25563_FusoPortal_Gene_445

Protein

25563_FusoPortal_Gene_445

Length

239 amino acids

Protein family membership

Uridylate kinase (IPR011817)
- Uridylate kinase, bacteria (IPR015963)

Homologous superfamilies

Homologous superfamily
2 - 238
Acetylglutamate kinase-like superfamily (IPR036393)

1 50 100 150 200 239

Domains and repeats

Domain
8 - 216
Aspartate/glutamate/uridylate kinase (IPR001048)

1 50 100 150 200 239

Detailed signature matches

IPR036393

Acetylglutamate kinase-like superfamily
1. SSF53633 (Carbamate...)
  
  5 - 237
  
  SUPERFAMILY
  SSF53633 (Carbamate kinase-like)
2. G3DSA:3.40.11...
  
  2 - 238
  
  GENE3D
  G3DSA:3.40.1160.10 (G3DSA:3.40.1160.10)
IPR011817

Uridylate kinase
1. PIRSF005650 (Uridyl...)
  
  1 - 239
  
  PIRSF
  PIRSF005650 (Uridylate_kin)
IPR015963

Uridylate kinase, bacteria
1. TIGR02075
  
  6 - 236
  
  TIGRFAMs
  TIGR02075 (TIGR02075)
2. MF_01220_B (PyrH_B)
  
  4 - 237
  
  HAMAP
  MF_01220_B (PyrH_B)
IPR001048

Aspartate/glutamate/uridylate kinase
1. PF00696 (AA_kinase)
  
  8 - 216
  
  Pfam
  PF00696 (AA_kinase)

no IPR

Unintegrated signatures

PTHR42833 (FAMILY N...)

2 - 237

PANTHER
PTHR42833 (FAMILY NOT NAMED)
cd04254 (AAK_UMPK-P...)

7 - 236

CDD
cd04254 (AAK_UMPK-PyrH-Ec)

Residue annotation

putative nucleotid...

12K

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

15G

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

16E

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

53G

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

54G

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

55G

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

142T

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

143D

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

162T

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

163K

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

166G

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

168Y

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

170K

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

171D

putative nucleotide binding site
12K, 15G, 16E, 53G, 54G, 55G, 142T, 143D, 162T, 163K, 166G, 168Y, 170K, 171D
CDD
cd04254 (AAK_UMPK-PyrH-Ec)
uridine monophosph...

53G

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

54G

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

55G

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

59R

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

60G

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

74D

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

77G

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

78M

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

135T

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

137N

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

138P

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

140F

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

141T

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

142T

uridine monophosphate binding site
53G, 54G, 55G, 59R, 60G, 74D, 77G, 78M, 135T, 137N, 138P, 140F, 141T, 142T
CDD
cd04254 (AAK_UMPK-PyrH-Ec)
homohexameric inte...

66Q

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

67G

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

75H

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

76M

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

83I

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

90N

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

100R

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

114F

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

118K

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

121R

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

127R

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

135T

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

137N

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

138P

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

139Y

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

148L

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

151I

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

152E

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

208N

homohexameric interface
66Q, 67G, 75H, 76M, 83I, 90N, 100R, 114F, 118K, 121R, 127R, 135T, 137N, 138P, 139Y, 148L, 151I, 152E, 208N
CDD
cd04254 (AAK_UMPK-PyrH-Ec)

GO term prediction

Biological Process

GO:0006221 pyrimidine nucleotide biosynthetic process

Molecular Function

GO:0009041 uridylate kinase activity
GO:0033862 UMP kinase activity

Cellular Component

GO:0005737 cytoplasm

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Entry type

Status

Per-residue features

25563_FusoPortal_Gene_445

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component