27725_FusoPortal_Gene_1825

Protein

27725_FusoPortal_Gene_1825

Length

395 amino acids

Protein family membership

Peptidase M20 (IPR002933)
- N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase (IPR010182)

Homologous superfamilies

Homologous superfamily
188 - 289
Bacterial exopeptidase dimerisation domain (IPR036264)

1 50 100 150 200 250 300 350 395

Domains and repeats

Domain
186 - 287
Peptidase M20, dimerisation domain (IPR011650)

1 50 100 150 200 250 300 350 395

Detailed signature matches

IPR036264

Bacterial exopeptidase dimerisation domain
1. SSF55031 (Bacterial...)
  
  188 - 289
  
  SUPERFAMILY
  SSF55031 (Bacterial exopeptidase dimerisation domain)
IPR002933

Peptidase M20
1. PF01546 (Peptidase_M20)
  
  74 - 390
  
  Pfam
  PF01546 (Peptidase_M20)
IPR010182

N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase
1. TIGR01910
  
  9 - 384
  
  TIGRFAMs
  TIGR01910 (TIGR01910)
IPR011650

Peptidase M20, dimerisation domain
1. PF07687 (M20_dimer)
  
  186 - 287
  
  Pfam
  PF07687 (M20_dimer)
IPR001261

ArgE/DapE/ACY1/CPG2/YscS, conserved site
1. PS00758 (ARGE_DAPE_...)
  
  73 - 82
  
  PROSITE patterns
  PS00758 (ARGE_DAPE_CPG2_1)

no IPR

Unintegrated signatures

G3DSA:3.40.63...

2 - 288

GENE3D
G3DSA:3.40.630.10 (G3DSA:3.40.630.10)
PTHR43808 (FAMILY N...)

2 - 391

PANTHER
PTHR43808 (FAMILY NOT NAMED)
SSF53187 (Zn-depend...)

3 - 188

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

310 - 392

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)
cd08659 (M20_ArgE_D...)

9 - 389

CDD
cd08659 (M20_ArgE_DapE_like)

Residue annotation

metal binding site...

78H

metal binding site
78H, 109D, 143E, 144E, 170E, 367H
CDD
cd08659 (M20_ArgE_DapE_like)

109D

metal binding site
78H, 109D, 143E, 144E, 170E, 367H
CDD
cd08659 (M20_ArgE_DapE_like)

143E

metal binding site
78H, 109D, 143E, 144E, 170E, 367H
CDD
cd08659 (M20_ArgE_DapE_like)

144E

metal binding site
78H, 109D, 143E, 144E, 170E, 367H
CDD
cd08659 (M20_ArgE_DapE_like)

170E

metal binding site
78H, 109D, 143E, 144E, 170E, 367H
CDD
cd08659 (M20_ArgE_DapE_like)

367H

metal binding site
78H, 109D, 143E, 144E, 170E, 367H
CDD
cd08659 (M20_ArgE_DapE_like)
dimer interface cd...

192G

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

203H

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

204A

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

205A

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

206T

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

212N

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

214V

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

215E

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

218G

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

219K

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

221I

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

222V

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

239S

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

241C

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

242V

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

243I

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

244E

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

245I

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

246E

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

247G

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

248G

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

254V

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

255P

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

263F

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

265H

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

340S

dimer interface
192G, 203H, 204A, 205A, 206T, 212N, 214V, 215E, 218G, 219K, 221I, 222V, 239S, 241C, 242V, 243I, 244E, 245I, 246E, 247G, 248G, 254V, 255P, 263F, 265H, 340S
CDD
cd08659 (M20_ArgE_DapE_like)

GO term prediction

Biological Process

GO:0006508 proteolysis
GO:0008152 metabolic process

Molecular Function

GO:0008237 metallopeptidase activity
GO:0016787 hydrolase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

27725_FusoPortal_Gene_1825

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component