, 309G, 310I, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

309G

motif 3
307G, 308M, 309G, 310I, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

310I

motif 3
307G, 308M, 309G, 310I, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

311E

motif 3
307G, 308M, 309G, 310I, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

312R

motif 3
307G, 308M, 309G, 310I, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

GO term prediction

Biological Process

GO:0006432 phenylalanyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation

Molecular Function

GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm

Filter view on

Entry type

Status

Per-residue features

25563_FusoPortal_Gene_250

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component