Filter view on
Entry type
Status
Per-residue features
Colour by
25586_FusoPortal_Gene_1804
Length
636 amino acids
Protein family membership
- Methionyl-tRNA synthetase (IPR014758)
- Methionine-tRNA synthetase, type 2 (IPR023457)
Homologous superfamilies
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Homologous superfamily2 - 345
- Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
354 - 520535 - 633- Nucleic acid-binding, OB-fold (IPR012340)
1
100
200
300
400
500
636
Domains and repeats
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Domain4 - 362
- Methionyl/Leucyl tRNA synthetase (IPR015413)
- Methioninyl-tRNA synthetase core domain (IPR033911)
383 - 520531 - 636- tRNA-binding domain (IPR002547)
- Methionyl/Leucyl tRNA synthetase (IPR015413)
1
100
200
300
400
500
636
Detailed signature matches

Unintegrated signatures
-
346 - 513
-
534 - 636
-
PTHR43326 (FAMILY N...)2 - 522
-
PTHR43326:SF3 (SUBF...)2 - 522
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SSF52374 (Nucleotid...)2 - 352
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cd07957 (Anticodon_...)346 - 475
Residue annotation
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active site cd0081410P11I13Y50D226W229A230L233Y263I267H
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HIGH motif cd00814
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KMSKS motif cd00814298K299M300S301K302S
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tRNA binding surfa...347NtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)354LtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)355GtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)358LtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)359NtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)362LtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)363GtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)366KtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)367KtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)370NtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)371GtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)421NtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)422KtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)424ItRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)425DtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met)430WtRNA binding surface
347N, 354L, 355G, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 421N, 422K, 424I, 425D, 430W
CDD
cd07957 (Anticodon_Ia_Met) -
anticodon binding ...354Lanticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met)358Lanticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met)359Nanticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met)362Lanticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met)363Ganticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met)366Kanticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met)367Kanticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met)370Nanticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met)371Ganticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met)424Ianticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met)430Wanticodon binding site
354L, 358L, 359N, 362L, 363G, 366K, 367K, 370N, 371G, 424I, 430W
CDD
cd07957 (Anticodon_Ia_Met) -
dimer interface cd...532Ddimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)579Fdimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)596Ndimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)597Ldimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)598Kdimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)601Kdimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)613Tdimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)614Tdimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)615Edimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)616Ddimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)622Ldimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)624Kdimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)626Ddimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)629Vdimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)633Adimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)634Idimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)635Vdimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like)636Sdimer interface
532D, 579F, 596N, 597L, 598K, 601K, 613T, 614T, 615E, 616D, 622L, 624K, 626D, 629V, 633A, 634I, 635V, 636S
CDD
cd02800 (tRNA_bind_EcMetRS_like) -
putative tRNA-bind...557K569E596N600T607S610M
GO term prediction
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006431 methionyl-tRNA aminoacylation
Molecular Function
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004825 methionine-tRNA ligase activity
GO:0005524 ATP binding
Cellular Component
GO:0005737 cytoplasm