27725_FusoPortal_Gene_1533

Protein

27725_FusoPortal_Gene_1533

Length

823 amino acids

Protein family membership

P-type ATPase (IPR001757)
- P-type ATPase, subfamily IB (IPR027256)

Homologous superfamilies

Homologous superfamily
1 - 67
Heavy metal-associated domain superfamily (IPR036163)
71 - 139
Heavy metal-associated domain superfamily (IPR036163)
305 - 401
P-type ATPase, A domain superfamily (IPR008250)
526 - 634
P-type ATPase, cytoplasmic domain N (IPR023299)
635 - 772
HAD superfamily (IPR023214)
Homologous superfamily
269 - 305
P-type ATPase, transmembrane domain superfamily (IPR023298)
402 - 502
P-type ATPase, transmembrane domain superfamily (IPR023298)
509 - 528
HAD-like superfamily (IPR036412)
567 - 815
HAD-like superfamily (IPR036412)

1 100 200 300 400 500 600 700 823

Domains and repeats

Domain
2 - 68
Heavy metal-associated domain, HMA (IPR006121)
Heavy metal-associated domain, copper ion-binding (IPR006122)
74 - 140
Heavy metal-associated domain, HMA (IPR006121)
Heavy metal-associated domain, copper ion-binding (IPR006122)

1 100 200 300 400 500 600 700 823

Detailed signature matches

IPR036163

Heavy metal-associated domain superfamily
1. SSF55008 (HMA, heav...)
  
  71 - 139
  
  SUPERFAMILY
  SSF55008 (HMA, heavy metal-associated domain)
  
  1 - 67
  
  SUPERFAMILY
  SSF55008 (HMA, heavy metal-associated domain)
IPR023298

P-type ATPase, transmembrane domain superfamily
1. SSF81665 (Calcium A...)
  
  269 - 305
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
  
  402 - 502
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
IPR008250

P-type ATPase, A domain superfamily
1. SSF81653 (Calcium A...)
  
  305 - 401
  
  SUPERFAMILY
  SSF81653 (Calcium ATPase, transduction domain A)
IPR036412

HAD-like superfamily
1. SSF56784 (HAD-like)
  
  567 - 815
  
  SUPERFAMILY
  SSF56784 (HAD-like)
  
  509 - 528
  
  SUPERFAMILY
  SSF56784 (HAD-like)
IPR023299

P-type ATPase, cytoplasmic domain N
1. G3DSA:3.40.11...
  
  526 - 634
  
  GENE3D
  G3DSA:3.40.1110.10 (G3DSA:3.40.1110.10)
IPR023214

HAD superfamily
1. G3DSA:3.40.50...
  
  635 - 772
  
  GENE3D
  G3DSA:3.40.50.1000 (G3DSA:3.40.50.1000)
IPR001757

P-type ATPase
1. TIGR01494
  
  273 - 785
  
  TIGRFAMs
  TIGR01494 (TIGR01494)
IPR027256

P-type ATPase, subfamily IB
1. TIGR01525
  
  233 - 817
  
  TIGRFAMs
  TIGR01525 (TIGR01525)
IPR006121

Heavy metal-associated domain, HMA
1. PS50846 (HMA_2)
  
  74 - 140
  
  PROSITE profiles
  PS50846 (HMA_2)
  
  2 - 68
  
  PROSITE profiles
  PS50846 (HMA_2)
2. PF00403 (HMA)
  
  7 - 65
  
  Pfam
  PF00403 (HMA)
  
  77 - 137
  
  Pfam
  PF00403 (HMA)
3. cd00371 (HMA)
  
  76 - 136
  
  CDD
  cd00371 (HMA)
  
  5 - 67
  
  CDD
  cd00371 (HMA)
IPR006122

Heavy metal-associated domain, copper ion-binding
1. TIGR00003
  
  75 - 136
  
  TIGRFAMs
  TIGR00003 (TIGR00003)
  
  2 - 67
  
  TIGRFAMs
  TIGR00003 (TIGR00003)
IPR018303

P-type ATPase, phosphorylation site
1. PS00154 (ATPASE_E1_E2)
  
  512 - 518
  
  PROSITE patterns
  PS00154 (ATPASE_E1_E2)

no IPR

Unintegrated signatures

G3DSA:1.20.11...

267 - 525

GENE3D
G3DSA:1.20.1110.10 (G3DSA:1.20.1110.10)
G3DSA:3.30.70...

1 - 71

GENE3D
G3DSA:3.30.70.100 (G3DSA:3.30.70.100)

72 - 150

GENE3D
G3DSA:3.30.70.100 (G3DSA:3.30.70.100)
PF00122 (E1-E2_ATPase)

302 - 488

Pfam
PF00122 (E1-E2_ATPase)
PF00702 (Hydrolase)

506 - 722

Pfam
PF00702 (Hydrolase)
PR00119 (CATATPASE)

351 - 365

PRINTS
PR00119 (CATATPASE)

510 - 524

PRINTS
PR00119 (CATATPASE)

633 - 644

PRINTS
PR00119 (CATATPASE)

708 - 727

PRINTS
PR00119 (CATATPASE)

655 - 665

PRINTS
PR00119 (CATATPASE)

731 - 743

PRINTS
PR00119 (CATATPASE)
PR00942 (CUATPASEI)

28 - 51

PRINTS
PR00942 (CUATPASEI)

216 - 241

PRINTS
PR00942 (CUATPASEI)

2 - 27

PRINTS
PR00942 (CUATPASEI)

97 - 118

PRINTS
PR00942 (CUATPASEI)
PTHR43520 (FAMILY N...)

