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Entry type
Status
Per-residue features
Colour by
25586_FusoPortal_Gene_982
Length
237 amino acids
Protein family membership
- Orotidine 5'-phosphate decarboxylase (IPR014732)
Homologous superfamilies
-
Homologous superfamily1 - 229
- Aldolase-type TIM barrel (IPR013785)
-
Homologous superfamily2 - 228
- Ribulose-phosphate binding barrel (IPR011060)
1
50
100
150
200
237
Domains and repeats
-
Domain4 - 223
- Orotidine 5'-phosphate decarboxylase domain (IPR001754)
1
50
100
150
200
237
Detailed signature matches
-
-
1 - 229
-
-
-
5 - 225
-
MF_01200_B (OMPdeca...)2 - 230
-
PTHR32119:SF2 (OROT...)2 - 229
-
Residue annotation
-
active site cd047258Aactive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like)10Dactive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like)32Kactive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like)34Gactive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like)59Dactive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like)61Kactive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like)117Lactive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like)118Tactive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like)177Pactive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like)209Gactive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like)210Ractive site
8A, 10D, 32K, 34G, 59D, 61K, 117L, 118T, 177P, 209G, 210R
CDD
cd04725 (OMP_decarboxylase_like) -
dimer interface cd...34Gdimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)36Edimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)37Ldimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)60Ldimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)61Kdimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)63Hdimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)64Ddimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)67Ndimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)68Tdimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)71Sdimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)72Adimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)87Hdimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)88Adimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)89Adimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)100Rdimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)117Ldimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)138Sdimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)210Rdimer interface
34G, 36E, 37L, 60L, 61K, 63H, 64D, 67N, 68T, 71S, 72A, 87H, 88A, 89A, 100R, 117L, 138S, 210R
CDD
cd04725 (OMP_decarboxylase_like)
GO term prediction
Biological Process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0008152 metabolic process
GO:0044205 'de novo' UMP biosynthetic process
Molecular Function
GO:0003824 catalytic activity
GO:0004590 orotidine-5'-phosphate decarboxylase activity
Cellular Component
None predicted.