25563_FusoPortal_Gene_54

Protein

25563_FusoPortal_Gene_54

Length

253 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
1 - 248
Tetrapyrrole methylase superfamily (IPR035996)
Homologous superfamily
1 - 121
Tetrapyrrole methylase, subdomain 1 (IPR014777)
122 - 253
Tetrapyrrole methylase, subdomain 2 (IPR014776)

1 50 100 150 200 253

Domains and repeats

Domain
3 - 248
Tetrapyrrole methylase (IPR000878)
Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase (IPR006362)

1 50 100 150 200 253

Detailed signature matches

IPR014777

Tetrapyrrole methylase, subdomain 1
1. G3DSA:3.40.10...
  
  1 - 121
  
  GENE3D
  G3DSA:3.40.1010.10 (G3DSA:3.40.1010.10)
IPR035996

Tetrapyrrole methylase superfamily
1. SSF53790 (Tetrapyrr...)
  
  1 - 248
  
  SUPERFAMILY
  SSF53790 (Tetrapyrrole methylase)
IPR014776

Tetrapyrrole methylase, subdomain 2
1. G3DSA:3.30.95...
  
  122 - 253
  
  GENE3D
  G3DSA:3.30.950.10 (G3DSA:3.30.950.10)
IPR000878

Tetrapyrrole methylase
1. PF00590 (TP_methylase)
  
  3 - 208
  
  Pfam
  PF00590 (TP_methylase)
IPR006362

Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase
1. cd11641 (Precorrin-...)
  
  4 - 230
  
  CDD
  cd11641 (Precorrin-4_C11-MT)
2. TIGR01465
  
  4 - 248
  
  TIGRFAMs
  TIGR01465 (TIGR01465)
IPR003043

Uroporphiryn-III C-methyltransferase, conserved site
1. PS00839 (SUMT_1)
  
  7 - 21
  
  PROSITE patterns
  PS00839 (SUMT_1)

no IPR

Unintegrated signatures

PTHR21091 (METHYLTE...)

3 - 251

PANTHER
PTHR21091 (METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED)
PTHR21091:SF17 (SUB...)

3 - 251

PANTHER
PTHR21091:SF17 (SUBFAMILY NOT NAMED)

Residue annotation

active site cd11641

11P

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

82T

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

83G

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

84D

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

87I

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

88Y

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

89G

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

112S

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

113S

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

138R

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

163I

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

164F

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

190V

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

192R

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

193A

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

221A

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

222Q

active site
11P, 82T, 83G, 84D, 87I, 88Y, 89G, 112S, 113S, 138R, 163I, 164F, 190V, 192R, 193A, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)
SAM binding site c...

11P

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

37L

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

82T

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

83G

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

84D

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

87I

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

112S

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

113S

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

163I

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

164F

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

165L

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

190V

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

192R

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

193A

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

220T

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

221A

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)

222Q

SAM binding site
11P, 37L, 82T, 83G, 84D, 87I, 112S, 113S, 163I, 164F, 165L, 190V, 192R, 193A, 220T, 221A, 222Q
CDD
cd11641 (Precorrin-4_C11-MT)
homodimer interfac...

13D

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

15E

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

16L

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

17I

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

18T

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

19I

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

20K

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

22Q

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

60L

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

84D

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

85P

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

86A

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

87I

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

88Y

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

89G

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

90A

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

91H

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

92R

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

93E

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

95M

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

96D

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

99D

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

107V

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

109P

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

110G

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

111V

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

112S

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

114F

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

115L

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

118A

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

119A

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

122K

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

124E

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

125F

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

126T

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

130V

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

131S

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

132Q

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

133T

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

134V

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

135I

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

136C

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

137T

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

138R

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

145V

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

146P

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

148R

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

149E

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

153S

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

154L

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

156S

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

157H

homodimer interface
13D, 15E, 16L, 17I, 18T, 19I, 20K, 22Q, 60L, 84D, 85P, 86A, 87I, 88Y, 89G, 90A, 91H, 92R, 93E, 95M, 96D, 99D, 107V, 109P, 110G, 111V, 112S, 114F, 115L, 118A, 119A, 122K, 124E, 125F, 126T, 130V, 131S, 132Q, 133T, 134V, 135I, 136C, 137T, 138R, 145V, 146P, 148R, 149E, 153S, 154L, 156S, 157H
CDD
cd11641 (Precorrin-4_C11-MT)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0009236 cobalamin biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0008168 methyltransferase activity
GO:0046026 precorrin-4 C11-methyltransferase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

25563_FusoPortal_Gene_54

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component