27725_FusoPortal_Gene_176

Protein

27725_FusoPortal_Gene_176

Length

287 amino acids

Protein family membership

Glucose-1-phosphate thymidylyltransferase, short form (IPR005907)

Homologous superfamilies

Homologous superfamily
1 - 287
Nucleotide-diphospho-sugar transferases (IPR029044)

1 50 100 150 200 250 287

Domains and repeats

Domain
2 - 237
Nucleotidyl transferase domain (IPR005835)

1 50 100 150 200 250 287

Detailed signature matches

IPR029044

Nucleotide-diphospho-sugar transferases
1. G3DSA:3.90.55...
  
  1 - 287
  
  GENE3D
  G3DSA:3.90.550.10 (G3DSA:3.90.550.10)
2. SSF53448 (Nucleotid...)
  
  1 - 286
  
  SUPERFAMILY
  SSF53448 (Nucleotide-diphospho-sugar transferases)
IPR005907

Glucose-1-phosphate thymidylyltransferase, short form
1. cd02538 (G1P_TT_short)
  
  1 - 240
  
  CDD
  cd02538 (G1P_TT_short)
2. PTHR43532 (FAMILY N...)
  
  2 - 286
  
  PANTHER
  PTHR43532 (FAMILY NOT NAMED)
3. TIGR01207
  
  2 - 287
  
  TIGRFAMs
  TIGR01207 (TIGR01207)
IPR005835

Nucleotidyl transferase domain
1. PF00483 (NTP_transf...)
  
  2 - 237
  
  Pfam
  PF00483 (NTP_transferase)

no IPR

Unintegrated signatures

PTHR43532:SF1 (GLUC...)

2 - 286

PANTHER
PTHR43532:SF1 (GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE 1)

Residue annotation

substrate binding ...

6L

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

8G

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

9G

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

80Q

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

83P

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

84N

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

85G

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

86L

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

108D

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

144G

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

159E

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

160K

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

170V

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)

198T

substrate binding site
6L, 8G, 9G, 80Q, 83P, 84N, 85G, 86L, 108D, 144G, 159E, 160K, 170V, 198T
CDD
cd02538 (G1P_TT_short)
tetramer interface...

12T

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

15Y

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

16P

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

17I

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

20S

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

21I

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

25I

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

26T

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

27P

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

29Y

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

30D

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

31K

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

32P

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

35Y

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

60M

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

112Y

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

113G

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

135Y

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

136Y

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

137V

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

138Q

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

142D

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

143F

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

221W

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

222L

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

223D

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

227H

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

228E

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

231L

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

234A

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

235N

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

236Y

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

239T

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

240I

tetramer interface
12T, 15Y, 16P, 17I, 20S, 21I, 25I, 26T, 27P, 29Y, 30D, 31K, 32P, 35Y, 60M, 112Y, 113G, 135Y, 136Y, 137V, 138Q, 142D, 143F, 221W, 222L, 223D, 227H, 228E, 231L, 234A, 235N, 236Y, 239T, 240I
CDD
cd02538 (G1P_TT_short)

GO term prediction

Biological Process

GO:0009058 biosynthetic process
GO:0045226 extracellular polysaccharide biosynthetic process

Molecular Function

GO:0008879 glucose-1-phosphate thymidylyltransferase activity
GO:0016779 nucleotidyltransferase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

27725_FusoPortal_Gene_176

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component