25586_FusoPortal_Gene_827

Protein

25586_FusoPortal_Gene_827

Length

264 amino acids

Protein family membership

Crotonase superfamily (IPR001753)

Homologous superfamilies

Homologous superfamily
3 - 263
ClpP/crotonase-like domain superfamily (IPR029045)
Homologous superfamily
221 - 264
Crontonase, C-terminal (IPR014748)

1 50 100 150 200 264

Domains and repeats

None predicted.

Detailed signature matches

IPR029045

ClpP/crotonase-like domain superfamily
1. SSF52096 (ClpP/crot...)
  
  3 - 263
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
IPR014748

Crontonase, C-terminal
1. G3DSA:1.10.12.10
  
  221 - 264
  
  GENE3D
  G3DSA:1.10.12.10 (G3DSA:1.10.12.10)
IPR001753

Crotonase superfamily
1. PF00378 (ECH_1)
  
  11 - 263
  
  Pfam
  PF00378 (ECH_1)

no IPR

Unintegrated signatures

G3DSA:3.90.22...

2 - 220

GENE3D
G3DSA:3.90.226.10 (G3DSA:3.90.226.10)
PTHR11941 (ENOYL-CO...)

6 - 263

PANTHER
PTHR11941 (ENOYL-COA HYDRATASE-RELATED)
PTHR11941:SF76 (1,2...)

6 - 263

PANTHER
PTHR11941:SF76 (1,2-EPOXYPHENYLACETYL-COA ISOMERASE)
cd06558 (crotonase-...)

6 - 202

CDD
cd06558 (crotonase-like)

Residue annotation

substrate binding ...

25L

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

27A

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

59K

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

63A

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

64G

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

65G

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

66D

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

67I

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

110A

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

112A

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

113G

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

114A

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

136A

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

137F

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)

140L

substrate binding site
25L, 27A, 59K, 63A, 64G, 65G, 66D, 67I, 110A, 112A, 113G, 114A, 136A, 137F, 140L
CDD
cd06558 (crotonase-like)
oxyanion hole (OAH...

65G

oxyanion hole (OAH) forming residues
65G, 114A
CDD
cd06558 (crotonase-like)

114A

oxyanion hole (OAH) forming residues
65G, 114A
CDD
cd06558 (crotonase-like)
trimer interface c...

94D

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

102I

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

123D

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

124F

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

125I

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

126I

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

138V

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

139N

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

140L

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

141G

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

147G

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

149T

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

150Y

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

151L

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

153S

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

154K

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

159P

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

160R

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

162M

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

163E

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

165A

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

166A

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

169R

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

180G

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

183Y

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

198F

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

201K

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

202I

trimer interface
94D, 102I, 123D, 124F, 125I, 126I, 138V, 139N, 140L, 141G, 147G, 149T, 150Y, 151L, 153S, 154K, 159P, 160R, 162M, 163E, 165A, 166A, 169R, 180G, 183Y, 198F, 201K, 202I
CDD
cd06558 (crotonase-like)

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

25586_FusoPortal_Gene_827

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component