25563_FusoPortal_Gene_337

Protein

25563_FusoPortal_Gene_337

Length

371 amino acids

Protein family membership

Clp protease proteolytic subunit /Translocation-enhancing protein TepA (IPR023562)
- ATP-dependent Clp protease proteolytic subunit (IPR001907)

Homologous superfamilies

Homologous superfamily
4 - 192
ClpP/crotonase-like domain superfamily (IPR029045)

1 50 100 150 200 250 300 371

Domains and repeats

None predicted.

Detailed signature matches

IPR029045

ClpP/crotonase-like domain superfamily
1. SSF52096 (ClpP/crot...)
  
  4 - 192
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
IPR023562

Clp protease proteolytic subunit /Translocation-enhancing protein TepA
1. PF00574 (CLP_protease)
  
  44 - 187
  
  Pfam
  PF00574 (CLP_protease)
2. PTHR10381 (ATP-DEPE...)
  
  265 - 302
  
  PANTHER
  PTHR10381 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT)
  
  17 - 234
  
  PANTHER
  PTHR10381 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT)
IPR001907

ATP-dependent Clp protease proteolytic subunit
1. PR00127 (CLPPROTEASEP)
  
  165 - 184
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  89 - 106
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  54 - 74
  
  PRINTS
  PR00127 (CLPPROTEASEP)

no IPR

Unintegrated signatures

Coil

260 - 287

COILS
Coil (Coil)

211 - 231

COILS
Coil (Coil)
G3DSA:3.90.22...

1 - 203

GENE3D
G3DSA:3.90.226.10 (G3DSA:3.90.226.10)
PTHR10381:SF23 (SUB...)

265 - 302

PANTHER
PTHR10381:SF23 (SUBFAMILY NOT NAMED)

17 - 234

PANTHER
PTHR10381:SF23 (SUBFAMILY NOT NAMED)
cd07016 (S14_ClpP_1)

18 - 186

CDD
cd07016 (S14_ClpP_1)

Residue annotation

oligomer interface...

21R

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

23Y

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

40H

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

41S

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

44K

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

60N

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

67F

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

71A

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

74N

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

77K

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

78S

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

86E

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

94L

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

114G

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

116L

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

122P

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

123W

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

124T

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

125Y

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

132E

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

135Q

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

137I

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

139F

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

169E

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)

171W

oligomer interface
21R, 23Y, 40H, 41S, 44K, 60N, 67F, 71A, 74N, 77K, 78S, 86E, 94L, 114G, 116L, 122P, 123W, 124T, 125Y, 132E, 135Q, 137I, 139F, 169E, 171W
CDD
cd07016 (S14_ClpP_1)
active site residu...

97S

active site residues
97S, 120H, 169E
CDD
cd07016 (S14_ClpP_1)

120H

active site residues
97S, 120H, 169E
CDD
cd07016 (S14_ClpP_1)

169E

active site residues
97S, 120H, 169E
CDD
cd07016 (S14_ClpP_1)

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

25563_FusoPortal_Gene_337

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component