27725_FusoPortal_Gene_2672

Protein

27725_FusoPortal_Gene_2672

Length

308 amino acids

Protein family membership

Homoserine kinase, type II (IPR005280)

Homologous superfamilies

Homologous superfamily
7 - 280
Protein kinase-like domain superfamily (IPR011009)

1 50 100 150 200 250 308

Domains and repeats

Domain
27 - 229
Aminoglycoside phosphotransferase (IPR002575)

1 50 100 150 200 250 308

Detailed signature matches

IPR011009

Protein kinase-like domain superfamily
1. SSF56112 (Protein k...)
  
  7 - 280
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR005280

Homoserine kinase, type II
1. cd05153 (Homoserine...)
  
  11 - 306
  
  CDD
  cd05153 (HomoserineK_II)
IPR002575

Aminoglycoside phosphotransferase
1. PF01636 (APH)
  
  27 - 229
  
  Pfam
  PF01636 (APH)

no IPR

Unintegrated signatures

G3DSA:3.30.20...

2 - 95

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
G3DSA:3.90.12...

96 - 285

GENE3D
G3DSA:3.90.1200.10 (G3DSA:3.90.1200.10)
PTHR21064 (UNCHARAC...)

12 - 303

PANTHER
PTHR21064 (UNCHARACTERIZED)

Residue annotation

ATP binding site c...

29I

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

33I

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

37N

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

48V

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

50R

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

78S

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

100F

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

101Y

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

102F

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

103I

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

188D

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

192D

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

193N

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

195L

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

205I

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)

206D

ATP binding site
29I, 33I, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 192D, 193N, 195L, 205I, 206D
CDD
cd05153 (HomoserineK_II)
putative active si...

29I

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

32G

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

33I

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

34L

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

37N

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

48V

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

50R

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

78S

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

100F

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

101Y

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

102F

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

103I

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

188D

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

190F

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

192D

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

193N

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

195L

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

205I

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

206D

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

209D

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

224N

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

225Y

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

228R

putative active site
29I, 32G, 33I, 34L, 37N, 48V, 50R, 78S, 100F, 101Y, 102F, 103I, 188D, 190F, 192D, 193N, 195L, 205I, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)
putative substrate...

32G

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

33I

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

34L

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

188D

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

190F

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

193N

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

206D

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

209D

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

224N

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

225Y

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

228R

putative substrate binding site
32G, 33I, 34L, 188D, 190F, 193N, 206D, 209D, 224N, 225Y, 228R
CDD
cd05153 (HomoserineK_II)

GO term prediction

Biological Process

GO:0009088 threonine biosynthetic process

Molecular Function

GO:0004413 homoserine kinase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

27725_FusoPortal_Gene_2672

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component