27725_FusoPortal_Gene_140

Protein

27725_FusoPortal_Gene_140

Length

191 amino acids

Protein family membership

Clp protease proteolytic subunit /Translocation-enhancing protein TepA (IPR023562)
- ATP-dependent Clp protease proteolytic subunit (IPR001907)

Homologous superfamilies

Homologous superfamily
10 - 189
ClpP/crotonase-like domain superfamily (IPR029045)

1 20 40 60 80 100 120 140 160 180 191

Domains and repeats

None predicted.

Detailed signature matches

IPR029045

ClpP/crotonase-like domain superfamily
1. SSF52096 (ClpP/crot...)
  
  10 - 189
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
IPR023562

Clp protease proteolytic subunit /Translocation-enhancing protein TepA
1. PTHR10381 (ATP-DEPE...)
  
  3 - 190
  
  PANTHER
  PTHR10381 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT)
2. PF00574 (CLP_protease)
  
  12 - 190
  
  Pfam
  PF00574 (CLP_protease)
IPR001907

ATP-dependent Clp protease proteolytic subunit
1. MF_00444 (ClpP)
  
  2 - 191
  
  HAMAP
  MF_00444 (ClpP)
2. TIGR00493
  
  3 - 191
  
  TIGRFAMs
  TIGR00493 (TIGR00493)
3. PR00127 (CLPPROTEASEP)
  
  167 - 186
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  58 - 78
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  110 - 129
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  18 - 33
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  89 - 106
  
  PRINTS
  PR00127 (CLPPROTEASEP)
4. cd07017 (S14_ClpP_2)
  
  18 - 188
  
  CDD
  cd07017 (S14_ClpP_2)
IPR018215

ClpP, Ser active site
1. PS00381 (CLP_PROTEA...)
  
  89 - 100
  
  PROSITE patterns
  PS00381 (CLP_PROTEASE_SER)
IPR033135

ClpP, histidine active site
1. PS00382 (CLP_PROTEA...)
  
  111 - 124
  
  PROSITE patterns
  PS00382 (CLP_PROTEASE_HIS)

no IPR

Unintegrated signatures

G3DSA:3.90.22...

1 - 191

GENE3D
G3DSA:3.90.226.10 (G3DSA:3.90.226.10)
PTHR10381:SF11 (ATP...)

3 - 190

PANTHER
PTHR10381:SF11 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL)

Residue annotation

oligomer interface...

30F

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

32G

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

41N

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

42A

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

45A

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

46Q

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

49F

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

64N

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

71T

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

75A

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

78D

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

81N

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

82Y

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

86D

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

94Q

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

116H

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

118R

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

124P

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

125L

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

126G

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

127G

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

141E

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

144R

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

146K

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

148M

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

171D

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)

173Y

oligomer interface
30F, 32G, 41N, 42A, 45A, 46Q, 49F, 64N, 71T, 75A, 78D, 81N, 82Y, 86D, 94Q, 116H, 118R, 124P, 125L, 126G, 127G, 141E, 144R, 146K, 148M, 171D, 173Y
CDD
cd07017 (S14_ClpP_2)
active site residu...

97S

active site residues
97S, 122H, 171D
CDD
cd07017 (S14_ClpP_2)

122H

active site residues
97S, 122H, 171D
CDD
cd07017 (S14_ClpP_2)

171D

active site residues
97S, 122H, 171D
CDD
cd07017 (S14_ClpP_2)

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

27725_FusoPortal_Gene_140

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component