25586_FusoPortal_Gene_1591

Protein

25586_FusoPortal_Gene_1591

Length

336 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
6 - 312
Tryptophan synthase beta subunit-like PLP-dependent enzyme (IPR036052)

1 50 100 150 200 250 300 336

Domains and repeats

Domain
11 - 299
Pyridoxal-phosphate dependent enzyme (IPR001926)

1 50 100 150 200 250 300 336

Detailed signature matches

IPR036052

Tryptophan synthase beta subunit-like PLP-dependent enzyme
1. SSF53686 (Tryptopha...)
  
  6 - 312
  
  SUPERFAMILY
  SSF53686 (Tryptophan synthase beta subunit-like PLP-dependent enzymes)
IPR001926

Pyridoxal-phosphate dependent enzyme
1. PF00291 (PALP)
  
  11 - 299
  
  Pfam
  PF00291 (PALP)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

139 - 321

GENE3D
G3DSA:3.40.50.1100 (G3DSA:3.40.50.1100)

23 - 138

GENE3D
G3DSA:3.40.50.1100 (G3DSA:3.40.50.1100)
PTHR10314 (SER/THR ...)

4 - 314

PANTHER
PTHR10314 (SER/THR DEHYDRATASE, TRP SYNTHASE)
PTHR10314:SF159 (CY...)

4 - 314

PANTHER
PTHR10314:SF159 (CYSTEINE SYNTHASE A)
cd01561 (CBS_like)

14 - 306

CDD
cd01561 (CBS_like)

Residue annotation

dimer interface cd...

18M

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

19L

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

20E

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

33F

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

39Y

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

41L

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

83A

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

86A

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

102E

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

103E

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

106S

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

107L

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

110S

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

111F

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

167N

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

168E

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

263A

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

264K

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

265C

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

266G

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

267L

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

268G

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

292V

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

302K

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)

305L

dimer interface
18M, 19L, 20E, 33F, 39Y, 41L, 83A, 86A, 102E, 103E, 106S, 107L, 110S, 111F, 167N, 168E, 263A, 264K, 265C, 266G, 267L, 268G, 292V, 302K, 305L
CDD
cd01561 (CBS_like)
catalytic residue ...

46K

catalytic residue
46K
CDD
cd01561 (CBS_like)
pyridoxal 5'-phosp...

46K

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

76N

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

183V

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

184G

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

185T

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

186G

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

187G

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

188T

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

229G

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

272S

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

298P

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

299D

pyridoxal 5'-phosphate binding site
46K, 76N, 183V, 184G, 185T, 186G, 187G, 188T, 229G, 272S, 298P, 299D
CDD
cd01561 (CBS_like)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

25586_FusoPortal_Gene_1591

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component