4 - 823

PANTHER
PTHR43520 (FAMILY NOT NAMED)
SFLDF00027 (p-type_...)

491 - 759

SFLD
SFLDF00027 (p-type_atpase)
SFLDG00002 (C1.7:_P...)

491 - 759

SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
TIGR01511

214 - 818

TIGRFAMs
TIGR01511 (TIGR01511)
TIGR01512

269 - 817

TIGRFAMs
TIGR01512 (TIGR01512)
cd02094 (P-type_ATP...)

164 - 819

CDD
cd02094 (P-type_ATPase_Cu-like)

Residue annotation

metal-binding site...

10I

metal-binding site
10I, 11S, 12C, 15C
CDD
cd00371 (HMA)

11S

metal-binding site
10I, 11S, 12C, 15C
CDD
cd00371 (HMA)

12C

metal-binding site
10I, 11S, 12C, 15C
CDD
cd00371 (HMA)

15C

metal-binding site
10I, 11S, 12C, 15C
CDD
cd00371 (HMA)
metal-binding site...

82I

metal-binding site
82I, 83S, 84C, 87C
CDD
cd00371 (HMA)

83S

metal-binding site
82I, 83S, 84C, 87C
CDD
cd00371 (HMA)

84C

metal-binding site
82I, 83S, 84C, 87C
CDD
cd00371 (HMA)

87C

metal-binding site
82I, 83S, 84C, 87C
CDD
cd00371 (HMA)
HM-ATPase signatur...

468C

HM-ATPase signature motif
468C, 469P, 470C
CDD
cd02094 (P-type_ATPase_Cu-like)

469P

HM-ATPase signature motif
468C, 469P, 470C
CDD
cd02094 (P-type_ATPase_Cu-like)

470C

HM-ATPase signature motif
468C, 469P, 470C
CDD
cd02094 (P-type_ATPase_Cu-like)
putative Cu bindin...

468C

putative Cu binding site
468C, 470C, 774Y
CDD
cd02094 (P-type_ATPase_Cu-like)

470C

putative Cu binding site
468C, 470C, 774Y
CDD
cd02094 (P-type_ATPase_Cu-like)

774Y

putative Cu binding site
468C, 470C, 774Y
CDD
cd02094 (P-type_ATPase_Cu-like)
phosphorylation si...

512D

phosphorylation site
512D
CDD
cd02094 (P-type_ATPase_Cu-like)
P-type ATPase sign...

512D

P-type ATPase signature motif
512D, 513K, 514T, 515G, 516T, 517L, 518T
CDD
cd02094 (P-type_ATPase_Cu-like)

513K

P-type ATPase signature motif
512D, 513K, 514T, 515G, 516T, 517L, 518T
CDD
cd02094 (P-type_ATPase_Cu-like)

514T

P-type ATPase signature motif
512D, 513K, 514T, 515G, 516T, 517L, 518T
CDD
cd02094 (P-type_ATPase_Cu-like)

515G

P-type ATPase signature motif
512D, 513K, 514T, 515G, 516T, 517L, 518T
CDD
cd02094 (P-type_ATPase_Cu-like)

516T

P-type ATPase signature motif
512D, 513K, 514T, 515G, 516T, 517L, 518T
CDD
cd02094 (P-type_ATPase_Cu-like)

517L

P-type ATPase signature motif
512D, 513K, 514T, 515G, 516T, 517L, 518T
CDD
cd02094 (P-type_ATPase_Cu-like)

518T

P-type ATPase signature motif
512D, 513K, 514T, 515G, 516T, 517L, 518T
CDD
cd02094 (P-type_ATPase_Cu-like)
putative ATP bindi...

512D

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

513K

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

514T

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

577I

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

593I

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

594G

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

595N

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

623M

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

663T

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

664G

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

665D

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

685E

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

688P

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

691K

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

710D

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)

713N

putative ATP binding site
512D, 513K, 514T, 577I, 593I, 594G, 595N, 623M, 663T, 664G, 665D, 685E, 688P, 691K, 710D, 713N
CDD
cd02094 (P-type_ATPase_Cu-like)
SFLDG00002

512D

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

513K

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

514T

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

515G

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

516T

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

663T

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

691K

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

710D

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

714D

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
SFLDF00027

512D

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDF00027 (p-type_atpase)

513K

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDF00027 (p-type_atpase)

514T

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDF00027 (p-type_atpase)

515G

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDF00027 (p-type_atpase)

516T

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDF00027 (p-type_atpase)

663T

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDF00027 (p-type_atpase)

691K

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDF00027 (p-type_atpase)

710D

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDF00027 (p-type_atpase)

714D

SFLD_Res01
512D, 513K, 514T, 515G, 516T, 663T, 691K, 710D, 714D
SFLD
SFLDF00027 (p-type_atpase)
putative Cu bindin...

775N

putative Cu binding site
775N, 803M, 807S
CDD
cd02094 (P-type_ATPase_Cu-like)

803M

putative Cu binding site
775N, 803M, 807S
CDD
cd02094 (P-type_ATPase_Cu-like)

807S

putative Cu binding site
775N, 803M, 807S
CDD
cd02094 (P-type_ATPase_Cu-like)

GO term prediction

Biological Process

GO:0006812 cation transport
GO:0030001 metal ion transport

Molecular Function

GO:0000166 nucleotide binding
GO:0005507 copper ion binding
GO:0019829 cation-transporting ATPase activity
GO:0046872 metal ion binding

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features

27725_FusoPortal_Gene_1533

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component