25586_FusoPortal_Gene_512

Protein

25586_FusoPortal_Gene_512

Length

193 amino acids

Protein family membership

Clp protease proteolytic subunit /Translocation-enhancing protein TepA (IPR023562)
- ATP-dependent Clp protease proteolytic subunit (IPR001907)

Homologous superfamilies

Homologous superfamily
11 - 191
ClpP/crotonase-like domain superfamily (IPR029045)

1 20 40 60 80 100 120 140 160 180 193

Domains and repeats

None predicted.

Detailed signature matches

IPR029045

ClpP/crotonase-like domain superfamily
1. SSF52096 (ClpP/crot...)
  
  11 - 191
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
IPR023562

Clp protease proteolytic subunit /Translocation-enhancing protein TepA
1. PF00574 (CLP_protease)
  
  12 - 192
  
  Pfam
  PF00574 (CLP_protease)
2. PTHR10381 (ATP-DEPE...)
  
  8 - 191
  
  PANTHER
  PTHR10381 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT)
IPR001907

ATP-dependent Clp protease proteolytic subunit
1. MF_00444 (ClpP)
  
  2 - 193
  
  HAMAP
  MF_00444 (ClpP)
2. TIGR00493
  
  4 - 192
  
  TIGRFAMs
  TIGR00493 (TIGR00493)
3. PR00127 (CLPPROTEASEP)
  
  18 - 33
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  58 - 78
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  89 - 106
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  169 - 188
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  110 - 129
  
  PRINTS
  PR00127 (CLPPROTEASEP)
4. cd07017 (S14_ClpP_2)
  
  18 - 190
  
  CDD
  cd07017 (S14_ClpP_2)
IPR018215

ClpP, Ser active site
1. PS00381 (CLP_PROTEA...)
  
  89 - 100
  
  PROSITE patterns
  PS00381 (CLP_PROTEASE_SER)
IPR033135

ClpP, histidine active site
1. PS00382 (CLP_PROTEA...)
  
  111 - 124
  
  PROSITE patterns
  PS00382 (CLP_PROTEASE_HIS)

no IPR

Unintegrated signatures

G3DSA:3.90.22...

1 - 193

GENE3D
G3DSA:3.90.226.10 (G3DSA:3.90.226.10)

Residue annotation

oligomer interface...

30F

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

32G

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

41N

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

42S

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

45A

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

46Q

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

49Y

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

64N

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

71T

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

75A

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

78D

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

81N

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

82Y

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

86D

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

94Q

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

116N

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

118R

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

124P

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

127S

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

128G

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

129G

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

143E

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

146K

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

148K

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

150R

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

173D

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)

175Y

oligomer interface
30F, 32G, 41N, 42S, 45A, 46Q, 49Y, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116N, 118R, 124P, 127S, 128G, 129G, 143E, 146K, 148K, 150R, 173D, 175Y
CDD
cd07017 (S14_ClpP_2)
active site residu...

97S

active site residues
97S, 122H, 173D
CDD
cd07017 (S14_ClpP_2)

122H

active site residues
97S, 122H, 173D
CDD
cd07017 (S14_ClpP_2)

173D

active site residues
97S, 122H, 173D
CDD
cd07017 (S14_ClpP_2)

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

25586_FusoPortal_Gene_512

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component