25586_FusoPortal_Gene_174

Protein

25586_FusoPortal_Gene_174

Length

266 amino acids

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)

Homologous superfamilies

Homologous superfamily
9 - 265
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 266

Domains and repeats

None predicted.

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  9 - 265
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR002347

Short-chain dehydrogenase/reductase SDR
1. PR00080 (SDRFAMILY)
  
  174 - 193
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  87 - 98
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  140 - 148
  
  PRINTS
  PR00080 (SDRFAMILY)
2. PR00081 (GDHRDH)
  
  12 - 29
  
  PRINTS
  PR00081 (GDHRDH)
  
  134 - 150
  
  PRINTS
  PR00081 (GDHRDH)
  
  174 - 193
  
  PRINTS
  PR00081 (GDHRDH)
  
  195 - 212
  
  PRINTS
  PR00081 (GDHRDH)
  
  87 - 98
  
  PRINTS
  PR00081 (GDHRDH)
  
  227 - 247
  
  PRINTS
  PR00081 (GDHRDH)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

2 - 264

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PF13561 (adh_short_C2)

22 - 264

Pfam
PF13561 (adh_short_C2)
PTHR42760 (FAMILY N...)

9 - 265

PANTHER
PTHR42760 (FAMILY NOT NAMED)
cd08930 (SDR_c8)

9 - 262

CDD
cd08930 (SDR_c8)

Residue annotation

putative NAD(P) bi...

17G

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

19N

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

20G

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

21H

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

22L

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

41S

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

42R

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

43N

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

67L

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

68D

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

69L

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

95N

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

96S

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

97Y

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

118G

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

145I

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

146A

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

147S

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

174Y

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

178K

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

204P

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

205G

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

206P

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

207F

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

209N

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)

210F

putative NAD(P) binding site
17G, 19N, 20G, 21H, 22L, 41S, 42R, 43N, 67L, 68D, 69L, 95N, 96S, 97Y, 118G, 145I, 146A, 147S, 174Y, 178K, 204P, 205G, 206P, 207F, 209N, 210F
CDD
cd08930 (SDR_c8)
active site cd08930

119S

active site
119S, 147S, 174Y, 178K
CDD
cd08930 (SDR_c8)

147S

active site
119S, 147S, 174Y, 178K
CDD
cd08930 (SDR_c8)

174Y

active site
119S, 147S, 174Y, 178K
CDD
cd08930 (SDR_c8)

178K

active site
119S, 147S, 174Y, 178K
CDD
cd08930 (SDR_c8)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

25586_FusoPortal_Gene_174

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component