25563_FusoPortal_Gene_521

Protein

25563_FusoPortal_Gene_521

Length

259 amino acids

Protein family membership

NAD(+) synthetase (IPR003694)
- NH(3)-dependent NAD(+) synthetase (IPR022926)

Homologous superfamilies

Homologous superfamily
1 - 251
Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)

1 50 100 150 200 259

Domains and repeats

Domain
6 - 243
NAD/GMP synthase (IPR022310)

1 50 100 150 200 259

Detailed signature matches

IPR014729

Rossmann-like alpha/beta/alpha sandwich fold
1. G3DSA:3.40.50...
  
  1 - 251
  
  GENE3D
  G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
IPR003694

NAD(+) synthetase
1. TIGR00552
  
  3 - 247
  
  TIGRFAMs
  TIGR00552 (TIGR00552)
2. cd00553 (NAD_synthase)
  
  6 - 241
  
  CDD
  cd00553 (NAD_synthase)
3. PTHR23090 (NH 3 /GL...)
  
  6 - 251
  
  PANTHER
  PTHR23090 (NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE)
IPR022926

NH(3)-dependent NAD(+) synthetase
1. MF_00193 (NadE_ammo...)
  
  3 - 247
  
  HAMAP
  MF_00193 (NadE_ammonia_dep)
IPR022310

NAD/GMP synthase
1. PF02540 (NAD_synthase)
  
  6 - 243
  
  Pfam
  PF02540 (NAD_synthase)

no IPR

Unintegrated signatures

Coil

197 - 217

COILS
Coil (Coil)
SSF52402 (Adenine n...)

3 - 246

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)

Residue annotation

homodimer interfac...

7K

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

8L

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

11F

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

14E

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

15Q

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

78Q

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

79E

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

80K

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

81T

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

84I

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

85T

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

88V

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

89D

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

102R

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

106Y

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

109R

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

110T

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

112M

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

113T

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

114V

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

116F

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

117D

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

118Q

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

120A

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

121L

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

142L

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

143F

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

146M

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

147A

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

148C

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

149S

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

150F

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

151N

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

154G

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

155D

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

239Y

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)

241R

homodimer interface
7K, 8L, 11F, 14E, 15Q, 78Q, 79E, 80K, 81T, 84I, 85T, 88V, 89D, 102R, 106Y, 109R, 110T, 112M, 113T, 114V, 116F, 117D, 118Q, 120A, 121L, 142L, 143F, 146M, 147A, 148C, 149S, 150F, 151N, 154G, 155D, 239Y, 241R
CDD
cd00553 (NAD_synthase)
NAD binding pocket...

26L

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

27G

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

28L

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

29S

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

34S

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

53I

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

54K

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

55M

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

101L

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

105N

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

108A

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

109R

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

111R

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

129T

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

134E

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

139Y

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

140G

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

141T

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

142L

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

145D

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

180S

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

181A

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

183L

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

192E

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

239Y

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)

240K

NAD binding pocket
26L, 27G, 28L, 29S, 34S, 53I, 54K, 55M, 101L, 105N, 108A, 109R, 111R, 129T, 134E, 139Y, 140G, 141T, 142L, 145D, 180S, 181A, 183L, 192E, 239Y, 240K
CDD
cd00553 (NAD_synthase)
ATP binding pocket...

27G

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

28L

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

29S

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

33D

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

34S

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

54K

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

55M

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

111R

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

129T

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

158K

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

179P

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)

180S

ATP binding pocket
27G, 28L, 29S, 33D, 34S, 54K, 55M, 111R, 129T, 158K, 179P, 180S
CDD
cd00553 (NAD_synthase)
Mg binding site cd...

29S

Mg binding site
29S, 33D, 134E, 180S
CDD
cd00553 (NAD_synthase)

33D

Mg binding site
29S, 33D, 134E, 180S
CDD
cd00553 (NAD_synthase)

134E

Mg binding site
29S, 33D, 134E, 180S
CDD
cd00553 (NAD_synthase)

180S

Mg binding site
29S, 33D, 134E, 180S
CDD
cd00553 (NAD_synthase)
active-site loop c...

62Q

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

176E

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

177K

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

178Q

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

179P

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

180S

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

181A

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

182D

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

183L

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

186G

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

187Q

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

188T

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

189D

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

190E

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

191Q

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

192E

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

193L

active-site loop
62Q, 176E, 177K, 178Q, 179P, 180S, 181A, 182D, 183L, 186G, 187Q, 188T, 189D, 190E, 191Q, 192E, 193L
CDD
cd00553 (NAD_synthase)

GO term prediction

Biological Process

GO:0009435 NAD biosynthetic process

Molecular Function

GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0008795 NAD+ synthase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

25563_FusoPortal_Gene_521

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component