25586_FusoPortal_Gene_663

Protein

25586_FusoPortal_Gene_663

Length

434 amino acids

Protein family membership

Ribonuclease PH, bacterial-type (IPR002381)

Ham1-like protein (IPR002637)
- dITP/XTP pyrophosphatase (IPR020922)

Homologous superfamilies

Homologous superfamily
1 - 231
PNPase/RNase PH domain superfamily (IPR027408)
Homologous superfamily
2 - 182
Ribosomal protein S5 domain 2-type fold (IPR020568)
232 - 433
Inosine triphosphate pyrophosphatase-like (IPR029001)
Homologous superfamily
154 - 238
Exoribonuclease, PH domain 2 superfamily (IPR036345)

1 50 100 150 200 250 300 350 400 434

Domains and repeats

Domain
11 - 141
Exoribonuclease, phosphorolytic domain 1 (IPR001247)
160 - 224
Exoribonuclease, phosphorolytic domain 2 (IPR015847)

1 50 100 150 200 250 300 350 400 434

Detailed signature matches

IPR027408

PNPase/RNase PH domain superfamily
1. G3DSA:3.30.23...
  
  1 - 231
  
  GENE3D
  G3DSA:3.30.230.70 (G3DSA:3.30.230.70)
IPR020568

Ribosomal protein S5 domain 2-type fold
1. SSF54211 (Ribosomal...)
  
  2 - 182
  
  SUPERFAMILY
  SSF54211 (Ribosomal protein S5 domain 2-like)
IPR036345

Exoribonuclease, PH domain 2 superfamily
1. SSF55666 (Ribonucle...)
  
  154 - 238
  
  SUPERFAMILY
  SSF55666 (Ribonuclease PH domain 2-like)
IPR029001

Inosine triphosphate pyrophosphatase-like
1. SSF52972 (ITPase-like)
  
  238 - 432
  
  SUPERFAMILY
  SSF52972 (ITPase-like)
2. G3DSA:3.90.95...
  
  232 - 433
  
  GENE3D
  G3DSA:3.90.950.10 (G3DSA:3.90.950.10)
IPR002381

Ribonuclease PH, bacterial-type
1. cd11362 (RNase_PH_bact)
  
  11 - 237
  
  CDD
  cd11362 (RNase_PH_bact)
2. MF_00564 (RNase_PH)
  
  2 - 238
  
  HAMAP
  MF_00564 (RNase_PH)
3. TIGR01966
  
  3 - 237
  
  TIGRFAMs
  TIGR01966 (TIGR01966)
IPR002637

Ham1-like protein
1. TIGR00042
  
  243 - 430
  
  TIGRFAMs
  TIGR00042 (TIGR00042)
2. PF01725 (Ham1p_like)
  
  244 - 428
  
  Pfam
  PF01725 (Ham1p_like)
3. cd00515 (HAM1)
  
  244 - 428
  
  CDD
  cd00515 (HAM1)
IPR020922

dITP/XTP pyrophosphatase
1. MF_01405 (Non_canon...)
  
  242 - 432
  
  HAMAP
  MF_01405 (Non_canon_purine_NTPase)
IPR001247

Exoribonuclease, phosphorolytic domain 1
1. PF01138 (RNase_PH)
  
  11 - 141
  
  Pfam
  PF01138 (RNase_PH)
IPR015847

Exoribonuclease, phosphorolytic domain 2
1. PF03725 (RNase_PH_C)
  
  160 - 224
  
  Pfam
  PF03725 (RNase_PH_C)
IPR018336

Ribonuclease PH, conserved site
1. PS01277 (RIBONUCLEA...)
  
  117 - 129
  
  PROSITE patterns
  PS01277 (RIBONUCLEASE_PH)

no IPR

Unintegrated signatures

Coil

409 - 434

COILS
Coil (Coil)

212 - 235

COILS
Coil (Coil)
PTHR11953 (EXOSOME ...)

2 - 239

PANTHER
PTHR11953 (EXOSOME COMPLEX COMPONENT)
PTHR11953:SF0 (EXOS...)

2 - 239

PANTHER
PTHR11953:SF0 (EXOSOME COMPLEX COMPONENT RRP41)

Residue annotation

hexamer interface ...

