25586_FusoPortal_Gene_1037

Protein

25586_FusoPortal_Gene_1037

Length

338 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
105 - 307
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 250 300 338

Domains and repeats

Domain
4 - 335
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (IPR006139)
Domain
114 - 305
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (IPR006140)

1 50 100 150 200 250 300 338

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  105 - 307
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR006139

D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
1. PF00389 (2-Hacid_dh)
  
  4 - 335
  
  Pfam
  PF00389 (2-Hacid_dh)
IPR006140

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
1. PF02826 (2-Hacid_dh_C)
  
  114 - 305
  
  Pfam
  PF02826 (2-Hacid_dh_C)
IPR029752

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1
1. PS00065 (D_2_HYDROX...)
  
  151 - 178
  
  PROSITE patterns
  PS00065 (D_2_HYDROXYACID_DH_1)
IPR029753

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site
1. PS00671 (D_2_HYDROX...)
  
  226 - 242
  
  PROSITE patterns
  PS00671 (D_2_HYDROXYACID_DH_3)

no IPR

Unintegrated signatures

Coil

233 - 253

COILS
Coil (Coil)
G3DSA:3.40.50...

2 - 118

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)

119 - 305

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PTHR43026 (FAMILY N...)

1 - 337

PANTHER
PTHR43026 (FAMILY NOT NAMED)
PTHR43026:SF2 (SUBF...)

1 - 337

PANTHER
PTHR43026:SF2 (SUBFAMILY NOT NAMED)
SSF52283 (Formate/g...)

2 - 138

SUPERFAMILY
SSF52283 (Formate/glycerate dehydrogenase catalytic domain-like)
cd12184 (HGDH_like)

1 - 336

CDD
cd12184 (HGDH_like)

Residue annotation

putative homodimer...

54R

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

104S

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

106N

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

107A

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

110E

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

111L

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

114S

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

117M

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

118S

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

121R

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

126T

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

127A

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

130F

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

142F

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

143S

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

145E

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

146V

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

147R

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

148N

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

166L

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

169G

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

170L

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

269Y

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

270F

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

300V

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

302P

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

303H

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

304V

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

305G

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

306S

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

307Y

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

308T

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

309D

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

310E

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)

312A

putative homodimer interface
54R, 104S, 106N, 107A, 110E, 111L, 114S, 117M, 118S, 121R, 126T, 127A, 130F, 142F, 143S, 145E, 146V, 147R, 148N, 166L, 169G, 170L, 269Y, 270F, 300V, 302P, 303H, 304V, 305G, 306S, 307Y, 308T, 309D, 310E, 312A
CDD
cd12184 (HGDH_like)
putative ligand bi...

79T

putative ligand binding site
79T, 80V, 81G, 103Y, 237R, 303H, 306S
CDD
cd12184 (HGDH_like)

80V

putative ligand binding site
79T, 80V, 81G, 103Y, 237R, 303H, 306S
CDD
cd12184 (HGDH_like)

81G

putative ligand binding site
79T, 80V, 81G, 103Y, 237R, 303H, 306S
CDD
cd12184 (HGDH_like)

103Y

putative ligand binding site
79T, 80V, 81G, 103Y, 237R, 303H, 306S
CDD
cd12184 (HGDH_like)

237R

putative ligand binding site
79T, 80V, 81G, 103Y, 237R, 303H, 306S
CDD
cd12184 (HGDH_like)

303H

putative ligand binding site
79T, 80V, 81G, 103Y, 237R, 303H, 306S
CDD
cd12184 (HGDH_like)

306S

putative ligand binding site
79T, 80V, 81G, 103Y, 237R, 303H, 306S
CDD
cd12184 (HGDH_like)
putative NAD bindi...

103Y

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

108I

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

155G

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

157G

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

158R

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

159I

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

160G

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

177Y

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

178D

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

179M

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

207H

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

208A

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

209P

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

210F

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

214N

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

217I

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

235T

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

236A

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

237R

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

261D

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

262T

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

303H

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

305G

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)

306S

putative NAD binding site
103Y, 108I, 155G, 157G, 158R, 159I, 160G, 177Y, 178D, 179M, 207H, 208A, 209P, 210F, 214N, 217I, 235T, 236A, 237R, 261D, 262T, 303H, 305G, 306S
CDD
cd12184 (HGDH_like)
catalytic site cd1...

237R

catalytic site
237R, 266E, 303H
CDD
cd12184 (HGDH_like)

266E

catalytic site
237R, 266E, 303H
CDD
cd12184 (HGDH_like)

303H

catalytic site
237R, 266E, 303H
CDD
cd12184 (HGDH_like)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

25586_FusoPortal_Gene_1037

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component