25586_FusoPortal_Gene_775

Protein

25586_FusoPortal_Gene_775

Length

250 amino acids

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)

Homologous superfamilies

Homologous superfamily
3 - 243
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 250 250

Domains and repeats

None predicted.

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  3 - 243
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR002347

Short-chain dehydrogenase/reductase SDR
1. PR00081 (GDHRDH)
  
  70 - 81
  
  PRINTS
  PR00081 (GDHRDH)
  
  2 - 19
  
  PRINTS
  PR00081 (GDHRDH)
  
  164 - 181
  
  PRINTS
  PR00081 (GDHRDH)
  
  117 - 133
  
  PRINTS
  PR00081 (GDHRDH)
2. PF00106 (adh_short)
  
  3 - 187
  
  Pfam
  PF00106 (adh_short)

no IPR

Unintegrated signatures

Coil

40 - 60

COILS
Coil (Coil)
G3DSA:3.40.50...

1 - 250

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PTHR42820 (FAMILY N...)

2 - 222

PANTHER
PTHR42820 (FAMILY NOT NAMED)
PTHR42820:SF1 (SUBF...)

2 - 222

PANTHER
PTHR42820:SF1 (SUBFAMILY NOT NAMED)
cd05233 (SDR_c)

3 - 216

CDD
cd05233 (SDR_c)

Residue annotation

NAD(P) binding sit...

7G

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

9S

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

10S

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

11G

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

12I

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

31G

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

32T

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

33N

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

52V

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

53D

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

54V

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

78S

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

79A

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

80G

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

101I

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

128I

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

129S

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

130S

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

143Y

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

147K

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

173P

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

174G

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

175Y

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

176I

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

178T

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)

179D

NAD(P) binding site
7G, 9S, 10S, 11G, 12I, 31G, 32T, 33N, 52V, 53D, 54V, 78S, 79A, 80G, 101I, 128I, 129S, 130S, 143Y, 147K, 173P, 174G, 175Y, 176I, 178T, 179D
CDD
cd05233 (SDR_c)
active site cd05233

102N

active site
102N, 130S, 143Y, 147K
CDD
cd05233 (SDR_c)

130S

active site
102N, 130S, 143Y, 147K
CDD
cd05233 (SDR_c)

143Y

active site
102N, 130S, 143Y, 147K
CDD
cd05233 (SDR_c)

147K

active site
102N, 130S, 143Y, 147K
CDD
cd05233 (SDR_c)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

25586_FusoPortal_Gene_775

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component