21V

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

22N

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

23I

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

24Y

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

25A

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

35N

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

37K

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

39I

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

41T

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

43S

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

63E

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

65S

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

67L

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

68P

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

69R

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

70A

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

71T

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

72N

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

74R

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

77R

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

78E

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

86G

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

87R

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

89V

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

90E

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

93R

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

97R

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

100R

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

114T

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

116D

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

118D

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

120I

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

121Q

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

122A

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

197E

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

198F

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

199I

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

200E

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

201V

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

203G

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

205G

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

206E

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

207E

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

208S

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

209T

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

210F

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

212R

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

215L

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

216N

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

219L

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

220D

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)

223E

hexamer interface
21V, 22N, 23I, 24Y, 25A, 35N, 37K, 39I, 41T, 43S, 63E, 65S, 67L, 68P, 69R, 70A, 71T, 72N, 74R, 77R, 78E, 86G, 87R, 89V, 90E, 93R, 97R, 100R, 114T, 116D, 118D, 120I, 121Q, 122A, 197E, 198F, 199I, 200E, 201V, 203G, 205G, 206E, 207E, 208S, 209T, 210F, 212R, 215L, 216N, 219L, 220D, 223E
CDD
cd11362 (RNase_PH_bact)
active site cd11362

66M

active site
66M, 87R, 122A, 123D, 124G, 125G, 126T, 127R, 181D, 187D
CDD
cd11362 (RNase_PH_bact)

87R

active site
66M, 87R, 122A, 123D, 124G, 125G, 126T, 127R, 181D, 187D
CDD
cd11362 (RNase_PH_bact)

122A

active site
66M, 87R, 122A, 123D, 124G, 125G, 126T, 127R, 181D, 187D
CDD
cd11362 (RNase_PH_bact)

123D

active site
66M, 87R, 122A, 123D, 124G, 125G, 126T, 127R, 181D, 187D
CDD
cd11362 (RNase_PH_bact)

124G

active site
66M, 87R, 122A, 123D, 124G, 125G, 126T, 127R, 181D, 187D
CDD
cd11362 (RNase_PH_bact)

125G

active site
66M, 87R, 122A, 123D, 124G, 125G, 126T, 127R, 181D, 187D
CDD
cd11362 (RNase_PH_bact)

126T

active site
66M, 87R, 122A, 123D, 124G, 125G, 126T, 127R, 181D, 187D
CDD
cd11362 (RNase_PH_bact)

127R

active site
66M, 87R, 122A, 123D, 124G, 125G, 126T, 127R, 181D, 187D
CDD
cd11362 (RNase_PH_bact)

181D

active site
66M, 87R, 122A, 123D, 124G, 125G, 126T, 127R, 181D, 187D
CDD
cd11362 (RNase_PH_bact)

187D

active site
66M, 87R, 122A, 123D, 124G, 125G, 126T, 127R, 181D, 187D
CDD
cd11362 (RNase_PH_bact)
active site cd00515

250N

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

252H

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

253K

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

256E

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

312S

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

313G

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

314L

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

327S

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

328A

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

357F

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

391F

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

393Y

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

394D

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

418H

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)

419R

active site
250N, 252H, 253K, 256E, 312S, 313G, 314L, 327S, 328A, 357F, 391F, 393Y, 394D, 418H, 419R
CDD
cd00515 (HAM1)
dimerization inter...

280E

dimerization interface
280E, 284D, 285G, 319L, 320N, 323P, 326Y, 329R
CDD
cd00515 (HAM1)

284D

dimerization interface
280E, 284D, 285G, 319L, 320N, 323P, 326Y, 329R
CDD
cd00515 (HAM1)

285G

dimerization interface
280E, 284D, 285G, 319L, 320N, 323P, 326Y, 329R
CDD
cd00515 (HAM1)

319L

dimerization interface
280E, 284D, 285G, 319L, 320N, 323P, 326Y, 329R
CDD
cd00515 (HAM1)

320N

dimerization interface
280E, 284D, 285G, 319L, 320N, 323P, 326Y, 329R
CDD
cd00515 (HAM1)

323P

dimerization interface
280E, 284D, 285G, 319L, 320N, 323P, 326Y, 329R
CDD
cd00515 (HAM1)

326Y

dimerization interface
280E, 284D, 285G, 319L, 320N, 323P, 326Y, 329R
CDD
cd00515 (HAM1)

329R

dimerization interface
280E, 284D, 285G, 319L, 320N, 323P, 326Y, 329R
CDD
cd00515 (HAM1)

GO term prediction

Biological Process

GO:0008033 tRNA processing
GO:0009143 nucleoside triphosphate catabolic process

Molecular Function

GO:0000049 tRNA binding
GO:0009022 tRNA nucleotidyltransferase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0047429 nucleoside-triphosphate diphosphatase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

25586_FusoPortal_Gene_663

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component