25563_FusoPortal_Gene_503

Protein

25563_FusoPortal_Gene_503

Length

273 amino acids

Protein family membership

Pyridoxine kinase (IPR004625)

Homologous superfamilies

Homologous superfamily
1 - 256
Ribokinase-like (IPR029056)

1 50 100 150 200 273

Domains and repeats

Domain
70 - 253
Pyridoxamine kinase/Phosphomethylpyrimidine kinase (IPR013749)

1 50 100 150 200 273

Detailed signature matches

IPR029056

Ribokinase-like
1. G3DSA:3.40.11...
  
  1 - 255
  
  GENE3D
  G3DSA:3.40.1190.20 (G3DSA:3.40.1190.20)
2. SSF53613 (Ribokinas...)
  
  1 - 256
  
  SUPERFAMILY
  SSF53613 (Ribokinase-like)
IPR004625

Pyridoxine kinase
1. PTHR10534 (PYRIDOXA...)
  
  3 - 255
  
  PANTHER
  PTHR10534 (PYRIDOXAL KINASE)
2. cd01173 (pyridoxal_...)
  
  4 - 248
  
  CDD
  cd01173 (pyridoxal_pyridoxamine_kinase)
IPR013749

Pyridoxamine kinase/Phosphomethylpyrimidine kinase
1. PF08543 (Phos_pyr_kin)
  
  70 - 253
  
  Pfam
  PF08543 (Phos_pyr_kin)

Residue annotation

dimer interface cd...

4K

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

11M

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

13G

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

14Y

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

16K

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

20S

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

24P

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

27S

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

32S

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

33L

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

34F

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

35N

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

36L

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

37P

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

40L

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

43N

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

51E

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

52I

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

54D

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

61K

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

62S

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

69L

dimer interface
4K, 11M, 13G, 14Y, 16K, 20S, 24P, 27S, 32S, 33L, 34F, 35N, 36L, 37P, 40L, 43N, 51E, 52I, 54D, 61K, 62S, 69L
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)
pyridoxal binding ...

10D

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

17V

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

18A

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

41V

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

44T

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

45L

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

50F

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

80F

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

82F

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

215P

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

216G

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

219D

pyridoxal binding site
10D, 17V, 18A, 41V, 44T, 45L, 50F, 80F, 82F, 215P, 216G, 219D
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)
ATP binding site c...

107D

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

112D

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

139V

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

141N

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

144E

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

181T

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

182S

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

191Y

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

205L

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

207Y

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

208D

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

214F

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

217T

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

218G

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

219D

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

221F

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

246V

ATP binding site
107D, 112D, 139V, 141N, 144E, 181T, 182S, 191Y, 205L, 207Y, 208D, 214F, 217T, 218G, 219D, 221F, 246V
CDD
cd01173 (pyridoxal_pyridoxamine_kinase)

GO term prediction

Biological Process

GO:0009443 pyridoxal 5'-phosphate salvage

Molecular Function

GO:0008478 pyridoxal kinase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

25563_FusoPortal_Gene_503

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component