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Protein

27725_FusoPortal_Gene_2443

Length

274 amino acids

Protein family membership

Glucosamine-6-phosphate isomerase (IPR004547)

Homologous superfamilies

Homologous superfamily
6 - 261
NagB/RpiA transferase-like (IPR037171)

1 50 100 150 200 274

Domains and repeats

Domain
11 - 216
Glucosamine/galactosamine-6-phosphate isomerase (IPR006148)

1 50 100 150 200 274

Detailed signature matches

IPR037171

NagB/RpiA transferase-like

SSF100950 (NagB/Rpi...)

6 - 261

SUPERFAMILY
SSF100950 (NagB/RpiA/CoA transferase-like)

IPR004547

Glucosamine-6-phosphate isomerase

PTHR11280 (GLUCOSAM...)

1 - 263

PANTHER
PTHR11280 (GLUCOSAMINE-6-PHOSPHATE ISOMERASE)
TIGR00502

1 - 257

TIGRFAMs
TIGR00502 (TIGR00502)
cd01399 (GlcN6P_dea...)

8 - 245

CDD
cd01399 (GlcN6P_deaminase)
MF_01241 (GlcN6P_de...)

1 - 245

HAMAP
MF_01241 (GlcN6P_deamin)

IPR006148

Glucosamine/galactosamine-6-phosphate isomerase

PF01182 (Glucosamin...)

11 - 216

Pfam
PF01182 (Glucosamine_iso)

IPR018321

Glucosamine-6-phosphate isomerase, conserved site

PS01161 (GLC_GALNAC...)

123 - 141

PROSITE patterns
PS01161 (GLC_GALNAC_ISOMERASE)

no IPR

Unintegrated signatures

Coil

95 - 129

COILS
Coil (Coil)
G3DSA:3.40.50...

1 - 264

GENE3D
G3DSA:3.40.50.1360 (G3DSA:3.40.50.1360)
PTHR11280:SF17 (GLU...)

1 - 263

PANTHER
PTHR11280:SF17 (GLUCOSAMINE-6-PHOSPHATE ISOMERASE)

Residue annotation

active site cd01399

39T

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

40G

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

41G

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

42T

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

69M

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

70D

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

135G

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

136I

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

141H

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

143A

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

170R

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)

206K

active site
39T, 40G, 41G, 42T, 69M, 70D, 135G, 136I, 141H, 143A, 170R, 206K
CDD
cd01399 (GlcN6P_deaminase)
trimer interface c...

148G

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

150S

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

151L

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

159E

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

214V

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

215E

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

216E

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

217G

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

218V

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

219N

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

220H

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

228Q

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

229L

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)

230H

trimer interface
148G, 150S, 151L, 159E, 214V, 215E, 216E, 217G, 218V, 219N, 220H, 228Q, 229L, 230H
CDD
cd01399 (GlcN6P_deaminase)
allosteric site cd...

149S

allosteric site
149S, 150S, 156R, 157D, 158K, 159E
CDD
cd01399 (GlcN6P_deaminase)

150S

allosteric site
149S, 150S, 156R, 157D, 158K, 159E
CDD
cd01399 (GlcN6P_deaminase)

156R

allosteric site
149S, 150S, 156R, 157D, 158K, 159E
CDD
cd01399 (GlcN6P_deaminase)

157D

allosteric site
149S, 150S, 156R, 157D, 158K, 159E
CDD
cd01399 (GlcN6P_deaminase)

158K

allosteric site
149S, 150S, 156R, 157D, 158K, 159E
CDD
cd01399 (GlcN6P_deaminase)

159E

allosteric site
149S, 150S, 156R, 157D, 158K, 159E
CDD
cd01399 (GlcN6P_deaminase)
active site lid cd...

161T

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

164T

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

165I

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

166V

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

167A

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

168N

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

169A

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

170R

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

171F

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

172F

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

173G

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

174G

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

178A

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

179V

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)

180P

active site lid
161T, 164T, 165I, 166V, 167A, 168N, 169A, 170R, 171F, 172F, 173G, 174G, 178A, 179V, 180P
CDD
cd01399 (GlcN6P_deaminase)
hexamer (dimer of ...

166V

hexamer (dimer of trimers) interface
166V, 204L, 208R, 239E, 242C, 243A, 244E, 245L
CDD
cd01399 (GlcN6P_deaminase)

204L

hexamer (dimer of trimers) interface
166V, 204L, 208R, 239E, 242C, 243A, 244E, 245L
CDD
cd01399 (GlcN6P_deaminase)

208R

hexamer (dimer of trimers) interface
166V, 204L, 208R, 239E, 242C, 243A, 244E, 245L
CDD
cd01399 (GlcN6P_deaminase)

239E

hexamer (dimer of trimers) interface
166V, 204L, 208R, 239E, 242C, 243A, 244E, 245L
CDD
cd01399 (GlcN6P_deaminase)

242C

hexamer (dimer of trimers) interface
166V, 204L, 208R, 239E, 242C, 243A, 244E, 245L
CDD
cd01399 (GlcN6P_deaminase)

243A

hexamer (dimer of trimers) interface
166V, 204L, 208R, 239E, 242C, 243A, 244E, 245L
CDD
cd01399 (GlcN6P_deaminase)

244E

hexamer (dimer of trimers) interface
166V, 204L, 208R, 239E, 242C, 243A, 244E, 245L
CDD
cd01399 (GlcN6P_deaminase)

245L

hexamer (dimer of trimers) interface
166V, 204L, 208R, 239E, 242C, 243A, 244E, 245L
CDD
cd01399 (GlcN6P_deaminase)

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0006044 N-acetylglucosamine metabolic process

Molecular Function

GO:0004342 glucosamine-6-phosphate deaminase activity

Cellular Component

None predicted.